Revenue
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $14.1M | $6.2M | $18.1M | $39.0M | $11.0M | $6.9M | $6.0M | $5.9M | $10.7M | $1.5M | $23.3M | $15.0M | $15.5M | $14.1M | $16.8M | — |
| Research & development | $25.2M | $54.0M | $73.7M | $84.4M | $65.5M | $49.3M | $57.6M | $57.9M | $62.7M | $61.3M | $51.5M | $38.7M | $21.5M | $18.0M | $20.1M | — |
| Operating expenses | $52.2M | $82.5M | $96.2M | $104.5M | $84.5M | $64.7M | $149.9M | $95.7M | $121.6M | $493.1M | $127.2M | $48.4M | $27.6M | $27.1M | $27.5M | — |
| Operating income | −$38.2M | −$76.3M | −$78.1M | −$65.5M | −$73.5M | −$57.8M | −$143.9M | −$89.8M | −$110.9M | −$491.6M | −$103.9M | −$33.4M | −$12.2M | −$12.9M | −$10.7M | — |
| Operating margin | −270.96% | −1,236.74% | −430.53% | −167.75% | −669.11% | −836.07% | −2,393.96% | −1,510.18% | −1,036.73% | −32,973.78% | −446.46% | −223.59% | −78.58% | −91.78% | −63.61% | — |
| EBITDA | −$37.8M | −$74.9M | −$76.7M | −$64.0M | −$71.8M | −$55.8M | −$141.9M | −$87.6M | −$108.9M | −$490.5M | −$103.3M | −$32.9M | −$11.5M | −$12.1M | −$9.7M | — |
| EBITDA margin | −268.39% | −1,214.37% | −422.79% | −164.10% | −653.16% | −807.46% | −2,360.22% | −1,473.49% | −1,017.79% | −32,900.54% | −443.93% | −220.06% | −74.61% | −85.64% | −57.74% | — |
| Net income | −$33.5M | −$69.9M | −$72.8M | −$69.5M | −$76.2M | −$63.7M | −$153.7M | −$57.1M | −$84.4M | −$384.2M | −$62.7M | −$38.8M | −$14.1M | $29.6M | −$10.1M | — |
| Net profit margin | −237.88% | −1,133.04% | −401.57% | −178.01% | −693.91% | −921.97% | −2,557.36% | −959.80% | −788.91% | −25,765.53% | −269.45% | −259.73% | −90.93% | 209.93% | −59.98% | — |
| Basic EPSper basic share | -$0.17 | -$0.38 | -$0.44 | -$0.46 | -$0.83 | -$1.00 | -$2.89 | -$1.21 | -$1.56 | -$7.24 | -$1.38 | -$1.80 | -$0.92 | $2.16 | -$0.89 | — |
| Diluted EPSper diluted share | -$0.17 | -$0.38 | -$0.44 | -$0.46 | -$0.83 | -$1.00 | -$2.89 | -$1.21 | -$1.56 | -$7.24 | -$1.38 | -$1.80 | -$0.92 | $2.07 | -$0.89 | — |
Reported shareholders
| Holder | % owned |
|---|---|
Gline Matthew | ≈19.66%38.85M shares |
Two Seas Capital LP | 9.66%19.1M shares |
MORGAN STANLEY | 8.96%17.7M shares |
Whitefort Capital Management, LP | 7.99%15.79M shares |
BlackRock, Inc. | 6.97%13.77M shares |
STATE STREET CORP | 3.98%7.87M shares |
Rubric Capital Management LP | 3.81%7.53M shares |
VANGUARD CAPITAL MANAGEMENT LLC | 3.55%7.01M shares |
BARCLAYS PLC | 2.13%4.21M shares |
GEODE CAPITAL MANAGEMENT, LLC | 2.08%4.12M shares |
GOLDMAN SACHS GROUP INC | 1.77%3.51M shares |
BANK OF AMERICA CORP /DE/ | 1.34%2.65M shares |
BlackBarn Capital Partners LP | 1.26%2.5M shares |
Legal & General Group Plc | 1.25%2.47M shares |
Woodline Partners LP | 1.15%2.28M shares |
Jefferies Financial Group Inc. | 0.87%1.71M shares |
McElhaugh Michael J. | ≈0.84%1.66M shares |
NOMURA HOLDINGS INC | 0.83%1.64M shares |
VANGUARD PORTFOLIO MANAGEMENT LLC | 0.78%1.54M shares |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0.72%1.43M shares |
Percentages use 197.63M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Feb 4, 2025Form 4 · 10b5-1 | HASTINGS DAVID CChief Financial Officer | SellCommon Shares | 22.2K | $3.28 | $72.8K | 159.7K |
| Feb 4, 2025Form 4 · 10b5-1 | Sims KarenChief Medical Officer | SellCommon Shares | 19.3K | $3.28 | $63.5K | 106.2K |
| Feb 4, 2025Form 4 · 10b5-1 | McElhaugh Michael J.Interim President & CEO | SellCommon Shares | 23.8K | $3.28 | $78.0K | 1.48M |
| Feb 4, 2025Form 4 · 10b5-1 | Naftzger J. ChristopherGeneral Counsel and CCO | SellCommon Shares | 11.3K | $3.28 | $37.2K | 86.2K |
| Aug 14, 2024Form 4 | MANCHESTER KEITH SDirector | SellCommon Shares | 8.8K | $3.69 | $32.6K | 46.1K |