Revenue
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | — |
| Research & development | $60.0M | $64.0M | $46.0M | $23.9M | — |
| Operating expenses | $84.1M | $89.2M | $67.1M | $32.7M | $16.2M |
| Operating income | −$84.1M | −$89.2M | −$67.1M | −$32.7M | −$16.2M |
| EBITDA | −$82.8M | −$88.2M | −$66.6M | −$32.3M | −$16.1M |
| Net income | −$77.9M | −$80.6M | −$60.4M | −$31.2M | −$16.2M |
| Basic EPSper basic share | -$2.02 | -$2.38 | -$2.74 | -$7.56 | -$9.32 |
| Diluted EPSper diluted share | -$2.02 | -$2.38 | -$2.74 | -$7.56 | -$9.32 |
Reported shareholders
| Holder | % owned |
|---|---|
RA CAPITAL MANAGEMENT, L.P. | 28.54%12.23M shares |
PERCEPTIVE ADVISORS LLC / EDELMAN JOSEPH / PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | ≈7.24%3.1M shares |
Masson Kristina / Blume-Jensen Peter | ≈6.14%2.63M shares |
Sands Capital Alternatives, LLC | 5.34%2.29M shares |
ACADIAN ASSET MANAGEMENT LLC | 2.72%1.17M shares |
VANGUARD CAPITAL MANAGEMENT LLC | 2.22%952.01K shares |
WELLINGTON MANAGEMENT GROUP LLP | 2.07%888.13K shares |
RENAISSANCE TECHNOLOGIES LLC | 1.77%758.86K shares |
TWO SIGMA INVESTMENTS, LP | 1.50%641.5K shares |
MARSHALL WACE, LLP | 1.24%531.86K shares |
BRIDGEWAY CAPITAL MANAGEMENT, LLC | 0.88%378.9K shares |
GEODE CAPITAL MANAGEMENT, LLC | 0.62%265.24K shares |
BlackRock, Inc. | 0.56%239.11K shares |
GSA CAPITAL PARTNERS LLP | 0.47%200.42K shares |
VANGUARD FIDUCIARY TRUST CO | 0.43%184.13K shares |
XTX Topco Ltd | 0.42%178.24K shares |
Devroe Eric | ≈0.34%146.95K shares |
Miller Mary | ≈0.19%82.77K shares |
JANE STREET GROUP, LLC | 0.17%74.65K shares |
NORTHERN TRUST CORP | 0.16%67.2K shares |
Percentages use 42.85M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Jan 14, 2026Form 4 | Blume-Jensen Peter +1President and CEO | BuyCommon Stock | 49.0K | $1.68 | $82.3K | 2.10M |
| Jan 14, 2026Form 4 | Levy Adam D.Chief Financial Officer | BuyCommon Stock | 8.8K | $1.70 | $15.0K | 21.0K |
| Jan 13, 2026Form 4 | Devroe EricChief Operating Officer | BuyCommon Stock | 10.0K | $1.72 | $17.2K | 75.3K |
| May 1, 2025Form 4 | PERCEPTIVE ADVISORS LLC +2TenPercentOwner | SellCommon Stock · indirect | 298.9K | $1.34 | $400.5K | 3.10M |
| Apr 30, 2025Form 4 | PERCEPTIVE ADVISORS LLC +2TenPercentOwner | SellCommon Stock · indirect | 437.9K | $1.41 | $617.4K | 3.40M |