Revenue
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
| 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $178.0M | $60.3M | $27.1M | $6.1M | $4.0M | $1.1M | $59.5M | $37.8M | $14.2M | $9.9M | $825,000 |
| Gross profit | $178.0M | $60.3M | $27.1M | — | — | — | — | — | — | — | — |
| Gross margin | 99.96% | 100.00% | 100.00% | — | — | — | — | — | — | — | — |
| Research & development | $149.1M | $126.5M | $127.7M | $111.1M | $91.6M | $97.5M | $98.3M | $87.4M | $63.8M | $24.1M | $9.6M |
| Operating expenses | $246.8M | $200.0M | $191.1M | $168.4M | $137.4M | $140.9M | $141.9M | $118.5M | $87.0M | $34.5M | $12.3M |
| Operating income | −$68.8M | −$139.7M | −$164.0M | −$162.2M | −$133.4M | −$139.8M | −$82.4M | −$80.7M | −$72.8M | −$24.6M | −$11.5M |
| Operating margin | −38.62% | −231.82% | −603.97% | −2,638.58% | −3,370.52% | −12,457.22% | −138.42% | −213.20% | −512.74% | −249.63% | −1,396.48% |
| EBITDA | −$57.5M | −$129.9M | −$157.9M | −$155.7M | −$125.8M | −$131.8M | −$74.6M | −$75.2M | −$69.5M | −$23.9M | −$11.3M |
| EBITDA margin | −32.32% | −215.49% | −581.59% | −2,531.78% | −3,178.65% | −11,743.32% | −125.29% | −198.87% | −489.60% | −242.18% | −1,367.39% |
| Net income | −$70.8M | −$113.9M | −$165.5M | −$158.1M | −$130.1M | −$137.2M | −$95.5M | −$70.1M | −$71.6M | −$22.1M | −$11.6M |
| Net profit margin | −39.78% | −188.90% | −609.46% | −2,570.99% | −3,286.81% | −12,225.04% | −160.51% | −185.39% | −504.15% | −223.46% | −1,406.18% |
| Basic EPSper basic share | -$0.05 | -$0.09 | -$0.17 | -$0.17 | -$0.15 | -$0.22 | -$0.16 | -$0.13 | -$0.17 | -$0.17 | -$0.08 |
| Diluted EPSper diluted share | -$0.05 | -$0.09 | -$0.17 | -$0.17 | -$0.15 | -$0.22 | -$0.16 | -$0.13 | -$0.17 | -$0.17 | -$0.08 |
Reported shareholders
Reported holdings Number of shares
| Holder | Shares held |
|---|---|
EcoR1 Capital, LLC | 358.67M |
Bertrand William C JR | 986.35K |
Bars compare reported share counts. A matching total for this share class and reporting period is unavailable, so percentages are not shown.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Sep 2, 2025Form 4 | Wood GavinChief Financial Officer | SellOrdinary Shares with a nominal value of GBP0.001 per share | 96.0K | $0.01 | $960.00 | 0 |
| Aug 28, 2025Form 4 | Bertrand William C JRChief Operating Officer | SellOrdinary Shares with a nominal value of GBP0.001 per share | 207.0K | $0.01 | $2.1K | 986.4K |
| Aug 18, 2025Form 4 | Behbahani AliDirector | SellOrdinary Shares with a nominal value of 0.001 GBP per share · indirect | 14.67M | $0.01 | $146.7K | 0 |
| Aug 15, 2025Form 4 | Behbahani AliDirector | SellOrdinary Shares with a nominal value of 0.001 GBP per share · indirect | 4.83M | $0.01 | $48.3K | 14.67M |
| Jul 30, 2025Form 4 | EcoR1 Capital, LLCTenPercentOwner | SellOrdinary Shares · indirect | 27.43M | $0.10 | $2.74M | 100.37M |