Revenue
2018
2019
2020
2021
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $54.0M | $36.5M | $26.8M | $14.2M | $0 | $0 | $117.9M | $94.4M | $43.0M | $69.9M | $59.1M | $65.4M | $25.5M | $25.1M | $21.8M |
| Research & development | $339.5M | $301.3M | $295.5M | $279.9M | $257.0M | $220.8M | $214.3M | $341.3M | $292.7M | $220.2M | $141.8M | $100.4M | $54.5M | $41.0M | $31.3M |
| Operating expenses | — | — | — | — | — | — | — | $456.9M | $363.8M | $270.9M | $177.8M | $119.5M | $64.4M | $48.1M | $38.5M |
| Operating income | −$472.1M | −$425.7M | −$391.5M | −$389.0M | −$378.4M | −$335.9M | −$316.3M | −$362.5M | −$320.8M | −$201.0M | −$118.7M | −$54.1M | −$38.9M | −$23.0M | −$16.6M |
| EBITDAderived | — | — | — | — | — | — | −$308.2M | −$355.3M | −$314.4M | — | — | — | — | — | — |
| Net income | −$412.8M | $673.7M | −$352.1M | −$231.8M | $1.60B | −$327.4M | −$411.5M | −$346.0M | −$314.7M | −$198.5M | −$117.7M | −$53.5M | −$39.4M | −$20.1M | −$23.7M |
| Basic EPSper diluted share | -$7.12 | $11.86 | -$6.33 | -$4.23 | $26.55 | -$4.74 | -$6.86 | -$6.03 | -$6.75 | -$5.07 | -$3.15 | -$1.59 | -$2.83 | -$8.02 | -$8.90 |
| Diluted EPSper diluted share | -$7.12 | $11.64 | -$6.33 | -$4.23 | $26.55 | -$4.74 | -$6.86 | -$6.03 | -$6.75 | -$5.07 | -$3.15 | -$1.59 | -$2.83 | -$8.02 | -$8.90 |
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Apr 2, 2026Form 4 · 10b5-1 | Burns James WilliamChief Legal Officer | SellCommon stock | 3.3K | $34.71 | $113.8K | 49.3K |
| Apr 2, 2026Form 4 · 10b5-1 | Gheuens SarahChief Medical Officer | SellCommon stock | 2.9K | $34.71 | $102.0K | 80.3K |
| Apr 2, 2026Form 4 · 10b5-1 | Jones CeciliaChief Financial Officer | SellCommon stock | 3.1K | $34.71 | $109.0K | 55.0K |
| Apr 2, 2026Form 4 · 10b5-1 | Milanova TsvetaChief Commercial Officer | SellCommon stock | 3.3K | $34.71 | $113.2K | 46.8K |
| Apr 2, 2026Form 4 · 10b5-1 | Viswanadhan KrishnanChief Corp Dev & Strategy | SellCommon stock | 3.0K | $34.71 | $102.7K | 10.3K |