Revenue
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $41,000 | $20,000 | $426,000 | −$68,000 | $4.4M | $8.2M | $5.8M | $10.3M | $10.7M | $3.2M | $10.6M | $10.2M | $17.9M | $25.2M | $24.3M | $21.0M |
| Research & development | $66.4M | $82.2M | $65.8M | $70.5M | $74.5M | $49.8M | $17.8M | $18.5M | $18.4M | $7.2M | $5.1M | $9.3M | $15.3M | $19.5M | $21.2M | $20.9M |
| Operating expenses | $94.5M | $103.2M | $96.4M | $87.7M | $101.3M | $63.0M | $27.3M | $53.2M | $62.8M | $14.3M | $14.0M | $20.4M | $28.8M | $31.4M | $36.0M | $44.5M |
| Operating income | −$94.5M | −$103.2M | −$95.9M | −$87.7M | −$96.9M | −$54.8M | −$21.5M | −$42.8M | −$52.0M | −$11.1M | −$3.4M | −$10.2M | −$10.8M | −$6.3M | −$11.7M | −$23.6M |
| Operating margin | −230,460.98% | −515,860.00% | −22,518.54% | — | −2,197.42% | −669.50% | −370.00% | −414.61% | −484.67% | −342.74% | −31.98% | −100.01% | −60.51% | −24.89% | −48.32% | −112.19% |
| EBITDA | −$94.4M | −$102.9M | −$95.5M | −$87.2M | −$96.4M | −$54.4M | −$21.1M | −$42.6M | −$52.0M | −$11.0M | −$3.3M | −$10.0M | −$10.7M | −$6.0M | −$11.3M | −$22.5M |
| EBITDA margin | −230,187.80% | −514,670.00% | −22,406.57% | — | −2,184.92% | −664.26% | −363.32% | −412.50% | −483.89% | −340.79% | −30.65% | −98.54% | −59.49% | −23.68% | −46.42% | −107.33% |
| Net income | −$88.1M | −$95.1M | −$88.4M | −$84.7M | −$97.1M | −$49.0M | −$20.5M | −$39.2M | −$46.4M | −$11.1M | −$3.4M | −$10.0M | −$11.7M | −$4.9M | −$3.8M | −$34.8M |
| Net profit margin | −214,860.98% | −475,295.00% | −20,762.21% | — | −2,201.41% | −599.20% | −353.71% | −379.16% | −432.33% | −342.59% | −32.34% | −97.70% | −65.42% | −19.54% | −15.65% | −166.00% |
| Basic EPSper basic share | -$1.00 | -$1.34 | -$1.66 | -$1.81 | -$2.35 | -$1.91 | -$1.60 | -$15.16 | -$118.91 | $99.00 | -$1.67 | -$5.67 | -$7.67 | -$3.33 | -$2.67 | -$36.00 |
| Diluted EPSper diluted share | -$1.00 | -$1.34 | -$1.66 | -$1.81 | -$2.35 | -$1.91 | -$1.60 | -$15.16 | -$118.91 | $98.33 | -$1.67 | -$5.67 | -$7.67 | -$3.33 | -$2.67 | -$36.00 |
Reported shareholders
| Holder | % owned |
|---|---|
BlackRock, Inc. | 10.48%20.39M shares |
Deep Track Capital, LP | 9.90%19.25M shares |
STATE STREET CORP | 6.22%12.1M shares |
TCG Crossover Management, LLC | 5.14%10M shares |
VANGUARD CAPITAL MANAGEMENT LLC | 4.21%8.18M shares |
VANGUARD PORTFOLIO MANAGEMENT LLC | 3.77%7.33M shares |
MARSHALL WACE, LLP | 3.52%6.84M shares |
VIKING GLOBAL INVESTORS LP | 3.45%6.7M shares |
RA CAPITAL MANAGEMENT, L.P. | 3.34%6.5M shares |
GEODE CAPITAL MANAGEMENT, LLC | 2.58%5.01M shares |
Woodline Partners LP | 1.75%3.4M shares |
MILLENNIUM MANAGEMENT LLC | 1.70%3.31M shares |
Nantahala Capital Management, LLC | 1.54%3M shares |
Trails Edge Capital Partners, LP | 1.37%2.66M shares |
Nuveen, LLC | 1.24%2.41M shares |
TWO SIGMA INVESTMENTS, LP | 1.22%2.38M shares |
GOLDMAN SACHS GROUP INC | 1.14%2.21M shares |
GREAT POINT PARTNERS LLC | 0.90%1.74M shares |
NORTHERN TRUST CORP | 0.82%1.6M shares |
Weiss Asset Management LP | 0.79%1.53M shares |
Percentages use 194.47M shares of this listed class outstanding on Jun 30, 2026.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Apr 6, 2026Form 4 | GILL JOHNDirector | BuyCommon Stock, par value $0.0001 | 9.2K | $3.41 | $31.4K | 21.7K |
| Apr 1, 2026Form 4 | Durso Jerome BenedictPresident and CEO | BuyCommon Stock, par value $0.0001 | 15.0K | $3.14 | $47.1K | 47.5K |
| Apr 1, 2026Form 4 | WEAVER GREGORY LChief Financial Officer | BuyCommon Stock, par value $0.0001 | 10.0K | $3.15 | $31.5K | 38.1K |
| Mar 6, 2026Form 4 | Durso Jerome BenedictPresident and CEO | BuyCommon Stock, par value $0.0001 | 20.0K | $3.54 | $70.8K | 32.5K |
| Mar 6, 2026Form 4 | WEAVER GREGORY LChief Financial Officer | BuyCommon Stock, par value $0.0001 | 5.0K | $3.54 | $17.7K | 28.1K |