Annexon Return on Equity (ROE) Growth & History (ANNX)
Annexon's return on equity was −81.90% for fiscal 2025.
View full Annexon company overviewAnnexon annual return on equity history
| Fiscal year | Period ended | Return on equity | Change (percentage points) |
|---|---|---|---|
| 2025 | 2025-12-31 | −81.90% | −31.06 pp |
| 2024 | 2024-12-31 | −50.84% | +4.89 pp |
| 2023 | 2023-12-31 | −55.73% | +5.57 pp |
| 2022 | 2022-12-31 | −61.30% | −16.07 pp |
| 2021 | 2021-12-31 | −45.24% | +6.78 pp |
| 2020 | 2020-12-31 | −52.01% | — |
Annexon quarterly return on equity
| Fiscal quarter | Period ended | Return on equity | Change (percentage points) |
|---|---|---|---|
| Q2 2026 | 2026-06-30 | −28.34% | −6.14 pp |
| Q1 2026 | 2026-03-31 | −21.21% | −0.96 pp |
| Q4 2025 | 2025-12-31 | −25.87% | −10.31 pp |
| Q3 2025 | 2025-09-30 | −30.47% | −20.42 pp |
| Q2 2025 | 2025-06-30 | −22.20% | −12.70 pp |
| Q1 2025 | 2025-03-31 | −20.25% | −10.43 pp |
| Q4 2024 | 2024-12-31 | −15.56% | −1.86 pp |
| Q3 2024 | 2024-09-30 | −10.06% | +8.96 pp |
| Q2 2024 | 2024-06-30 | −9.50% | +8.11 pp |
| Q1 2024 | 2024-03-31 | −9.82% | +7.53 pp |
| Q4 2023 | 2023-12-31 | −13.69% | +0.29 pp |
| Q3 2023 | 2023-09-30 | −19.02% | −2.66 pp |
| Q2 2023 | 2023-06-30 | −17.61% | +2.53 pp |
| Q1 2023 | 2023-03-31 | −17.34% | −0.98 pp |
| Q4 2022 | 2022-12-31 | −13.98% | +1.07 pp |
| Q3 2022 | 2022-09-30 | −16.36% | −3.64 pp |
| Q2 2022 | 2022-06-30 | −20.15% | −10.00 pp |
| Q1 2022 | 2022-03-31 | −16.36% | −8.53 pp |
| Q4 2021 | 2021-12-31 | −15.06% | −8.52 pp |
| Q3 2021 | 2021-09-30 | −12.72% | −0.09 pp |
| Q2 2021 | 2021-06-30 | −10.15% | — |
| Q1 2021 | 2021-03-31 | −7.83% | — |
| Q4 2020 | 2020-12-31 | −6.54% | — |
| Q3 2020 | 2020-09-30 | −12.63% | — |
Annexon return on equity trends
Over the last five fiscal years, Annexon's return on equity decreased from −52.01% to −81.90%, a change of −29.88 percentage points. The latest reported quarter, Q2 2026, shows −28.34%.
What return on equity (ROE) means
Return on equity (ROE) measures how much net income a company generates relative to shareholders’ equity. It can help evaluate how efficiently equity capital is used, but unusually high or negative values may reflect leverage, losses, or a small equity base.
How return on equity is calculated
TickerStat calculates ROE as SEC-reported net income divided by average stockholders’ equity at the beginning and end of the fiscal period. Periods with missing or non-positive average equity are omitted. Quarterly ROE uses quarterly net income and is not annualized. Fiscal periods can differ from calendar years, so exact period-end dates are included.
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