Annovis Bio Return on Equity (ROE) Growth & History (ANVS)
Annovis Bio's return on equity was −220.61% for fiscal 2025.
View full Annovis Bio company overviewAnnovis Bio annual return on equity history
| Fiscal year | Period ended | Return on equity | Change (percentage points) |
|---|---|---|---|
| 2025 | 2025-12-31 | −220.61% | +2938.49 pp |
| 2024 | 2024-12-31 | −3,159.09% | −2612.69 pp |
| 2023 | 2023-12-31 | −546.40% | −476.83 pp |
| 2022 | 2022-12-31 | −69.57% | −13.89 pp |
| 2021 | 2021-12-31 | −55.68% | — |
Annovis Bio quarterly return on equity
| Fiscal quarter | Period ended | Return on equity | Change (percentage points) |
|---|---|---|---|
| Q1 2026 | 2026-03-31 | −176.26% | −143.07 pp |
| Q4 2025 | 2025-12-31 | −65.55% | +6.10 pp |
| Q3 2025 | 2025-09-30 | −46.13% | +429.64 pp |
| Q2 2025 | 2025-06-30 | −29.35% | — |
| Q1 2025 | 2025-03-31 | −33.19% | — |
| Q4 2024 | 2024-12-31 | −71.65% | — |
| Q3 2024 | 2024-09-30 | −475.77% | −368.35 pp |
| Q3 2023 | 2023-09-30 | −107.42% | −89.86 pp |
| Q2 2023 | 2023-06-30 | −46.66% | −32.07 pp |
| Q1 2023 | 2023-03-31 | −40.19% | −28.18 pp |
| Q4 2022 | 2022-12-31 | −24.56% | −11.56 pp |
| Q3 2022 | 2022-09-30 | −17.56% | −11.57 pp |
| Q2 2022 | 2022-06-30 | −14.59% | −5.06 pp |
| Q1 2022 | 2022-03-31 | −12.01% | +41.73 pp |
| Q4 2021 | 2021-12-31 | −13.00% | +7.47 pp |
| Q3 2021 | 2021-09-30 | −5.99% | +4.82 pp |
| Q2 2021 | 2021-06-30 | −9.53% | +13.35 pp |
| Q1 2021 | 2021-03-31 | −53.73% | −11.99 pp |
| Q4 2020 | 2020-12-31 | −20.46% | — |
| Q3 2020 | 2020-09-30 | −10.81% | — |
| Q2 2020 | 2020-06-30 | −22.88% | — |
| Q1 2020 | 2020-03-31 | −41.75% | — |
Annovis Bio return on equity trends
Between the periods ended 2021-12-31 and 2025-12-31, Annovis Bio's return on equity decreased from −55.68% to −220.61%, a change of −164.93 percentage points. The latest reported quarter, Q1 2026, shows −176.26%.
What return on equity (ROE) means
Return on equity (ROE) measures how much net income a company generates relative to shareholders’ equity. It can help evaluate how efficiently equity capital is used, but unusually high or negative values may reflect leverage, losses, or a small equity base.
How return on equity is calculated
TickerStat calculates ROE as SEC-reported net income divided by average stockholders’ equity at the beginning and end of the fiscal period. Periods with missing or non-positive average equity are omitted. Quarterly ROE uses quarterly net income and is not annualized. Fiscal periods can differ from calendar years, so exact period-end dates are included.
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