Revenue
2012
2013
2014
2015
2017
2018
2019
2020
2021
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $407.3M | $333.6M | $124.5M | $52.2M | $10.1M | $7.6M | $5.3M | $2.6M | $42.0M | — | $24.0M | $31.6M | $28.9M | $5.4M |
| Gross profit | $367.8M | $283.1M | $106.7M | $48.0M | $9.1M | $7.4M | $4.7M | $2.1M | $33.6M | — | $24.0M | — | — | — |
| Gross margin | 90.29% | 84.85% | 85.70% | 92.11% | 90.10% | 98.08% | 88.64% | 82.13% | 80.00% | — | 100.00% | — | — | — |
| Research & development | $71.5M | $52.3M | $35.5M | $35.2M | $91.1M | $65.1M | $71.7M | $69.4M | $75.5M | $94.2M | $39.9M | $25.9M | $28.1M | $10.2M |
| Operating expenses | $448.3M | $361.6M | $187.7M | $115.9M | $164.4M | $98.4M | $96.5M | $93.6M | $98.7M | $112.9M | $53.4M | $33.2M | $31.8M | $14.2M |
| Operating income | −$41.0M | −$27.9M | −$63.3M | −$63.8M | −$154.3M | −$90.8M | −$91.3M | −$90.9M | −$65.1M | −$112.9M | −$29.4M | −$1.6M | −$2.9M | −$8.8M |
| Operating margin | −10.06% | −8.38% | −50.84% | −122.24% | −1,528.63% | −1,199.05% | −1,728.14% | −3,488.57% | −155.04% | — | −122.32% | −4.95% | −9.90% | −162.75% |
| EBITDA | −$37.9M | −$25.9M | −$62.0M | −$62.6M | −$151.5M | −$88.2M | −$88.8M | −$88.2M | −$62.5M | −$111.6M | −$28.6M | −$1.3M | −$2.3M | −$8.1M |
| EBITDA margin | −9.31% | −7.76% | −49.80% | −120.05% | −1,500.83% | −1,165.49% | −1,680.80% | −3,385.00% | −148.85% | — | −118.99% | −4.00% | −7.83% | −150.28% |
| Net income | −$61.6M | −$39.1M | −$66.1M | −$67.2M | −$158.2M | −$94.3M | −$94.9M | −$91.3M | −$64.3M | −$112.4M | −$29.6M | −$3.2M | −$6.6M | −$9.8M |
| Net profit margin | −15.12% | −11.73% | −53.08% | −128.85% | −1,566.46% | −1,245.71% | −1,797.77% | −3,502.03% | −153.19% | — | −123.29% | −10.16% | −22.69% | −180.87% |
| Basic EPSper basic share | -$0.26 | -$0.17 | -$0.30 | -$0.42 | -$1.52 | -$1.05 | -$1.47 | -$1.62 | -$1.36 | -$2.80 | -$1.29 | -$0.31 | -$5.82 | -$11.32 |
| Diluted EPSper diluted share | -$0.26 | -$0.17 | -$0.30 | -$0.42 | -$1.52 | -$1.05 | -$1.47 | -$1.62 | -$1.36 | -$2.80 | -$1.29 | -$0.31 | -$5.82 | -$11.32 |
Reported shareholders
| Holder | % owned |
|---|---|
BlackRock, Inc. | 9.43%23.5M shares |
Rubric Capital Management LP | 6.50%16.2M shares |
MILLENNIUM MANAGEMENT LLC | 5.58%13.9M shares |
STATE STREET CORP | 5.36%13.36M shares |
VANGUARD CAPITAL MANAGEMENT LLC | 4.20%10.47M shares |
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 3.83%9.55M shares |
VANGUARD PORTFOLIO MANAGEMENT LLC | 3.22%8.03M shares |
GEODE CAPITAL MANAGEMENT, LLC | 2.57%6.4M shares |
Jupiter Topco LLC | 2.13%5.3M shares |
TWO SIGMA INVESTMENTS, LP | 2.09%5.21M shares |
Nuveen, LLC | 1.60%4M shares |
GOLDMAN SACHS GROUP INC | 1.48%3.69M shares |
MOTT DAVID M | ≈1.34%3.35M shares |
AIGH Capital Management LLC | 1.28%3.2M shares |
MORGAN STANLEY | 0.96%2.39M shares |
AQR CAPITAL MANAGEMENT LLC | 0.93%2.32M shares |
NORTHERN TRUST CORP | 0.92%2.28M shares |
Rock Springs Capital Management LP | 0.90%2.24M shares |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0.89%2.21M shares |
BANK OF AMERICA CORP /DE/ | 0.87%2.16M shares |
Percentages use 249.15M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Jun 18, 2026Form 4 · 10b5-1 | Williams Laura AChief Patient Officer | SellCommon Stock | 81.9K | $5.99 | $490.6K | 378.2K |
| Jun 15, 2026Form 4 · 10b5-1 | RAAB MICHAELPresident & CEO | SellCommon Stock | 41.7K | $5.67 | $236.2K | 1.70M |
| May 21, 2026Form 4 | Hohenleitner SusanChief Financial Officer | SellCommon Stock | 1.5K | $6.27 | $9.1K | 229.1K |
| May 21, 2026Form 4 | Brady James ParkerChief Human Resources Officer | SellCommon Stock | 1.8K | $6.27 | $11.6K | 261.1K |
| May 21, 2026Form 4 | Reilly Joseph JamesSee Remarks | SellCommon Stock | 1.0K | $6.27 | $6.5K | 149.8K |