Revenue
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $72.3M | $28.5M | $7.2M | $0 | $6.3M | $79.1M | $16.0M | $14.8M | $9.0M | $0 | — | — | — | — | — | — | — | — | — |
| Research & development | $64.8M | $55.9M | $48.9M | $70.0M | $68.5M | $106.8M | $85.8M | $72.7M | $44.2M | $33.1M | $18.4M | $10.7M | $15.0M | $19.5M | $25.3M | $1.9M | $2.9M | — | — |
| Operating expenses | $84.4M | $73.9M | $71.8M | $94.1M | $138.9M | $143.9M | $118.7M | $107.5M | $61.2M | $45.3M | $29.7M | $24.0M | $19.6M | — | — | — | — | — | — |
| Operating income | −$12.1M | −$45.4M | −$64.6M | −$94.1M | −$132.7M | −$64.8M | −$102.7M | −$92.7M | −$52.2M | −$45.3M | −$29.7M | −$24.0M | −$19.6M | −$24.9M | −$34.0M | −$4.8M | −$3.3M | — | — |
| Operating margin | −16.76% | −159.26% | −902.50% | — | −2,121.65% | −81.89% | −643.44% | −626.42% | −579.08% | — | — | — | — | — | — | — | — | — | — |
| EBITDA | −$12.0M | −$45.3M | −$64.2M | −$93.6M | −$132.2M | −$64.1M | −$102.2M | −$92.1M | −$52.0M | −$45.2M | −$29.6M | −$23.9M | −$19.6M | −$24.9M | −$34.0M | −$4.8M | −$3.3M | — | — |
| EBITDA margin | −16.58% | −158.80% | −896.22% | — | −2,114.20% | −81.01% | −640.35% | −622.08% | −576.65% | — | — | — | — | — | — | — | — | — | — |
| Net income | −$6.1M | −$40.2M | −$61.2M | −$93.1M | −$129.9M | −$62.2M | −$97.6M | −$90.8M | −$42.8M | −$44.3M | −$28.5M | −$23.8M | −$19.4M | −$24.8M | −$34.3M | −$15.3M | −$4.5M | −$8.8M | −$4.6M |
| Net profit margin | −8.47% | −140.87% | −854.78% | — | −2,076.35% | −78.57% | −611.63% | −613.02% | −474.65% | — | — | — | — | — | — | — | — | — | — |
| Basic EPSper basic share | -$0.55 | -$6.69 | -$13.38 | -$23.08 | -$5,190.23 | -$3,027.63 | -$6,435.88 | -$6,885.70 | -$4,169.48 | -$4,446.29 | -$3,131.44 | -$5,882.26 | -$8,650.38 | -$16,781.73 | -$30,881.84 | -$213,404.78 | -$86,676.77 | — | — |
| Diluted EPSper diluted share | -$0.55 | -$6.69 | -$13.38 | -$23.08 | -$5,190.23 | -$3,027.63 | -$6,435.88 | -$6,885.70 | -$4,169.48 | -$4,446.29 | -$3,131.44 | -$5,882.26 | -$8,650.38 | -$16,781.73 | -$30,881.84 | -$213,404.78 | -$86,676.77 | — | — |
Reported shareholders
| Holder | % owned |
|---|---|
GILEAD SCIENCES, INC. | 25.07%4.98M shares |
FARALLON CAPITAL MANAGEMENT, L.L.C. | 8.08%1.6M shares |
Paradigm Biocapital Advisors LP | 7.83%1.55M shares |
Commodore Capital LP | 7.13%1.42M shares |
RA CAPITAL MANAGEMENT, L.P. | 5.14%1.02M shares |
Jupiter Topco LLC | 4.28%849.31K shares |
BlackRock, Inc. | 3.86%766.82K shares |
Schornstein Alexander | ≈3.67%728.11K shares |
Parkman Healthcare Partners LLC | 3.63%721.18K shares |
VANGUARD CAPITAL MANAGEMENT LLC | 2.82%558.94K shares |
Point72 Asset Management, L.P. | 2.32%460.59K shares |
Seven Fleet Capital Management LP | 2.18%433.15K shares |
MILLENNIUM MANAGEMENT LLC | 1.51%298.81K shares |
GEODE CAPITAL MANAGEMENT, LLC | 1.41%280.42K shares |
Schonfeld Strategic Advisors LLC | 1.22%242.15K shares |
AMERIPRISE FINANCIAL INC | 1.16%230K shares |
DV EQUITIES, LLC | 1.14%226.42K shares |
Aberdeen Group plc | 1.04%207.05K shares |
Affinity Asset Advisors, LLC | 0.96%190K shares |
B Group, Inc. | 0.89%175.71K shares |
Percentages use 19.85M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Jun 17, 2026Form 4 | Bjorkquist Jeanette MPFO and PAO | SellCommon Stock | 29 | $23.25 | $674.25 | 14.6K |
| Mar 30, 2026Form 4 | Bjorkquist Jeanette MPFO and PAO | SellCommon Stock | 16 | $27.49 | $439.84 | 11.1K |
| Mar 30, 2026Form 4 | Bjorkquist Jeanette MPFO and PAO | SellCommon Stock | 312 | $26.65 | $8.3K | 11.1K |
| Mar 30, 2026Form 4 | White Nicole SChief Manufacturing Officer | SellCommon Stock | 9 | $27.49 | $247.41 | 37.5K |
| Mar 30, 2026Form 4 | White Nicole SChief Manufacturing Officer | SellCommon Stock | 188 | $26.65 | $5.0K | 37.5K |