Revenue
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | |
|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | — | — | — |
| Research & development | $62.0M | $118.1M | $102.5M | $62.7M | $28.0M | $3.7M | $1.1M |
| Operating expenses | $83.5M | $144.1M | $126.1M | $83.6M | $41.7M | $5.3M | $1.2M |
| Operating income | −$83.5M | −$144.1M | −$126.1M | −$83.6M | −$41.7M | −$5.3M | −$1.2M |
| EBITDA | −$82.1M | −$142.3M | −$124.6M | −$82.9M | −$41.4M | −$5.3M | −$1.2M |
| Net income | −$61.8M | −$138.4M | −$117.3M | −$81.8M | −$41.6M | −$5.3M | −$1.2M |
| Basic EPSper basic share | -$1.18 | -$3.83 | -$3.44 | -$2.80 | -$1.74 | -$0.51 | -$0.20 |
| Diluted EPSper diluted share | -$1.18 | -$3.83 | -$3.44 | -$2.80 | -$1.74 | -$0.51 | -$0.20 |
Reported shareholders
| Holder | % owned |
|---|---|
FMR LLC | 12.16%8.81M shares |
Chen Bihua / Cormorant Asset Management, LP / Cormorant Global Healthcare Master Fund, LP / Cormorant Private Healthcare Fund III LP | ≈4.93%3.57M shares |
VANGUARD CAPITAL MANAGEMENT LLC | 3.90%2.83M shares |
Erdtmann Rainer M | ≈3.65%2.64M shares |
MARSHALL WACE, LLP | 2.83%2.05M shares |
Aisling Capital Management LP | 2.83%2.05M shares |
RENAISSANCE TECHNOLOGIES LLC | 2.01%1.46M shares |
FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A. | 1.00%723.18K shares |
BlackRock, Inc. | 0.99%715.45K shares |
GEODE CAPITAL MANAGEMENT, LLC | 0.98%708.85K shares |
SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0.85%612.74K shares |
Mariner, LLC | 0.82%594.73K shares |
JANE STREET GROUP, LLC | 0.63%458.29K shares |
UBS Group AG | 0.61%444.73K shares |
XTX Topco Ltd | 0.56%406.88K shares |
TWO SIGMA INVESTMENTS, LP | 0.53%384.46K shares |
MORGAN STANLEY | 0.51%367.02K shares |
VANGUARD FIDUCIARY TRUST CO | 0.47%338.35K shares |
MAI Capital Management | 0.40%289.1K shares |
STATE STREET CORP | 0.35%257.32K shares |
Percentages use 72.48M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Dec 11, 2025Form 4 | Erdtmann Rainer MSee Remarks | BuyCommon Stock | 30.0K | $1.43 | $42.9K | 723.0K |
| Dec 2, 2025Form 4 | Hitchcock Michael J.M.Interim CEO | BuyCommon Stock | 100.0K | $0.99 | $99.0K | 115.0K |
| Dec 1, 2025Form 4 | Erdtmann Rainer MSee Remarks | BuyCommon Stock | 10.0K | $1.05 | $10.5K | 693.0K |
| Nov 28, 2025Form 4 | Erdtmann Rainer MSee Remarks | BuyCommon Stock | 40.0K | $1.10 | $44.0K | 683.0K |
| Sep 30, 2024Form 4 | Hitchcock Michael J.M.Director | BuyCommon Stock | 10.0K | $10.06 | $100.6K | 15.0K |