Revenue
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $379.8M | $333.8M | $280.3M | $321.8M | $296.4M | $192.2M | $127.1M | $76.6M | $48.3M | $40.6M | $28.1M | $27.3M | $22.1M | $20.5M |
| Gross profit | $256.6M | $224.1M | $178.3M | $209.6M | — | — | $81.6M | $43.6M | $27.0M | $30.4M | $28.1M | $27.3M | $13.0M | $12.5M |
| Gross margin | 67.55% | 67.14% | 63.59% | 65.13% | — | — | 64.23% | 56.92% | 55.78% | 74.80% | 100.00% | 100.00% | 58.92% | 61.22% |
| Research & development | $71.4M | $72.5M | $82.4M | $90.4M | $76.5M | $48.9M | $30.7M | $14.5M | $12.4M | $12.4M | $9.3M | $3.8M | $3.2M | $4.8M |
| Operating expenses | $410.6M | $293.0M | $483.7M | $399.0M | $326.1M | $214.7M | $151.6M | $92.1M | $47.2M | $78.0M | $40.1M | $26.1M | $23.0M | $22.8M |
| Operating income | −$30.8M | $40.8M | −$203.4M | −$77.2M | −$29.7M | −$22.5M | −$24.5M | −$15.6M | −$20.3M | −$37.3M | −$11.9M | $1.3M | −$857,000 | −$2.3M |
| Operating margin | −8.10% | 12.21% | −72.55% | −24.00% | −10.03% | −11.72% | −19.31% | −20.35% | −42.00% | −91.88% | −42.40% | 4.58% | −3.88% | −11.45% |
| EBITDA | −$15.8M | $55.0M | −$189.0M | −$65.6M | −$20.9M | −$15.5M | −$19.0M | −$11.4M | −$16.6M | −$34.4M | −$11.1M | $1.8M | −$194,000 | −$1.3M |
| EBITDA margin | −4.15% | 16.47% | −67.41% | −20.40% | −7.06% | −8.08% | −14.96% | −14.84% | −34.28% | −84.69% | −39.57% | 6.45% | −0.88% | −6.21% |
| Net income | −$21.4M | $52.5M | −$190.3M | −$76.6M | −$30.7M | −$18.7M | −$22.0M | −$46.8M | −$55.5M | −$39.5M | −$13.7M | $781,000 | −$3.5M | −$5.1M |
| Net profit margin | −5.62% | 15.74% | −67.88% | −23.81% | −10.34% | −9.74% | −17.29% | −61.06% | −114.79% | −97.14% | −48.70% | 2.86% | −16.03% | −24.74% |
| Basic EPSper basic share | -$0.40 | $1.00 | -$3.54 | -$1.44 | -$0.59 | -$0.40 | -$0.52 | -$1.31 | -$2.38 | -$2.39 | -$1.16 | $0.13 | -$3.50 | -$34.32 |
| Diluted EPSper diluted share | -$0.40 | $0.93 | -$3.54 | -$1.44 | -$0.59 | -$0.40 | -$0.52 | -$1.31 | -$2.38 | -$2.39 | -$1.16 | $0.10 | -$3.50 | -$34.32 |
Reported shareholders
| Holder | % owned |
|---|---|
BlackRock, Inc. | 9.35%4.81M shares |
STATE STREET CORP | 4.80%2.47M shares |
VANGUARD CAPITAL MANAGEMENT LLC | 4.27%2.2M shares |
DEERFIELD MANAGEMENT COMPANY, L.P. | 3.88%2M shares |
ARK Investment Management LLC | 3.79%1.95M shares |
Boston Partners | 3.76%1.94M shares |
BAMCO INC /NY/ | 3.76%1.94M shares |
GAGNON SECURITIES LLC | 3.44%1.77M shares |
Chevy Chase Trust Holdings, LLC | 2.79%1.44M shares |
GEODE CAPITAL MANAGEMENT, LLC | 2.58%1.33M shares |
Ophir Asset Management Pty Ltd | 2.46%1.26M shares |
RENAISSANCE TECHNOLOGIES LLC | 2.41%1.24M shares |
BRAIDWELL LP | 2.37%1.22M shares |
First Eagle Investment Management, LLC | 2.33%1.2M shares |
Sumitomo Mitsui Trust Group, Inc. | 2.31%1.19M shares |
Blue Water Life Science Advisors, LP | 2.31%1.19M shares |
Amova Asset Management Americas, Inc. | 2.31%1.19M shares |
DIMENSIONAL FUND ADVISORS LP | 2.29%1.18M shares |
D. E. Shaw & Co., Inc. | 2.21%1.14M shares |
JACOBS LEVY EQUITY MANAGEMENT, INC | 1.93%995.67K shares |
Percentages use 51.48M shares of this listed class outstanding on Jun 30, 2026.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Jun 29, 2026Form 4 · 10b5-1 | Hanna John Walter JRPresident and CEO | SellCommon Stock | 39.9K | $29.24 | $1.17M | 662.0K |
| Jun 26, 2026Form 4 · 10b5-1 | Hanna John Walter JRPresident and CEO | SellCommon Stock | 100 | $29.00 | $2.9K | 662.0K |
| Jun 15, 2026Form 4 · 10b5-1 | Hanna John Walter JRPresident and CEO | SellCommon Stock | 17.7K | $24.03 | $424.9K | 632.0K |
| Jun 15, 2026Form 4 · 10b5-1 | Valantine HannahDirector | SellCommon Stock | 12.1K | $23.11 | $279.7K | 36.7K |
| Jun 11, 2026Form 4 · 10b5-1 | Hanna John Walter JRPresident and CEO | SellCommon Stock | 22.0K | $24.02 | $528.4K | 649.6K |