Revenue
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | |
|---|---|---|---|---|---|---|---|
| Revenue | $64,000 | $26.0M | $0 | — | — | — | — |
| Research & development | $37.8M | $29.3M | $53.0M | $96.6M | $80.5M | — | — |
| Operating expenses | $58.1M | $48.5M | $69.1M | $116.5M | — | — | — |
| Operating income | −$58.1M | −$22.5M | −$69.1M | −$119.3M | −$98.1M | — | — |
| Operating margin | −90,740.63% | −86.24% | — | — | — | — | — |
| EBITDA | −$57.4M | −$21.8M | −$68.3M | −$118.3M | −$97.5M | — | — |
| EBITDA margin | −89,640.63% | −83.71% | — | — | — | — | — |
| Net income | −$55.5M | −$15.6M | −$62.1M | −$118.1M | −$202.3M | — | — |
| Net profit margin | −86,687.50% | −60.03% | — | — | — | — | — |
| Basic EPSper basic share | -$1.00 | -$0.28 | -$1.13 | -$2.15 | -$3.88 | — | — |
| Diluted EPSper diluted share | -$1.00 | -$0.28 | -$1.13 | -$2.15 | -$3.88 | — | — |
Reported shareholders
| Holder | % owned |
|---|---|
Huang James | ≈21.14%13.31M shares |
Ikarian Capital, LLC | 7.21%4.54M shares |
683 Capital Management, LLC | 2.04%1.29M shares |
BOOTHBAY FUND MANAGEMENT, LLC | 1.55%973.73K shares |
BlackRock, Inc. | 1.38%871.65K shares |
PERCEPTIVE ADVISORS LLC | 1.26%792.7K shares |
ADAR1 Capital Management, LLC | 1.11%700K shares |
BML Capital Management, LLC | 0.91%573.29K shares |
SILVERARC CAPITAL MANAGEMENT, LLC | 0.87%545K shares |
Richmond Brothers, Inc. | 0.85%535.61K shares |
Knott David M Jr | 0.71%444.86K shares |
Stonepine Capital Management, LLC | 0.58%364.25K shares |
MARSHALL WACE, LLP | 0.53%335.64K shares |
GEODE CAPITAL MANAGEMENT, LLC | 0.41%257.45K shares |
Quart Barry D | ≈0.36%224.03K shares |
Szekeres David Leslie | ≈0.34%215.74K shares |
TWO SIGMA INVESTMENTS, LP | 0.32%199.38K shares |
DIADEMA PARTNERS LP | 0.31%196.99K shares |
Burkehill Global Management, LP | 0.24%150K shares |
VANGUARD PORTFOLIO MANAGEMENT LLC | 0.16%102.76K shares |
Percentages use 62.97M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| May 29, 2026Form 4 | Huang JamesDirector | BuyOrdinary Shares · indirect | 150.0K | $2.48 | $372.0K | 13.31M |
| Mar 31, 2026Form 4 | Huang JamesDirector | BuyOrdinary Shares · indirect | 1.16M | $3.45 | $4.00M | 13.16M |