Denali Therapeutics annual operating margin
2018
2019
2020
2021
2022
2023
Denali Therapeutics Operating Margin Growth & History (DNLI)
Denali Therapeutics's operating margin was −59.51% for fiscal 2023.
View full Denali Therapeutics company overviewDenali Therapeutics annual operating margin history
| Fiscal year | Period ended | Operating margin | Change (percentage points) |
|---|---|---|---|
| 2023 | 2023-12-31 | −59.51% | +264.81 pp |
| 2022 | 2022-12-31 | −324.32% | +283.51 pp |
| 2021 | 2021-12-31 | −607.83% | −626.52 pp |
| 2020 | 2020-12-31 | 18.69% | +828.66 pp |
| 2019 | 2019-12-31 | −809.97% | −774.05 pp |
| 2018 | 2018-12-31 | −35.92% | — |
Denali Therapeutics quarterly operating margin
Q1.18
Q2.18
Q3.18
Q4.18
Q1.19
Q2.19
Q3.19
Q4.19
Q1.20
Q2.20
Q3.20
Q4.20
Q1.21
Q2.21
Q3.21
Q4.21
Q1.22
Q2.22
Q3.22
Q4.22
Q1.23
Q2.23
Q3.23
Q2.26
| Fiscal quarter | Period ended | Operating margin | Change (percentage points) |
|---|---|---|---|
| Q2 2026 | 2026-06-30 | −3,622.11% | −2595.37 pp |
| Q3 2023 | 2023-09-30 | −8,981.45% | +49434.85 pp |
| Q2 2023 | 2023-06-30 | 57.96% | +174.99 pp |
| Q1 2023 | 2023-03-31 | −343.80% | −186.00 pp |
| Q4 2022 | 2022-12-31 | −1,026.74% | −410.47 pp |
| Q3 2022 | 2022-09-30 | −58,416.30% | −56796.76 pp |
| Q2 2022 | 2022-06-30 | −117.03% | +152.49 pp |
| Q1 2022 | 2022-03-31 | −157.80% | +741.22 pp |
| Q4 2021 | 2021-12-31 | −616.28% | −693.32 pp |
| Q3 2021 | 2021-09-30 | −1,619.55% | −979.20 pp |
| Q2 2021 | 2021-06-30 | −269.52% | +784.98 pp |
| Q1 2021 | 2021-03-31 | −899.02% | +789.24 pp |
| Q4 2020 | 2020-12-31 | 77.04% | +1331.83 pp |
| Q3 2020 | 2020-09-30 | −640.35% | −269.05 pp |
| Q2 2020 | 2020-06-30 | −1,054.50% | +477.05 pp |
| Q1 2020 | 2020-03-31 | −1,688.26% | −654.25 pp |
| Q4 2019 | 2019-12-31 | −1,254.79% | −1314.27 pp |
| Q3 2019 | 2019-09-30 | −371.30% | +2805.61 pp |
| Q2 2019 | 2019-06-30 | −1,531.55% | +1950.37 pp |
| Q1 2019 | 2019-03-31 | −1,034.01% | +2982.84 pp |
| Q4 2018 | 2018-12-31 | 59.48% | — |
| Q3 2018 | 2018-09-30 | −3,176.90% | — |
| Q2 2018 | 2018-06-30 | −3,481.92% | — |
| Q1 2018 | 2018-03-31 | −4,016.85% | — |
Denali Therapeutics operating margin trends
Over the last five reported fiscal years, Denali Therapeutics's operating margin decreased from −35.92% to −59.51%, a change of −23.59 percentage points. The latest reported quarter, Q2 2026, shows −3,622.11%.
About the metric
What operating margin means
Operating margin measures the percentage of revenue left after operating costs and expenses. It shows how much operating profit a company generates from each dollar of revenue.
Calculation and source
How operating margin is calculated
TickerStat calculates operating margin as SEC-reported operating income divided by SEC-reported revenue for the same fiscal period. Changes are shown in percentage points. Fiscal periods can differ from calendar years, so exact period-end dates are included.
Review Denali Therapeutics filings at SEC.gov ↗