Revenue
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | |
|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | — | — | — |
| Research & development | $398.3M | $281.4M | $210.8M | $142.8M | $121.3M | $45.2M | $11.0M |
| Operating expenses | $468.2M | $343.9M | $242.2M | $171.0M | $150.0M | $58.6M | $13.8M |
| Operating income | −$468.2M | −$343.9M | −$242.2M | −$171.0M | −$150.0M | −$58.6M | −$13.8M |
| EBITDA | −$466.1M | −$342.2M | −$240.5M | −$169.3M | −$148.9M | −$57.9M | −$13.6M |
| Net income | −$446.2M | −$317.4M | −$235.9M | −$168.1M | −$149.3M | −$59.4M | −$14.9M |
| Basic EPSper basic share | -$3.47 | -$3.37 | -$3.95 | -$3.23 | -$2.93 | -$4.13 | -$6.08 |
| Diluted EPSper diluted share | -$3.47 | -$3.37 | -$3.95 | -$3.23 | -$2.93 | -$4.13 | -$6.08 |
Reported shareholders
| Holder | % owned |
|---|---|
T. Rowe Price Investment Management, Inc. | 18.66%30.91M shares |
BlackRock, Inc. | 7.49%12.4M shares |
Jupiter Topco LLC | 7.24%12M shares |
FMR LLC | 6.76%11.21M shares |
STATE STREET CORP | 4.50%7.46M shares |
Orbis Allan Gray Ltd | 4.23%7.01M shares |
Rhodes Jason P | ≈4.11%6.81M shares |
Atlas Venture Life Science Advisors, LLC | 4.10%6.8M shares |
VANGUARD CAPITAL MANAGEMENT LLC | 3.81%6.31M shares |
TCG Crossover Management, LLC | 2.79%4.62M shares |
VANGUARD PORTFOLIO MANAGEMENT LLC | 2.44%4.05M shares |
PRICE T ROWE ASSOCIATES INC /MD/ | 2.38%3.94M shares |
Kersten Dirk | ≈2.32%3.85M shares |
FCPM III SERVICES B.V. | 2.32%3.85M shares |
GEODE CAPITAL MANAGEMENT, LLC | 2.26%3.74M shares |
Vestal Point Capital, LP | 2.04%3.38M shares |
ORBIMED ADVISORS LLC | 1.95%3.24M shares |
Frazier Life Sciences Management, L.P. | 1.90%3.15M shares |
JPMORGAN CHASE & CO | 1.90%3.15M shares |
ARMISTICE CAPITAL, LLC | 1.86%3.09M shares |
Percentages use 165.67M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Jun 29, 2026Form 4 · 10b5-1 | Rhodes Jason PDirector | SellCommon Stock · indirect | 40.7K | $21.14 | $860.4K | 975.9K |
| Jun 29, 2026Form 4 · 10b5-1 | Rhodes Jason PDirector | SellCommon Stock · indirect | 51.8K | $21.14 | $1.09M | 1.34M |
| Jun 29, 2026Form 4 · 10b5-1 | Rhodes Jason PDirector | SellCommon Stock · indirect | 103.0K | $21.14 | $2.18M | 4.48M |
| Jun 26, 2026Form 4 · 10b5-1 | Rhodes Jason PDirector | SellCommon Stock · indirect | 64.4K | $21.28 | $1.37M | 1.02M |
| Jun 26, 2026Form 4 · 10b5-1 | Rhodes Jason PDirector | SellCommon Stock · indirect | 81.9K | $21.28 | $1.74M | 1.40M |
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