Revenue
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | — | — | — | — | — | — | — | — | — | — |
| Research & development | $82.0M | $80.0M | $83.2M | $71.3M | $61.1M | $38.6M | $22.5M | $9.6M | $39.3M | $30.0M | $39.8M | $39.5M | $21.8M | $5.1M |
| Operating expenses | $103.2M | $98.1M | $99.2M | $119.5M | $91.7M | $49.0M | $37.0M | $12.0M | $52.7M | $41.3M | $52.1M | $50.3M | $31.4M | $9.6M |
| Operating income | −$103.2M | −$98.1M | −$99.2M | −$119.5M | −$91.7M | −$49.0M | −$37.0M | −$12.0M | −$52.7M | −$41.3M | −$52.1M | −$50.3M | −$31.4M | −$9.6M |
| EBITDA | −$103.1M | −$97.9M | −$99.1M | −$119.4M | −$91.6M | −$48.9M | −$37.0M | −$12.0M | −$51.7M | −$39.5M | −$50.8M | −$49.3M | −$30.6M | −$8.9M |
| Net income | −$97.2M | −$100.5M | −$93.6M | −$120.4M | −$92.9M | −$44.0M | −$34.9M | −$11.5M | −$52.1M | −$41.0M | −$52.0M | −$47.7M | −$32.7M | −$6.7M |
| Basic EPSper basic share | -$0.62 | -$1.00 | -$2.11 | -$3.78 | -$3.93 | -$2.81 | -$4.52 | -$13.63 | -$2,620.00 | -$2,620.00 | -$4,140.00 | -$7,080.00 | -$149,720.00 | -$35,780.00 |
| Diluted EPSper diluted share | -$0.62 | -$1.00 | -$2.11 | -$3.78 | -$3.93 | -$2.81 | -$4.52 | -$13.63 | -$2,620.00 | -$2,620.00 | -$4,140.00 | -$7,080.00 | -$149,720.00 | -$35,780.00 |
Reported shareholders
| Holder | % owned |
|---|---|
Aberdeen Group plc | 6.04%824.39K shares |
BVF INC/IL | 5.61%765.3K shares |
MILLENNIUM MANAGEMENT LLC | 5.43%740.35K shares |
Avidity Partners Management LP | 4.91%669.94K shares |
BRAIDWELL LP | 4.73%645.01K shares |
Laurion Capital Management LP | 4.47%610.33K shares |
VANGUARD CAPITAL MANAGEMENT LLC | 4.19%571.56K shares |
Jones Hill Capital LP | 3.96%539.81K shares |
Nantahala Capital Management, LLC | 3.67%501.29K shares |
Woodline Partners LP | 3.46%471.53K shares |
Soleus Capital Management, L.P. | 3.30%450K shares |
Vitt Daniel | ≈2.87%391.88K shares |
Propel Bio Management, LLC | 2.38%325.02K shares |
Rudick Richard Alan | ≈1.69%230.38K shares |
Neermann Joerg | ≈1.47%200K shares |
UBS Group AG | 1.29%175.76K shares |
GEODE CAPITAL MANAGEMENT, LLC | 1.25%170.68K shares |
683 Capital Management, LLC | 1.08%147.25K shares |
ADAGE CAPITAL PARTNERS GP, L.L.C. | 1.03%139.86K shares |
BlackRock, Inc. | 0.97%132.79K shares |
Percentages use 13.64M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Jun 13, 2025Form 4 | Nash DuaneExecutive Chairman | BuyCommon Stock | 20.0K | $0.83 | $16.6K | 36.0K |
| Jun 5, 2025Form 4/A | Tardio JasonPresident and COO | BuyCommon Stock | 12.5K | $0.79 | $9.9K | 12.5K |
| Jun 5, 2025Form 4 | Tardio JasonPresident and COO | BuyCommon Stock | 12.5K | $0.79 | $9.9K | 12.5K |
| Jun 5, 2025Form 4 | Neermann JoergDirector | BuyCommon Stock | 30.0K | $0.76 | $22.8K | 200.0K |
| Jun 4, 2025Form 4/A | Vitt DanielCEO and Director | BuyCommon Stock | 15.0K | $0.77 | $11.6K | 29.0K |