Revenue
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | |
|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | — | — |
| Research & development | $10.2M | $17.0M | $16.8M | $14.1M | $7.3M | $5.4M |
| Operating expenses | $19.9M | $30.7M | $30.3M | $28.5M | $14.7M | $8.6M |
| Operating income | −$19.4M | −$30.4M | −$30.0M | −$28.5M | −$14.7M | −$8.6M |
| EBITDA | −$17.7M | −$28.6M | −$28.2M | −$27.9M | −$14.0M | −$8.5M |
| Net income | −$19.4M | −$30.4M | −$30.0M | −$28.5M | −$14.7M | −$8.6M |
| Basic EPSper basic share | -$4.44 | -$17.05 | -$30.00 | -$40.80 | -$44.10 | -$90.60 |
| Diluted EPSper diluted share | -$4.44 | -$17.05 | -$30.00 | -$40.80 | -$44.10 | -$90.60 |
Reported shareholders
| Holder | % owned |
|---|---|
BIOS Fund III NT, LP / BP Directors, LP / BIOS Fund III, LP / BIOS Fund III QP, LP / Kreis Leslie W. / Bios Equity Partners II, LP / BIOS Equity Partners III, LP / Bios Equity Partners, LP / Cavu Management, LP / Cavu Advisors, LLC | ≈87.28%8.6M shares |
Alyeska Investment Group, L.P. | 9.58%944.32K shares |
FRANKLIN RESOURCES INC | 9.28%914.53K shares |
683 Capital Management, LLC | 7.35%724.64K shares |
Stonepine Capital Management, LLC | 7.06%695.29K shares |
Ho William Tai-Wei | —124.82K shares |
Brandt Peter C. | —98.69K shares |
VANGUARD CAPITAL MANAGEMENT LLC | 0.90%88.87K shares |
BIOS Capital Management, LP | 0.82%80.96K shares |
GEODE CAPITAL MANAGEMENT, LLC | 0.74%72.55K shares |
CITADEL ADVISORS LLC | 0.64%63.06K shares |
OPPENHEIMER & CO INC | 0.64%63.04K shares |
Roemer Alan S. | —49.51K shares |
VANGUARD FIDUCIARY TRUST CO | 0.44%43.57K shares |
CAPTRUST FINANCIAL ADVISORS | 0.34%33.3K shares |
Texas Capital Bank Wealth Management Services Inc | 0.25%24.41K shares |
NORTHERN TRUST CORP | 0.22%21.73K shares |
RENAISSANCE TECHNOLOGIES LLC | 0.12%12.1K shares |
McCall Patrick | —9.48K shares |
Rochlin Kate | —9.09K shares |
Percentages use 9.85M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.
Reported positions exceed 100% in total, so the circle shows the selected holder only.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| May 2, 2025Form 4 | BIOS Fund II, LP +8TenPercentOwner | BuyPre-Funded Warrants · derivative · indirect | 1.15M | — | — | 2.43M |
| May 2, 2025Form 4 | BIOS Fund III NT, LP +9TenPercentOwner | BuyPre-Funded Warrants · derivative · indirect | 1.15M | — | — | 2.43M |
| Oct 4, 2024Form 4 | BP Directors, LP +9TenPercentOwner | BuySeries C Warrant · derivative · indirect | 709.0K | — | — | 709.0K |
| Oct 4, 2024Form 4 | BP Directors, LP +9TenPercentOwner | BuyPre-Funded Warrants · derivative · indirect | 709.0K | — | — | 1.28M |
| Oct 4, 2024Form 4 | BIOS Fund II QP, LP +8TenPercentOwner | BuySeries C Warrant · derivative · indirect | 709.0K | — | — | 709.0K |