Revenue
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | |
|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | — | — |
| Research & development | $170.6M | $96.7M | $69.3M | $33.4M | $25.2M | $28.2M |
| Operating expenses | $236.0M | $129.7M | $91.1M | $47.5M | $30.9M | $34.0M |
| Operating income | −$236.0M | −$129.7M | −$91.1M | −$47.5M | −$30.9M | −$34.0M |
| EBITDA | −$235.7M | −$129.6M | −$91.0M | −$47.4M | −$30.9M | −$33.7M |
| Net income | −$212.2M | −$109.4M | −$76.4M | −$46.8M | −$36.0M | −$40.8M |
| Basic EPSper basic share | -$6.01 | -$3.96 | -$3.42 | -$45.05 | -$40.95 | -$2.70 |
| Diluted EPSper diluted share | -$6.01 | -$3.96 | -$3.42 | -$45.05 | -$40.95 | -$2.70 |
Reported shareholders
| Holder | % owned |
|---|---|
FMR LLC | 12.76%4.89M shares |
AI DMI LLC / ACCESS INDUSTRIES MANAGEMENT, LLC / Blavatnik Len / Access Industries Holdings LLC | ≈7.34%2.81M shares |
BlackRock, Inc. | 6.44%2.47M shares |
RA CAPITAL MANAGEMENT, L.P. | 6.39%2.45M shares |
JPMORGAN CHASE & CO | 4.89%1.88M shares |
PRICE T ROWE ASSOCIATES INC /MD/ | 4.89%1.88M shares |
WELLINGTON MANAGEMENT GROUP LLP | 4.54%1.74M shares |
STATE STREET CORP | 4.30%1.65M shares |
Vestal Point Capital, LP | 4.04%1.55M shares |
Atlas Venture Life Science Advisors, LLC | 3.95%1.51M shares |
ORBIMED ADVISORS LLC / OrbiMed Capital GP VI LLC / OrbiMed Genesis GP LLC / OrbiMed Capital GP VIII LLC | ≈3.69%1.42M shares |
Ashiya Mona | ≈3.69%1.42M shares |
VANGUARD CAPITAL MANAGEMENT LLC | 3.57%1.37M shares |
Frazier Life Sciences Management, L.P. | 3.53%1.35M shares |
TCG Crossover Management, LLC | 3.50%1.34M shares |
BVF INC/IL | 3.01%1.15M shares |
Woodline Partners LP | 2.50%958.28K shares |
Siren, L.L.C. | 2.32%888.4K shares |
Logos Global Management LP | 2.28%875K shares |
Opaleye Management Inc. | 2.23%855K shares |
Percentages use 38.35M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Jun 29, 2026Form 4 · 10b5-1 | Khara RahulChief Legal Officer | SellCommon Stock | 1.6K | $75.00 | $123.7K | 52.2K |
| Jun 26, 2026Form 4 · 10b5-1 | Khara RahulChief Legal Officer | SellCommon Stock | 851 | $75.00 | $63.8K | 52.2K |
| Jun 26, 2026Form 4 · 10b5-1 | Yu Jonathan Yen-WenChief Operating Officer | SellCommon Stock | 300 | $72.50 | $21.8K | 54.3K |
| Jun 22, 2026Form 4 · 10b5-1 | Yu Jonathan Yen-WenChief Operating Officer | SellCommon Stock | 9.7K | $72.66 | $704.8K | 54.3K |
| Jun 18, 2026Form 4 · 10b5-1 | Khara RahulChief Legal Officer | SellCommon Stock | 500 | $71.62 | $35.8K | 52.2K |