International Stem Cell annual operating margin
2010
2011
2012
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2014
2015
2016
2017
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2019
2020
2021
2022
2023
2024
2025
International Stem Cell Operating Margin Growth & History (ISCO)
International Stem Cell's operating margin was −2.93% for fiscal 2025.
View full International Stem Cell company overviewInternational Stem Cell annual operating margin history
| Fiscal year | Period ended | Operating margin | Change (percentage points) |
|---|---|---|---|
| 2025 | 2025-12-31 | −2.93% | −2.19 pp |
| 2024 | 2024-12-31 | −0.75% | +7.76 pp |
| 2023 | 2023-12-31 | −8.51% | −6.27 pp |
| 2022 | 2022-12-31 | −2.24% | +24.53 pp |
| 2021 | 2021-12-31 | −26.77% | +12.76 pp |
| 2020 | 2020-12-31 | −39.53% | +20.94 pp |
| 2019 | 2019-12-31 | −60.47% | −29.14 pp |
| 2018 | 2018-12-31 | −31.33% | +34.95 pp |
| 2017 | 2017-12-31 | −66.28% | +1.42 pp |
| 2016 | 2016-12-31 | −67.70% | −7.26 pp |
| 2015 | 2015-12-31 | −60.44% | +63.26 pp |
| 2014 | 2014-12-31 | −123.70% | −0.94 pp |
| 2013 | 2013-12-31 | −122.76% | +92.15 pp |
| 2012 | 2012-12-31 | −214.91% | +35.64 pp |
| 2011 | 2011-12-31 | −250.55% | +416.67 pp |
| 2010 | 2010-12-31 | −667.22% | — |
International Stem Cell quarterly operating margin
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Q2.26
| Fiscal quarter | Period ended | Operating margin | Change (percentage points) |
|---|---|---|---|
| Q2 2026 | 2026-06-30 | −1.31% | −8.13 pp |
| Q1 2026 | 2026-03-31 | −8.21% | +1.89 pp |
| Q4 2025 | 2025-12-31 | −14.52% | −16.61 pp |
| Q3 2025 | 2025-09-30 | 3.97% | +8.10 pp |
| Q2 2025 | 2025-06-30 | 6.82% | +0.43 pp |
| Q1 2025 | 2025-03-31 | −10.10% | −1.74 pp |
| Q4 2024 | 2024-12-31 | 2.09% | +24.53 pp |
| Q3 2024 | 2024-09-30 | −4.13% | +0.79 pp |
| Q2 2024 | 2024-06-30 | 6.39% | +14.21 pp |
| Q1 2024 | 2024-03-31 | −8.36% | −8.46 pp |
| Q4 2023 | 2023-12-31 | −22.45% | −24.96 pp |
| Q3 2023 | 2023-09-30 | −4.92% | +12.70 pp |
| Q2 2023 | 2023-06-30 | −7.82% | −9.35 pp |
| Q1 2023 | 2023-03-31 | 0.10% | −1.14 pp |
| Q4 2022 | 2022-12-31 | 2.51% | +20.14 pp |
| Q3 2022 | 2022-09-30 | −17.62% | +16.21 pp |
| Q2 2022 | 2022-06-30 | 1.53% | +23.68 pp |
| Q1 2022 | 2022-03-31 | 1.24% | +35.44 pp |
| Q4 2021 | 2021-12-31 | −17.63% | +32.06 pp |
| Q3 2021 | 2021-09-30 | −33.82% | +20.06 pp |
| Q2 2021 | 2021-06-30 | −22.15% | +23.77 pp |
| Q1 2021 | 2021-03-31 | −34.20% | −14.92 pp |
| Q4 2020 | 2020-12-31 | −49.69% | +37.90 pp |
| Q3 2020 | 2020-09-30 | −53.88% | −15.09 pp |
| Q2 2020 | 2020-06-30 | −45.92% | −5.37 pp |
| Q1 2020 | 2020-03-31 | −19.28% | +47.85 pp |
| Q4 2019 | 2019-12-31 | −87.59% | −30.96 pp |
| Q3 2019 | 2019-09-30 | −38.79% | −18.04 pp |
| Q2 2019 | 2019-06-30 | −40.54% | −28.46 pp |
| Q1 2019 | 2019-03-31 | −67.13% | −22.13 pp |
| Q4 2018 | 2018-12-31 | −56.64% | +47.82 pp |
| Q3 2018 | 2018-09-30 | −20.75% | +31.77 pp |
| Q2 2018 | 2018-06-30 | −12.08% | +44.79 pp |
| Q1 2018 | 2018-03-31 | −45.01% | +7.16 pp |
| Q4 2017 | 2017-12-31 | −104.45% | −35.04 pp |
| Q3 2017 | 2017-09-30 | −52.52% | +12.43 pp |
| Q2 2017 | 2017-06-30 | −56.87% | +8.32 pp |
| Q1 2017 | 2017-03-31 | −52.17% | +20.05 pp |
| Q4 2016 | 2016-12-31 | −69.41% | −16.88 pp |
| Q3 2016 | 2016-09-30 | −64.95% | −35.83 pp |
| Q2 2016 | 2016-06-30 | −65.19% | −13.56 pp |
| Q1 2016 | 2016-03-31 | −72.22% | +48.99 pp |
| Q4 2015 | 2015-12-31 | −52.53% | +76.15 pp |
| Q3 2015 | 2015-09-30 | −29.12% | +74.50 pp |
| Q2 2015 | 2015-06-30 | −51.63% | +89.62 pp |
| Q1 2015 | 2015-03-31 | −121.21% | +4.02 pp |
| Q4 2014 | 2014-12-31 | −128.67% | −16.86 pp |
| Q3 2014 | 2014-09-30 | −103.62% | −1.64 pp |
| Q2 2014 | 2014-06-30 | −141.25% | +9.06 pp |
| Q1 2014 | 2014-03-31 | −125.23% | +8.08 pp |
| Q4 2013 | 2013-12-31 | −111.82% | +95.96 pp |
| Q3 2013 | 2013-09-30 | −101.98% | +73.26 pp |
| Q2 2013 | 2013-06-30 | −150.31% | +79.33 pp |
| Q1 2013 | 2013-03-31 | −133.31% | +119.15 pp |
| Q4 2012 | 2012-12-31 | −207.78% | +66.11 pp |
| Q3 2012 | 2012-09-30 | −175.23% | +195.55 pp |
| Q2 2012 | 2012-06-30 | −229.64% | +26.91 pp |
| Q1 2012 | 2012-03-31 | −252.46% | −89.49 pp |
| Q4 2011 | 2011-12-31 | −273.89% | +568.59 pp |
| Q3 2011 | 2011-09-30 | −370.78% | +275.85 pp |
| Q2 2011 | 2011-06-30 | −256.55% | — |
| Q1 2011 | 2011-03-31 | −162.97% | — |
| Q3 2010 | 2010-09-30 | −842.49% | — |
| Q2 2010 | 2010-06-30 | −646.63% | — |
International Stem Cell operating margin trends
Over the last five reported fiscal years, International Stem Cell's operating margin increased from −39.53% to −2.93%, a change of +36.60 percentage points. The latest reported quarter, Q2 2026, shows −1.31%.
About the metric
What operating margin means
Operating margin measures the percentage of revenue left after operating costs and expenses. It shows how much operating profit a company generates from each dollar of revenue.
Calculation and source
How operating margin is calculated
TickerStat calculates operating margin as SEC-reported operating income divided by SEC-reported revenue for the same fiscal period. Changes are shown in percentage points. Fiscal periods can differ from calendar years, so exact period-end dates are included.
Review International Stem Cell filings at SEC.gov ↗