Krystal Biotech annual operating margin
2023
2024
2025
Krystal Biotech Operating Margin Growth & History (KRYS)
Krystal Biotech's operating margin was 41.45% for fiscal 2025.
View full Krystal Biotech company overviewKrystal Biotech annual operating margin history
| Fiscal year | Period ended | Operating margin | Change (percentage points) |
|---|---|---|---|
| 2025 | 2025-12-31 | 41.45% | +18.82 pp |
| 2024 | 2024-12-31 | 22.63% | +238.84 pp |
| 2023 | 2023-12-31 | −216.21% | — |
Krystal Biotech quarterly operating margin
Q3.23
Q4.23
Q1.24
Q2.24
Q3.24
Q4.24
Q1.25
Q2.25
Q3.25
Q4.25
Q1.26
Q2.26
| Fiscal quarter | Period ended | Operating margin | Change (percentage points) |
|---|---|---|---|
| Q2 2026 | 2026-06-30 | 49.00% | +7.98 pp |
| Q1 2026 | 2026-03-31 | 46.14% | +5.03 pp |
| Q4 2025 | 2025-12-31 | 41.33% | −4.08 pp |
| Q3 2025 | 2025-09-30 | 42.30% | +15.50 pp |
| Q2 2025 | 2025-06-30 | 41.02% | +28.83 pp |
| Q1 2025 | 2025-03-31 | 41.11% | +55.88 pp |
| Q4 2024 | 2024-12-31 | 45.42% | +37.71 pp |
| Q3 2024 | 2024-09-30 | 26.80% | +330.60 pp |
| Q2 2024 | 2024-06-30 | 12.19% | — |
| Q1 2024 | 2024-03-31 | −14.77% | — |
| Q4 2023 | 2023-12-31 | 7.70% | — |
| Q3 2023 | 2023-09-30 | −303.80% | — |
Krystal Biotech operating margin trends
Across the available reported history, Krystal Biotech's operating margin increased from 22.63% to 41.45%, a change of +18.82 percentage points. The latest reported quarter, Q2 2026, shows 49.00%.
About the metric
What operating margin means
Operating margin measures the percentage of revenue left after operating costs and expenses. It shows how much operating profit a company generates from each dollar of revenue.
Calculation and source
How operating margin is calculated
TickerStat calculates operating margin as SEC-reported operating income divided by SEC-reported revenue for the same fiscal period. Changes are shown in percentage points. Fiscal periods can differ from calendar years, so exact period-end dates are included.
Review Krystal Biotech filings at SEC.gov ↗