Revenue
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $67.5M | $53.9M | $0 | $0 | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Research & development | $251.1M | $170.0M | $115.2M | $92.8M | $84.7M | $60.4M | $47.8M | $46.8M | $26.4M | — | — | — | — | — | — | — | — | — | — |
| Operating expenses | $371.1M | $247.1M | $165.8M | $139.9M | $131.3M | $91.9M | $67.5M | $62.9M | $36.1M | $28.4M | $23.9M | — | — | — | — | — | — | — | — |
| Operating income | −$303.6M | −$193.2M | −$165.8M | −$139.9M | — | — | — | — | — | — | — | −$23,907 | −$22,734 | −$22,341 | −$23,440 | −$20,509 | — | — | — |
| Operating margin | −449.94% | −358.55% | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| EBITDA | −$302.6M | −$192.3M | −$165.0M | −$139.1M | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| EBITDA margin | −448.41% | −356.97% | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Net income | −$278.7M | −$174.0M | −$152.6M | −$135.8M | −$130.5M | −$89.6M | −$63.1M | −$60.4M | −$35.4M | −$27.6M | −$22.6M | −$30,734 | −$28,611 | −$27,315 | −$27,040 | −$22,395 | −$19,996 | −$33,623 | −$14,977 |
| Net profit margin | −412.95% | −322.89% | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Basic EPSper basic share | -$3.18 | -$2.02 | -$2.08 | -$2.03 | -$1.97 | -$1.69 | -$1.51 | -$1.72 | -$1.52 | -$1.47 | -$2.28 | -$0.02 | -$0.02 | -$0.02 | -$0.02 | $0.00 | — | — | — |
| Diluted EPSper diluted share | -$3.18 | -$2.02 | -$2.08 | -$2.03 | -$1.97 | -$1.69 | -$1.51 | -$1.72 | -$1.52 | -$1.47 | -$2.28 | -$0.02 | -$0.02 | -$0.02 | -$0.02 | $0.00 | — | — | — |
Reported shareholders
| Holder | % owned |
|---|---|
BlackRock, Inc. | 11.81%10.51M shares |
MONTANOVA CAPITAL, LLC | 9.64%8.58M shares |
BVF INC/IL | 9.49%8.45M shares |
STATE STREET CORP | 5.99%5.33M shares |
VANGUARD CAPITAL MANAGEMENT LLC | 4.40%3.92M shares |
ARMISTICE CAPITAL, LLC | 4.13%3.68M shares |
AQR CAPITAL MANAGEMENT LLC | 3.51%3.13M shares |
GOLDMAN SACHS GROUP INC | 2.55%2.27M shares |
GEODE CAPITAL MANAGEMENT, LLC | 2.51%2.23M shares |
ALETHEA CAPITAL MANAGEMENT, LLC | 2.44%2.17M shares |
Prosight Management, LP | 2.27%2.02M shares |
Deep Track Capital, LP | 2.22%1.98M shares |
RENAISSANCE TECHNOLOGIES LLC | 1.87%1.66M shares |
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 1.59%1.41M shares |
VANGUARD PORTFOLIO MANAGEMENT LLC | 1.50%1.33M shares |
NAN FUNG TRINITY (HK) LTD | 1.32%1.17M shares |
Qube Research & Technologies Ltd | 1.32%1.17M shares |
DIMENSIONAL FUND ADVISORS LP | 1.31%1.17M shares |
BANK OF AMERICA CORP /DE/ | 1.31%1.16M shares |
MORGAN STANLEY | 1.30%1.16M shares |
Percentages use 88.95M shares of this listed class outstanding on Jun 30, 2026.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Jun 18, 2026Form 4 · 10b5-1 | Leoni MollieChief Medical Officer | SellCommon Stock | 84.9K | $9.82 | $834.0K | 182.3K |
| May 21, 2026Form 4 · 10b5-1 | Powl Brian T.Chief Commercial Officer | SellCommon Stock | 10.0K | $11.00 | $110.0K | 173.6K |
| May 19, 2026Form 4 · 10b5-1 | FORD KATHLEENChief Operating Officer | SellCommon Stock | 2.3K | $9.08 | $20.5K | 153.6K |
| May 19, 2026Form 4 · 10b5-1 | Powl Brian T.Chief Commercial Officer | SellCommon Stock | 339 | $9.21 | $3.1K | 183.6K |
| May 18, 2026Form 4 · 10b5-1 | Bair Teresa BrophyChief Legal Officer | SellCommon Stock | 2.3K | $9.38 | $21.2K | 226.9K |