Mirum Pharmaceuticals annual operating margin
2021
2022
2023
2024
2025
Mirum Pharmaceuticals Operating Margin Growth & History (MIRM)
Mirum Pharmaceuticals's operating margin was −4.25% for fiscal 2025.
View full Mirum Pharmaceuticals company overviewMirum Pharmaceuticals annual operating margin history
| Fiscal year | Period ended | Operating margin | Change (percentage points) |
|---|---|---|---|
| 2025 | 2025-12-31 | −4.25% | +21.76 pp |
| 2024 | 2024-12-31 | −26.00% | +32.56 pp |
| 2023 | 2023-12-31 | −58.57% | +111.71 pp |
| 2022 | 2022-12-31 | −170.28% | +735.84 pp |
| 2021 | 2021-12-31 | −906.12% | — |
Mirum Pharmaceuticals quarterly operating margin
Q2.21
Q3.21
Q4.21
Q1.22
Q2.22
Q3.22
Q4.22
Q1.23
Q2.23
Q3.23
Q4.23
Q1.24
Q2.24
Q3.24
Q4.24
Q1.25
Q2.25
Q3.25
Q4.25
Q1.26
Q2.26
| Fiscal quarter | Period ended | Operating margin | Change (percentage points) |
|---|---|---|---|
| Q2 2026 | 2026-06-30 | −24.14% | −20.23 pp |
| Q1 2026 | 2026-03-31 | −493.78% | −480.17 pp |
| Q4 2025 | 2025-12-31 | −3.07% | +21.30 pp |
| Q3 2025 | 2025-09-30 | 1.96% | +15.99 pp |
| Q2 2025 | 2025-06-30 | −3.90% | +27.21 pp |
| Q1 2025 | 2025-03-31 | −13.61% | +24.63 pp |
| Q4 2024 | 2024-12-31 | −24.36% | +22.48 pp |
| Q3 2024 | 2024-09-30 | −14.03% | +38.66 pp |
| Q2 2024 | 2024-06-30 | −31.12% | +33.62 pp |
| Q1 2024 | 2024-03-31 | −38.24% | +47.68 pp |
| Q4 2023 | 2023-12-31 | −46.85% | +75.57 pp |
| Q3 2023 | 2023-09-30 | −52.69% | +122.40 pp |
| Q2 2023 | 2023-06-30 | −64.73% | +115.09 pp |
| Q1 2023 | 2023-03-31 | −85.92% | +168.01 pp |
| Q4 2022 | 2022-12-31 | −122.41% | +1329.94 pp |
| Q3 2022 | 2022-09-30 | −175.09% | +681.39 pp |
| Q2 2022 | 2022-06-30 | −179.83% | +160.18 pp |
| Q1 2022 | 2022-03-31 | −253.92% | — |
| Q4 2021 | 2021-12-31 | −1,452.36% | — |
| Q3 2021 | 2021-09-30 | −856.48% | — |
| Q2 2021 | 2021-06-30 | −340.01% | — |
Mirum Pharmaceuticals operating margin trends
Across the available reported history, Mirum Pharmaceuticals's operating margin increased from −26.00% to −4.25%, a change of +21.76 percentage points. The latest reported quarter, Q2 2026, shows −24.14%.
About the metric
What operating margin means
Operating margin measures the percentage of revenue left after operating costs and expenses. It shows how much operating profit a company generates from each dollar of revenue.
Calculation and source
How operating margin is calculated
TickerStat calculates operating margin as SEC-reported operating income divided by SEC-reported revenue for the same fiscal period. Changes are shown in percentage points. Fiscal periods can differ from calendar years, so exact period-end dates are included.
Review Mirum Pharmaceuticals filings at SEC.gov ↗