Revenue
2019
2021
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | |
|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | $0 | — | $115,000 |
| Research & development | $90.4M | $96.7M | $96.8M | $90.9M | $63.4M | $36.2M | $17.2M |
| Operating expenses | $122.0M | $128.2M | $131.7M | $119.0M | $86.4M | $51.5M | $22.5M |
| Operating income | −$122.0M | −$128.2M | −$131.7M | −$119.0M | −$86.4M | −$51.5M | −$22.3M |
| Operating margin | — | — | — | — | — | — | −19,433.91% |
| EBITDA | −$112.8M | −$119.0M | −$125.8M | −$116.4M | −$84.6M | −$50.7M | −$21.9M |
| EBITDA margin | — | — | — | — | — | — | −19,086.09% |
| Net income | −$104.1M | −$108.8M | −$117.5M | −$113.8M | −$86.1M | −$91.4M | −$21.1M |
| Net profit margin | — | — | — | — | — | — | −18,326.96% |
| Basic EPSper basic share | -$1.41 | -$1.60 | -$2.40 | -$2.61 | -$2.62 | -$5.44 | -$14.41 |
| Diluted EPSper diluted share | -$1.41 | -$1.60 | -$2.40 | -$2.61 | -$2.62 | -$5.44 | -$14.41 |
Reported shareholders
Reported holdings Number of shares
| Holder | Shares held |
|---|---|
RA CAPITAL MANAGEMENT, L.P. | 10.81M |
BlackRock, Inc. | 6.3M |
NEA Management Company, LLC | 3.57M |
SAMSARA BIOCAPITAL, LLC | 3.51M |
SR One Capital Management, LP | 3.33M |
GSK plc | 3.15M |
Monaco Asset Management SAM | 2.37M |
VANGUARD CAPITAL MANAGEMENT LLC | 2.23M |
CITADEL ADVISORS LLC | 2.17M |
TWO SIGMA INVESTMENTS, LP | 1.87M |
WASATCH ADVISORS LP | 1.58M |
ACADIAN ASSET MANAGEMENT LLC | 1.36M |
STATE STREET CORP | 1.29M |
GEODE CAPITAL MANAGEMENT, LLC | 1.29M |
RENAISSANCE TECHNOLOGIES LLC | 1.18M |
AQR CAPITAL MANAGEMENT LLC | 1.05M |
AWM Investment Company, Inc. | 906K |
Blackstone Inc. | 747.04K |
MARSHALL WACE, LLP | 673.01K |
PANAGORA ASSET MANAGEMENT INC | 583.25K |
Bars compare reported share counts. A matching total for this share class and reporting period is unavailable, so percentages are not shown.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Jun 18, 2026Form 4 | HASTINGS PAUL JChief Executive Officer | SellCommon Stock | 1.8K | $2.71 | $4.8K | 390.2K |
| Jan 15, 2026Form 4 | HASTINGS PAUL JChief Executive Officer | SellCommon Stock | 26.0K | $2.07 | $53.9K | 390.0K |
| Jan 15, 2026Form 4 | Mahmood NadirPresident | SellCommon Stock | 5.6K | $2.07 | $11.7K | 167.7K |
| Jun 18, 2025Form 4 | HASTINGS PAUL JChief Executive Officer | SellCommon Stock | 1.8K | $1.79 | $3.2K | 320.1K |
| Jan 15, 2025Form 4 | Shook DavidSee Remarks | SellCommon Stock | 8.6K | $2.20 | $19.0K | 191.0K |