Orchestra BioMed Holdings, Inc. (OBIO)

Price$4.95Cached quote
OBIONasdaq
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Financial charts

Total cash / debt

CashTotal debt

Financial statements

6 annual periodsNewest to oldest
202520242023202220212020
Revenue$33.5M$2.6M$2.8M$3.5M——
Gross profit$33.3M$2.4M$2.6M$3.3M——
Gross margin99.43%92.27%93.26%94.03%——
Research & development$58.2M$42.8M$33.8M$21.9M——
Operating expenses$85.3M$66.9M$54.3M$36.2M—$179,986
Operating income−$51.8M−$64.3M−$51.5M−$32.7M−$394,756—
Operating margin−154.73%−2,437.49%−1,866.16%−924.34%——
EBITDA−$51.5M−$64.0M−$51.2M−$32.4M——
EBITDA margin−153.75%−2,425.82%−1,855.76%−918.06%——
Net income−$52.7M−$61.0M−$49.1M−$33.6M−$378,753−$173,542
Net profit margin−157.40%−2,313.27%−1,779.71%−951.26%——
Basic EPSper basic share-$1.11-$1.66-$1.48-$2.24-$0.02$0.00
Diluted EPSper diluted share-$1.11-$1.66-$1.48-$2.24-$0.02$0.00

Owners

Reported shareholders

Reference date Jun 30, 2026
RTW INVESTMENTS, LP · 15.90% of listed sharesPERCEPTIVE ADVISORS LLC · 8.38% of listed sharesBlackRock, Inc. · 4.18% of listed sharesVANGUARD CAPITAL MANAGEMENT LLC · 3.37% of listed sharesHSAC 2 Holdings, LLC · ≈2.84% of listed sharesHochman David P · ≈2.51% of listed sharesSherman Darren · ≈1.97% of listed sharesGEODE CAPITAL MANAGEMENT, LLC · 1.68% of listed sharesAlyeska Investment Group, L.P. · 1.66% of listed sharesPropel Bio Management, LLC · 1.49% of listed sharesUBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC · 1.07% of listed sharesTaylor Andrew Lawrence · ≈0.99% of listed sharesSTATE STREET CORP · 0.86% of listed sharesRICE HALL JAMES & ASSOCIATES, LLC · 0.71% of listed sharesCHARLES SCHWAB INVESTMENT MANAGEMENT INC · 0.58% of listed sharesNORTHERN TRUST CORP · 0.57% of listed sharesUBS Group AG · 0.54% of listed sharesVANGUARD FIDUCIARY TRUST CO · 0.49% of listed sharesVANGUARD PORTFOLIO MANAGEMENT LLC · 0.46% of listed sharesKnott David M Jr · 0.42% of listed shares
15.90%of listed shares
RTW INVESTMENTS, LP9.56M shares · Jun 30, 2026
View holders
Top 20 reported holders of OBIO
Holder% owned
RTW INVESTMENTS, LP
15.90%9.56M shares
PERCEPTIVE ADVISORS LLC
8.38%5.04M shares
BlackRock, Inc.
4.18%2.51M shares
VANGUARD CAPITAL MANAGEMENT LLC
3.37%2.02M shares
HSAC 2 Holdings, LLC
≈2.84%1.71M shares
Hochman David P
≈2.51%1.51M shares
Sherman Darren
≈1.97%1.18M shares
GEODE CAPITAL MANAGEMENT, LLC
1.68%1.01M shares
Alyeska Investment Group, L.P.
1.66%1M shares
Propel Bio Management, LLC
1.49%896.7K shares
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC
1.07%642.15K shares
Taylor Andrew Lawrence
≈0.99%593.07K shares
STATE STREET CORP
0.86%516.05K shares
RICE HALL JAMES & ASSOCIATES, LLC
0.71%424K shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC
0.58%349.54K shares
NORTHERN TRUST CORP
0.57%343.64K shares
UBS Group AG
0.54%325.77K shares
VANGUARD FIDUCIARY TRUST CO
0.49%292.25K shares
VANGUARD PORTFOLIO MANAGEMENT LLC
0.46%274.97K shares
Knott David M Jr
0.42%253.65K shares

Percentages use 60.11M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.

Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.

Source: SEC Form 13F ↗Updated Sep 29, 2026 · Quarterly data

Insider buys & sells

Jul 1, 2024–Jun 30, 2026
Buys27$16.76M disclosed value
Sells (SEC code S)11$291.9K disclosed value
38 recent transactions
TransactionInsiderTypeSharesPriceValueOwned after
Jun 1, 2026Form 4Hochman David PSee RemarksBuyCommon Stock, par value $0.0001 per share ("Common Stock")5.0K$3.83$19.1K1.06M
Jun 1, 2026Form 4 · 10b5-1Sherman DarrenSee RemarksSellCommon Stock, par value $0.0001 per share15.0K$3.87$58.0K1.18M
May 18, 2026Form 4Aryeh JasonDirectorBuyCommon Stock, par value $0.0001 per share665$3.75$2.5K118.1K
May 15, 2026Form 4Aryeh JasonDirectorBuyCommon Stock, par value $0.0001 per share9.0K$3.90$35.0K117.5K
May 15, 2026Form 4Hochman David PSee RemarksBuyCommon Stock, par value $0.0001 per share ("Common Stock")5.0K$3.77$18.9K1.06M

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