Revenue
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | |
|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | — | — | — |
| Research & development | $23.3M | $40.2M | $61.4M | $86.1M | $117.7M | $81.8M | $29.7M |
| Operating expenses | $43.2M | $65.2M | $103.0M | $135.4M | — | — | — |
| Operating income | −$49.3M | −$70.4M | −$108.4M | −$138.4M | −$185.7M | −$112.9M | −$37.2M |
| EBITDA | −$48.6M | −$67.3M | −$104.7M | −$134.7M | −$184.2M | −$112.1M | −$37.1M |
| Net income | −$45.5M | −$64.8M | −$102.1M | −$136.1M | −$185.4M | −$112.2M | −$45.6M |
| Basic EPSper basic share | -$14.35 | -$21.04 | -$37.20 | -$50.00 | -$69.60 | -$58.20 | -$215.40 |
| Diluted EPSper diluted share | -$14.35 | -$21.04 | -$37.20 | -$50.00 | -$69.60 | -$58.20 | -$215.40 |
Reported shareholders
| Holder | % owned |
|---|---|
ORBIMED ADVISORS LLC / OrbiMed Capital GP VII LLC | —6.07M shares |
CITADEL ADVISORS LLC | 89.69%2.89M shares |
Lynx1 Capital Management LP | 20.94%673.76K shares |
VANGUARD CAPITAL MANAGEMENT LLC | 3.54%113.96K shares |
Balyasny Asset Management L.P. | 3.33%107.03K shares |
Ikarian Capital, LLC | 3.09%99.52K shares |
Yiheng Capital Management, L.P. | 2.68%86.1K shares |
RENAISSANCE TECHNOLOGIES LLC | 1.49%47.89K shares |
Erste Asset Management GmbH | 1.26%40.67K shares |
GEODE CAPITAL MANAGEMENT, LLC | 1.15%37.03K shares |
Verdad Advisers, LP | 0.95%30.73K shares |
BOOTHBAY FUND MANAGEMENT, LLC | 0.88%28.44K shares |
BlackRock, Inc. | 0.87%27.91K shares |
ACADIAN ASSET MANAGEMENT LLC | 0.70%22.5K shares |
VANGUARD FIDUCIARY TRUST CO | 0.53%17.05K shares |
DELTEC ASSET MANAGEMENT LLC | 0.47%15K shares |
UBS Group AG | 0.42%13.57K shares |
HRT FINANCIAL LP | 0.40%12.71K shares |
Fiduciary Trust Co | 0.33%10.75K shares |
GTS SECURITIES LLC | 0.31%10K shares |
Percentages use 3.22M shares of this listed class outstanding on Jun 30, 2026.
Reported positions exceed 100% in total, so the circle shows the selected holder only.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Jun 25, 2026Form 4 | Nichols Weston +1TenPercentOwner | BuyCommon stock, $0.0001 par value per share ("Common Stock") · indirect | 50.1K | $4.12 | $206.2K | 673.8K |
| Jan 8, 2026Form 4 | Borthwick KathleenCFO | SellCommon Stock | 2.1K | $18.44 | $38.0K | 5.4K |
| Jan 8, 2026Form 4 | Chou WilliamPRESIDENT AND CEO | SellCommon Stock | 4.1K | $18.44 | $75.2K | 6.5K |
| Sep 15, 2025Form 4 | Nichols Weston +1TenPercentOwner | BuyCommon Stock · indirect | 11.9K | $6.99 | $83.2K | 623.7K |
| Sep 12, 2025Form 4 | Nichols Weston +1TenPercentOwner | BuyCommon Stock · indirect | 19.8K | $6.99 | $138.3K | 611.8K |