Prime Medicine annual free cash flow
2020
2021
2022
2023
2024
2025
Prime Medicine Free Cash Flow (FCF) History (PRME)
Prime Medicine reported −$167.1M in free cash flow for fiscal 2025, a decrease of $36.9M from the previous fiscal year, with a free cash flow margin of −3607.41%.
View full Prime Medicine company overviewPrime Medicine free cash flow by year
| Fiscal year | Period ended | Free cash flow | Change | Growth | FCF margin |
|---|---|---|---|---|---|
| 2025 | 2025-12-31 | −$167.1M | −$36.9M | — | −3607.41% |
| 2024 | 2024-12-31 | −$130.2M | $44.0M | — | −4363.36% |
| 2023 | 2023-12-31 | −$174.1M | −$26.2M | — | — |
| 2022 | 2022-12-31 | −$147.9M | −$109.7M | — | — |
| 2021 | 2021-12-31 | −$38.2M | −$32.0M | — | — |
| 2020 | 2020-12-31 | −$6.2M | — | — | −118.68% |
Prime Medicine quarterly free cash flow
Q1.22
Q2.22
Q3.22
Q4.22
Q1.23
Q2.23
Q3.23
Q4.23
Q1.24
Q2.24
Q3.24
Q4.24
Q1.25
Q2.25
Q3.25
Q4.25
Q1.26
Q2.26
| Fiscal quarter | Period ended | Free cash flow | Change | YoY growth | FCF margin |
|---|---|---|---|---|---|
| Q2 2026 | 2026-06-30 | −$41.1M | $1.9M | — | — |
| Q1 2026 | 2026-03-31 | −$42.9M | $8.4M | — | — |
| Q4 2025 | 2025-12-31 | −$37.5M | −$52.0M | — | −4480.43% |
| Q3 2025 | 2025-09-30 | −$35.3M | −$8.1M | — | −2880.49% |
| Q2 2025 | 2025-06-30 | −$43.0M | $4.4M | — | −3855.07% |
| Q1 2025 | 2025-03-31 | −$51.3M | $18.8M | — | −3526.75% |
| Q4 2024 | 2024-12-31 | $14.5M | $60.2M | — | +662.12% |
| Q3 2024 | 2024-09-30 | −$27.2M | $14.9M | — | −13009.09% |
| Q2 2024 | 2024-06-30 | −$47.4M | −$4.6M | — | — |
| Q1 2024 | 2024-03-31 | −$70.0M | −$26.5M | — | −11849.58% |
| Q4 2023 | 2023-12-31 | −$45.7M | −$10.2M | — | — |
| Q3 2023 | 2023-09-30 | −$42.1M | −$7.2M | — | — |
| Q2 2023 | 2023-06-30 | −$42.8M | −$17.8M | — | — |
| Q1 2023 | 2023-03-31 | −$43.6M | $8.9M | — | — |
| Q4 2022 | 2022-12-31 | −$35.5M | — | — | — |
| Q3 2022 | 2022-09-30 | −$34.9M | — | — | — |
| Q2 2022 | 2022-06-30 | −$25.0M | — | — | — |
| Q1 2022 | 2022-03-31 | −$52.5M | — | — | — |
Prime Medicine free cash flow growth trends
Over the last five reported fiscal years, free cash flow declined from −$6.2M to −$167.1M, a net decrease of $160.9M. Prime Medicine's latest reported quarter, Q2 2026, generated −$41.1M in free cash flow, an increase of $1.9M year over year.
About the metric
What free cash flow means
Free cash flow is the cash a company generates from operations after capital expenditures. Positive FCF can fund dividends, buybacks, debt repayment, or reinvestment; negative FCF means capital spending exceeded operating cash flow for that period.
Calculation and source
How free cash flow is calculated
TickerStat calculates free cash flow as SEC-reported operating cash flow minus capital expenditures. FCF margin equals free cash flow divided by revenue. Fiscal periods can differ from calendar years, so the tables include exact period-end dates.
Review Prime Medicine filings at SEC.gov ↗