ProQR Therapeutics N.V annual operating margin
2021
2022
2023
2024
2025
ProQR Therapeutics N.V Operating Margin Growth & History (PRQR)
ProQR Therapeutics N.V's operating margin was −273.14% for fiscal 2025.
View full ProQR Therapeutics N.V company overviewProQR Therapeutics N.V annual operating margin history
| Fiscal year | Period ended | Operating margin | Change (percentage points) |
|---|---|---|---|
| 2025 | 2025-12-31 | −273.14% | −111.96 pp |
| 2024 | 2024-12-31 | −161.18% | +327.90 pp |
| 2023 | 2023-12-31 | −489.09% | +1323.91 pp |
| 2022 | 2022-12-31 | −1,812.99% | +2472.40 pp |
| 2021 | 2021-12-31 | −4,285.39% | — |
ProQR Therapeutics N.V quarterly operating margin
Q2.21
Q3.21
Q1.22
Q2.22
Q3.22
Q4.22
Q1.23
Q2.23
Q3.23
Q4.23
Q1.24
Q2.24
Q3.24
Q4.24
Q1.25
Q2.25
Q3.25
Q4.25
| Fiscal quarter | Period ended | Operating margin | Change (percentage points) |
|---|---|---|---|
| Q4 2025 | 2025-12-31 | −194.05% | +40.01 pp |
| Q3 2025 | 2025-09-30 | −391.53% | −164.73 pp |
| Q2 2025 | 2025-06-30 | −320.91% | −263.81 pp |
| Q1 2025 | 2025-03-31 | −239.34% | −57.88 pp |
| Q4 2024 | 2024-12-31 | −234.06% | −43.20 pp |
| Q3 2024 | 2024-09-30 | −226.80% | +312.69 pp |
| Q2 2024 | 2024-06-30 | −57.10% | +674.11 pp |
| Q1 2024 | 2024-03-31 | −181.46% | +1251.97 pp |
| Q4 2023 | 2023-12-31 | −190.86% | +1539.69 pp |
| Q3 2023 | 2023-09-30 | −539.49% | +1895.77 pp |
| Q2 2023 | 2023-06-30 | −731.20% | +971.16 pp |
| Q1 2023 | 2023-03-31 | −1,433.44% | +74.88 pp |
| Q4 2022 | 2022-12-31 | −1,730.56% | −61.17 pp |
| Q3 2022 | 2022-09-30 | −2,435.26% | +2998.08 pp |
| Q2 2022 | 2022-06-30 | −1,702.37% | — |
| Q1 2022 | 2022-03-31 | −1,508.32% | — |
| Q3 2021 | 2021-09-30 | −1,669.38% | — |
| Q2 2021 | 2021-06-30 | −5,433.33% | — |
ProQR Therapeutics N.V operating margin trends
Across the available reported history, ProQR Therapeutics N.V's operating margin decreased from −161.18% to −273.14%, a change of −111.96 percentage points. The latest reported quarter, Q4 2025, shows −194.05%.
About the metric
What operating margin means
Operating margin measures the percentage of revenue left after operating costs and expenses. It shows how much operating profit a company generates from each dollar of revenue.
Calculation and source
How operating margin is calculated
TickerStat calculates operating margin as SEC-reported operating income divided by SEC-reported revenue for the same fiscal period. Changes are shown in percentage points. Fiscal periods can differ from calendar years, so exact period-end dates are included.
Review ProQR Therapeutics N.V filings at SEC.gov ↗