Pyxis Oncology, Inc. (PYXS)

Price$2.90Cached quote
PYXSNasdaq
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Financial charts

Total cash / debt

CashTotal debt

Financial statements

6 annual periodsNewest to oldest
202520242023202220212020
Revenue$13.9M$16.1M$0$0——
Gross profit$11.5M$15.7M$0———
Gross margin82.77%97.06%————
Research & development$73.7M$58.7M$49.6M$86.1M$51.1M$9.0M
Operating expenses$95.9M$105.1M$82.2M$123.5M$69.7M$12.9M
Operating income−$84.4M−$89.5M−$82.2M−$123.5M−$69.7M−$12.9M
Operating margin−609.18%−554.07%————
EBITDA−$79.9M−$86.5M−$80.3M−$122.8M−$69.1M−$12.4M
EBITDA margin−576.63%−535.60%————
Net income−$79.6M−$77.3M−$73.8M−$120.7M−$76.0M−$12.8M
Net profit margin−574.55%−478.95%————
Basic EPSper basic share-$1.28-$1.32-$1.85-$3.65-$8.95-$12.45
Diluted EPSper diluted share-$1.28-$1.32-$1.85-$3.65-$8.95-$12.45

Owners

Reported shareholders

Reference date Jun 30, 2026
GordonMD Global Investments LP · 15.80% of listed sharesPfizer Inc · 11.09% of listed sharesLaurion Capital Management LP · 7.73% of listed sharesConnealy Pamela Ann · ≈3.65% of listed sharesVANGUARD CAPITAL MANAGEMENT LLC · 3.27% of listed sharesAtle Fund Management AB · 1.52% of listed sharesBlackRock, Inc. · 1.37% of listed sharesPalo Alto Investors LP · 1.36% of listed sharesMARSHALL WACE, LLP · 1.31% of listed sharesRENAISSANCE TECHNOLOGIES LLC · 1.22% of listed sharesGEODE CAPITAL MANAGEMENT, LLC · 0.93% of listed sharesWoodline Partners LP · 0.83% of listed sharesWadhane Jitendra · ≈0.81% of listed shares683 Capital Management, LLC · 0.72% of listed sharesJACOBS LEVY EQUITY MANAGEMENT, INC · 0.68% of listed sharesLongaeva Partners L.P. · 0.56% of listed sharesDecheng Capital LLC · 0.52% of listed sharesVANGUARD FIDUCIARY TRUST CO · 0.48% of listed sharesJANE STREET GROUP, LLC · 0.46% of listed sharesSTATE STREET CORP · 0.39% of listed shares
15.80%of listed shares
GordonMD Global Investments LP10.02M shares · Jun 30, 2026
View holders
Top 20 reported holders of PYXS
Holder% owned
GordonMD Global Investments LP
15.80%10.02M shares
Pfizer Inc
11.09%7.03M shares
Laurion Capital Management LP
7.73%4.9M shares
Connealy Pamela Ann
≈3.65%2.31M shares
VANGUARD CAPITAL MANAGEMENT LLC
3.27%2.08M shares
Atle Fund Management AB
1.52%966.46K shares
BlackRock, Inc.
1.37%867.93K shares
Palo Alto Investors LP
1.36%864.28K shares
MARSHALL WACE, LLP
1.31%830.54K shares
RENAISSANCE TECHNOLOGIES LLC
1.22%772.23K shares
GEODE CAPITAL MANAGEMENT, LLC
0.93%591.85K shares
Woodline Partners LP
0.83%524K shares
Wadhane Jitendra
≈0.81%512.88K shares
683 Capital Management, LLC
0.72%459.37K shares
JACOBS LEVY EQUITY MANAGEMENT, INC
0.68%428.61K shares
Longaeva Partners L.P.
0.56%353.58K shares
Decheng Capital LLC
0.52%326.81K shares
VANGUARD FIDUCIARY TRUST CO
0.48%302.99K shares
JANE STREET GROUP, LLC
0.46%290.09K shares
STATE STREET CORP
0.39%248.84K shares

Percentages use 63.43M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.

Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.

Source: SEC Form 13F ↗Updated Sep 29, 2026 · Quarterly data

Insider buys & sells

Jul 1, 2024–Jun 30, 2026
Buys2$174.4K disclosed value
Sells (SEC code S)3$15.9K disclosed value
5 recent transactions
TransactionInsiderTypeSharesPriceValueOwned after
Apr 21, 2025Form 4 · 10b5-1HUMPHREY RACHELDirectorSellCommon Stock13.9K$1.03$14.3K81.3K
Apr 17, 2025Form 4 · 10b5-1HUMPHREY RACHELDirectorSellCommon Stock200$0.97$194.0095.2K
Apr 14, 2025Form 4 · 10b5-1HUMPHREY RACHELDirectorSellCommon Stock1.4K$0.97$1.4K95.4K
Nov 26, 2024Form 4Connealy Pamela AnnCFO & COOBuyCommon Stock · indirect83.4K$1.96$163.5K1.20M
Nov 26, 2024Form 4Connealy Pamela AnnCFO & COOBuyCommon Stock · indirect5.5K$2.00$10.9K1.12M

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