Revenue
2020
2021
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | |
|---|---|---|---|---|---|---|
| Revenue | $1.6M | $1.0M | $0 | $0 | $2.7M | $462,000 |
| Research & development | $20.2M | $26.7M | $39.6M | $36.6M | $26.5M | $12.0M |
| Operating expenses | $39.9M | $54.3M | $66.1M | $63.5M | $54.3M | $17.0M |
| Operating income | −$38.3M | −$53.3M | −$66.1M | −$63.5M | −$51.6M | −$16.5M |
| Operating margin | −2,345.99% | −5,186.19% | — | — | −1,899.12% | −3,580.95% |
| EBITDA | −$37.4M | −$52.3M | −$65.3M | −$62.9M | −$51.1M | −$16.0M |
| EBITDA margin | −2,290.88% | −5,086.19% | — | — | −1,880.82% | −3,453.46% |
| Net income | −$29.7M | −$30.0M | −$34.0M | −$30.6M | −$8.3M | −$16.7M |
| Net profit margin | −1,817.09% | −2,920.04% | — | — | −306.62% | −3,615.37% |
| Basic EPSper basic share | -$0.45 | -$1.05 | -$1.33 | -$1.28 | -$0.43 | — |
| Diluted EPSper diluted share | -$0.45 | -$1.05 | -$1.33 | -$1.28 | -$0.43 | — |
Reported shareholders
| Holder | % owned |
|---|---|
SAMSARA BIOCAPITAL, LLC | 9.22%10.37M shares |
RA CAPITAL MANAGEMENT, L.P. | 7.56%8.5M shares |
AWM Investment Company, Inc. | 6.67%7.5M shares |
VANGUARD CAPITAL MANAGEMENT LLC | 4.06%4.56M shares |
South Cone Investments Limited Partnership | ≈2.11%2.38M shares |
Longaeva Partners L.P. | 2.07%2.33M shares |
Polar Asset Management Partners Inc. | 2.06%2.32M shares |
IMRAN MIR A | ≈1.92%2.16M shares |
Siren, L.L.C. | 1.78%2M shares |
HEIGHTS CAPITAL MANAGEMENT, INC | 0.83%934.58K shares |
GEODE CAPITAL MANAGEMENT, LLC | 0.79%890.62K shares |
CITADEL ADVISORS LLC | 0.57%642K shares |
MARSHALL WACE, LLP | 0.52%586.27K shares |
Imran Talat | ≈0.44%494.75K shares |
Nan Fung Group Holdings Ltd | 0.44%493.58K shares |
JANE STREET GROUP, LLC | 0.43%485.9K shares |
VANGUARD FIDUCIARY TRUST CO | 0.41%458.13K shares |
RENAISSANCE TECHNOLOGIES LLC | 0.38%430.74K shares |
STATE STREET CORP | 0.33%373.14K shares |
BlackRock, Inc. | 0.30%342.11K shares |
Percentages use 112.5M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Oct 23, 2025Form 4 | IMRAN MIR ADirector,TenPercentOwner | BuyClass A Common Stock | 2.08M | $0.61 | $1.27M | 2.08M |
| Oct 23, 2025Form 4 | IMRAN MIR ADirector,TenPercentOwner | BuyWarrant to Purchase Class A Common Stock · derivative | 2.08M | $0.00 | $0.00 | 2.08M |
| Oct 21, 2025Form 4 | South Cone Investments Limited PartnershipTenPercentOwner | SellClass A Common Stock · indirect | 4.00M | $2.77 | $11.08M | 2.38M |
| Oct 20, 2025Form 4 | South Cone Investments Limited PartnershipTenPercentOwner | SellClass A Common Stock · indirect | 1.92M | $2.41 | $4.63M | 6.38M |
| Dec 13, 2024Form 4 | McKinley KateChief Business Officer | BuyClass A Common Stock | 18.0K | $1.67 | $30.0K | 18.0K |