Ultragenyx Pharmaceutical annual operating margin
2016
2017
2018
2019
2020
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2022
2023
2024
2025
Ultragenyx Pharmaceutical Operating Margin Growth & History (RARE)
Ultragenyx Pharmaceutical's operating margin was −79.49% for fiscal 2025.
View full Ultragenyx Pharmaceutical company overviewUltragenyx Pharmaceutical annual operating margin history
| Fiscal year | Period ended | Operating margin | Change (percentage points) |
|---|---|---|---|
| 2025 | 2025-12-31 | −79.49% | +16.22 pp |
| 2024 | 2024-12-31 | −95.71% | +35.39 pp |
| 2023 | 2023-12-31 | −131.11% | +47.50 pp |
| 2022 | 2022-12-31 | −178.60% | −69.97 pp |
| 2021 | 2021-12-31 | −108.63% | +13.17 pp |
| 2020 | 2020-12-31 | −121.80% | +287.18 pp |
| 2019 | 2019-12-31 | −408.98% | +312.20 pp |
| 2018 | 2018-12-31 | −721.18% | +11872.31 pp |
| 2017 | 2017-12-31 | −12,593.49% | +173877.94 pp |
| 2016 | 2016-12-31 | −186,471.43% | — |
Ultragenyx Pharmaceutical quarterly operating margin
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Q2.26
| Fiscal quarter | Period ended | Operating margin | Change (percentage points) |
|---|---|---|---|
| Q2 2026 | 2026-06-30 | −35.05% | +29.62 pp |
| Q1 2026 | 2026-03-31 | −124.26% | −21.39 pp |
| Q4 2025 | 2025-12-31 | −54.62% | +19.66 pp |
| Q3 2025 | 2025-09-30 | −106.85% | −12.23 pp |
| Q2 2025 | 2025-06-30 | −64.67% | +14.47 pp |
| Q1 2025 | 2025-03-31 | −102.88% | +49.05 pp |
| Q4 2024 | 2024-12-31 | −74.28% | +21.55 pp |
| Q3 2024 | 2024-09-30 | −94.62% | +53.36 pp |
| Q2 2024 | 2024-06-30 | −79.14% | +57.46 pp |
| Q1 2024 | 2024-03-31 | −151.93% | +1.42 pp |
| Q4 2023 | 2023-12-31 | −95.83% | +45.08 pp |
| Q3 2023 | 2023-09-30 | −147.98% | +100.16 pp |
| Q2 2023 | 2023-06-30 | −136.61% | +21.88 pp |
| Q1 2023 | 2023-03-31 | −153.34% | +17.58 pp |
| Q4 2022 | 2022-12-31 | −140.91% | −17.92 pp |
| Q3 2022 | 2022-09-30 | −248.14% | −138.12 pp |
| Q2 2022 | 2022-06-30 | −158.48% | −63.31 pp |
| Q1 2022 | 2022-03-31 | −170.93% | −63.71 pp |
| Q4 2021 | 2021-12-31 | −122.99% | −18.04 pp |
| Q3 2021 | 2021-09-30 | −110.02% | −48.26 pp |
| Q2 2021 | 2021-06-30 | −95.17% | +7.01 pp |
| Q1 2021 | 2021-03-31 | −107.22% | +225.11 pp |
| Q4 2020 | 2020-12-31 | −104.96% | +160.41 pp |
| Q3 2020 | 2020-09-30 | −61.76% | +395.73 pp |
| Q2 2020 | 2020-06-30 | −102.18% | +363.57 pp |
| Q1 2020 | 2020-03-31 | −332.33% | +213.64 pp |
| Q4 2019 | 2019-12-31 | −265.37% | +290.20 pp |
| Q3 2019 | 2019-09-30 | −457.49% | +304.61 pp |
| Q2 2019 | 2019-06-30 | −465.75% | +276.00 pp |
| Q1 2019 | 2019-03-31 | −545.97% | +357.72 pp |
| Q4 2018 | 2018-12-31 | −555.56% | +41723.73 pp |
| Q3 2018 | 2018-09-30 | −762.10% | — |
| Q2 2018 | 2018-06-30 | −741.75% | — |
| Q1 2018 | 2018-03-31 | −903.69% | — |
| Q3 2017 | 2017-09-30 | −42,279.29% | — |
Ultragenyx Pharmaceutical operating margin trends
Over the last five reported fiscal years, Ultragenyx Pharmaceutical's operating margin increased from −121.80% to −79.49%, a change of +42.31 percentage points. The latest reported quarter, Q2 2026, shows −35.05%.
About the metric
What operating margin means
Operating margin measures the percentage of revenue left after operating costs and expenses. It shows how much operating profit a company generates from each dollar of revenue.
Calculation and source
How operating margin is calculated
TickerStat calculates operating margin as SEC-reported operating income divided by SEC-reported revenue for the same fiscal period. Changes are shown in percentage points. Fiscal periods can differ from calendar years, so exact period-end dates are included.
Review Ultragenyx Pharmaceutical filings at SEC.gov ↗