Revenue
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $20.6M | $3.7M | $140.1M | $5.1M | $13.2M | $0 | $121,000 | $257,000 | $257,000 | $257,000 | $257,000 | $1.3M | $16.9M |
| Gross profit | — | $3.7M | $124.5M | $4.5M | $12.9M | — | — | — | — | — | — | $3.6M | $552,000 |
| Gross margin | — | 100.00% | 88.85% | 87.66% | 97.63% | — | — | — | — | — | — | 284.87% | 3.27% |
| Research & development | $22.3M | $26.4M | $30.9M | $27.3M | $23.8M | $36.5M | $38.4M | $21.6M | $18.3M | $20.1M | $16.4M | $8.3M | $4.4M |
| Operating expenses | $36.7M | $40.9M | $67.5M | $90.8M | $74.0M | $51.1M | $49.0M | $30.2M | $26.6M | $28.1M | $28.6M | $15.9M | $7.8M |
| Operating income | −$16.1M | −$37.1M | $72.7M | −$85.8M | −$60.8M | −$51.1M | −$48.9M | −$30.0M | −$26.3M | −$27.8M | −$28.3M | −$14.6M | −$7.2M |
| Operating margin | −78.03% | −990.84% | 51.85% | −1,684.48% | −462.19% | — | −40,430.58% | −11,666.54% | −10,241.25% | −10,823.74% | −11,030.74% | −1,166.16% | −42.74% |
| EBITDA | −$8.4M | −$37.1M | $73.2M | −$85.2M | −$60.5M | −$51.0M | −$48.8M | −$29.9M | −$26.3M | −$27.8M | −$27.9M | −$13.4M | −$5.9M |
| EBITDA margin | −40.95% | −990.84% | 52.27% | −1,672.58% | −459.31% | — | −40,338.84% | −11,645.91% | −10,225.29% | −10,813.62% | −10,856.81% | −1,067.60% | −34.85% |
| Net income | −$8.6M | −$21.3M | $67.0M | −$62.8M | −$32.9M | −$55.2M | −$53.7M | −$12.5M | −$25.1M | −$30.0M | −$32.6M | −$4.2M | −$30.5M |
| Net profit margin | −41.79% | −568.29% | 47.84% | −1,233.73% | −249.68% | — | −44,388.43% | −4,851.36% | −9,750.97% | −11,668.87% | −12,693.77% | −337.10% | −180.70% |
| Basic EPSper basic share | -$1.36 | -$3.52 | $11.20 | -$11.76 | -$10.00 | — | — | — | — | -$126.40 | -$214.40 | -$83.20 | -$11,157.60 |
| Diluted EPSper diluted share | -$1.36 | -$3.52 | $11.12 | -$11.76 | -$10.00 | — | — | — | — | -$126.40 | -$214.40 | -$215.20 | -$11,157.60 |
Reported shareholders
| Holder | % owned |
|---|---|
Angulo Gonzalez David | ≈13.64%1.36M shares |
GREAT POINT PARTNERS LLC | 9.49%944.29K shares |
Squadron Capital Management LLC | 7.61%756.88K shares |
Sukenick Scott | ≈5.77%574.54K shares |
ADAGE CAPITAL PARTNERS GP, L.L.C. | 5.46%543.48K shares |
Propel Bio Management, LLC | 5.46%543.48K shares |
Macleod ivor | ≈4.01%398.53K shares |
Woodline Partners LP | 3.89%387.52K shares |
VANGUARD CAPITAL MANAGEMENT LLC | 2.98%296.75K shares |
Avidity Partners Management LP | 2.62%260.21K shares |
KINGDON CAPITAL MANAGEMENT, L.L.C. | 2.49%247.81K shares |
MILLENNIUM MANAGEMENT LLC | 1.82%180.79K shares |
HEIGHTS CAPITAL MANAGEMENT, INC | 1.51%150.55K shares |
DAFNA Capital Management LLC | 1.37%135.87K shares |
Empery Asset Management, LP | 1.27%126.45K shares |
ACADIAN ASSET MANAGEMENT LLC | 1.17%116.67K shares |
GEODE CAPITAL MANAGEMENT, LLC | 0.83%82.09K shares |
RENAISSANCE TECHNOLOGIES LLC | 0.77%76.53K shares |
GILMAN STEVEN C | ≈0.70%70K shares |
VANGUARD FIDUCIARY TRUST CO | 0.58%57.97K shares |
Percentages use 9.95M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Apr 1, 2026Form 4 | Angulo Gonzalez DavidChief Executive Officer | BuyCommon Stock | 108.7K | — | — | 1.36M |
| Apr 1, 2026Form 4 | Angulo Gonzalez DavidChief Executive Officer | BuyWarrant to Purchase Common Stock · derivative | 108.7K | — | — | 108.7K |
| Sep 12, 2024Form 4 | Angulo Gonzalez DavidChief Executive Officer | BuyCommon Stock | 20.0K | $1.37 | $27.4K | 507.9K |