Revenue
2020
2021
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | |
|---|---|---|---|---|---|---|
| Revenue | $81,000 | $77,000 | $306,000 | $268,000 | $82,000 | $25,000 |
| Gross profit | −$83,000 | −$5,000 | $96,000 | $75,000 | — | — |
| Gross margin | −102.47% | −6.49% | 31.37% | 27.99% | — | — |
| Research & development | $13.2M | $14.7M | $15.2M | $14.2M | $11.0M | $7.8M |
| Operating expenses | $36.6M | $36.7M | $40.1M | $45.9M | $35.5M | $18.0M |
| Operating income | −$36.5M | −$36.6M | −$39.8M | −$45.7M | −$35.4M | −$18.0M |
| Operating margin | −45,066.67% | −47,577.92% | −13,013.40% | −17,034.33% | −43,164.63% | −71,884.00% |
| EBITDA | −$35.6M | −$35.8M | −$38.9M | −$44.9M | −$34.7M | −$17.1M |
| EBITDA margin | −43,906.17% | −46,496.10% | −12,719.28% | −16,752.24% | −42,360.98% | −68,304.00% |
| Net income | −$31.9M | −$32.9M | −$36.2M | −$44.2M | −$35.0M | −$19.8M |
| Net profit margin | −39,417.28% | −42,724.68% | −11,843.79% | −16,487.31% | −42,693.90% | −79,392.00% |
| Basic EPSper basic share | -$0.67 | -$0.99 | -$1.16 | -$1.43 | -$2.33 | -$12.76 |
| Diluted EPSper diluted share | -$0.67 | -$0.99 | -$1.16 | -$1.43 | -$2.33 | -$12.76 |
Reported shareholders
| Holder | % owned |
|---|---|
BAKER BROS. ADVISORS LP | 14.29%5.5M shares |
Whetstone Capital Advisors, LLC | 8.60%3.31M shares |
Aberdeen Group plc | 7.16%2.75M shares |
Vivo Capital, LLC | 4.29%1.65M shares |
VANGUARD CAPITAL MANAGEMENT LLC | 3.37%1.3M shares |
Lindgardt Zhenya | ≈2.25%865.01K shares |
CRITCHFIELD GREGORY C | ≈2.14%822.87K shares |
CAPTRUST FINANCIAL ADVISORS | 1.39%535.76K shares |
GEODE CAPITAL MANAGEMENT, LLC | 0.91%348.97K shares |
Aerts Austin | ≈0.78%301.19K shares |
BlackRock, Inc. | 0.58%221.37K shares |
AWM Investment Company, Inc. | 0.54%207.38K shares |
VANGUARD FIDUCIARY TRUST CO | 0.44%170.91K shares |
Kearney Paul | ≈0.43%163.96K shares |
Jackson Benjamin | ≈0.42%161.76K shares |
Boniface John J. | ≈0.38%145.84K shares |
STATE STREET CORP | 0.32%124.79K shares |
Inglis Tiffany Eul Davis | ≈0.24%92.08K shares |
Anderson Dyaarl Lee Jr. | ≈0.20%78K shares |
Harrison Robert Gardner | ≈0.20%76.71K shares |
Percentages use 38.47M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Jun 11, 2026Form 4 | Inglis Tiffany Eul DavisChief Medical Officer | SellClass A Common Stock | 362 | $2.01 | $727.62 | 92.1K |
| Jun 11, 2026Form 4 | Anderson Dyaarl Lee Jr.Chief Commercial Officer | SellClass A Common Stock | 4.7K | $2.01 | $9.5K | 78.0K |
| Jun 11, 2026Form 4 | Aerts AustinChief Financial Officer | SellClass A Common Stock | 2.0K | $2.01 | $4.1K | 301.2K |
| Jun 11, 2026Form 4 | Lindgardt ZhenyaChief Executive Officer | SellClass A Common Stock | 7.0K | $2.01 | $14.0K | 865.0K |
| Jun 11, 2026Form 4 | Jackson BenjaminGeneral Counsel | SellClass A Common Stock | 2.2K | $2.01 | $4.4K | 161.8K |