Revenue
2022
2023
2024
2025
Spruce Biosciences, Inc. (SPRB)
Price$53.05Cached quote
Net income
2019
2020
2021
2022
2023
2024
2025
Free cash flow
2019
2020
2021
2022
2023
2024
Total cash / debt
CashTotal debt
2019
2020
2021
2022
2023
2024
2025
Financial statements
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | |
|---|---|---|---|---|---|---|---|
| Revenue | $0 | $4.9M | $10.1M | $0 | — | — | — |
| Research & development | $19.5M | $46.4M | $49.4M | $35.2M | $30.7M | $23.9M | $10.8M |
| Operating expenses | $36.5M | $61.1M | $62.1M | $47.3M | $42.1M | $29.4M | $13.1M |
| Operating income | −$36.5M | −$56.2M | −$52.0M | −$47.3M | −$42.1M | −$29.4M | −$13.1M |
| Operating margin | — | −1,143.37% | −515.34% | — | — | — | — |
| EBITDA | −$36.5M | −$56.1M | −$51.9M | −$47.2M | −$42.0M | −$29.4M | −$13.1M |
| EBITDA margin | — | −1,142.44% | −514.65% | — | — | — | — |
| Net income | −$39.0M | −$53.0M | −$47.9M | −$46.2M | −$42.3M | −$29.5M | −$13.1M |
| Net profit margin | — | −1,079.94% | −474.96% | — | — | — | — |
| Basic EPSper basic share | -$50.83 | -$96.40 | -$93.00 | -$147.00 | -$135.75 | -$369.75 | -$1,284.00 |
| Diluted EPSper diluted share | -$50.83 | -$96.40 | -$93.00 | -$147.00 | -$135.75 | -$369.75 | -$1,284.00 |
Owners
Reported shareholders
9.08%of listed shares
AIGH Capital Management LLC250K shares · Jun 30, 2026
View holders
| Holder | % owned |
|---|---|
AIGH Capital Management LLC | 9.08%250K shares |
ORBIMED ADVISORS LLC | 7.27%200K shares |
BlackRock, Inc. | 6.82%187.84K shares |
Charlton Ralph William III | ≈5.86%161.34K shares |
MILLENNIUM MANAGEMENT LLC | 5.85%160.98K shares |
Ikarian Capital, LLC | 4.41%121.36K shares |
VANGUARD CAPITAL MANAGEMENT LLC | 4.33%119.33K shares |
Alyeska Investment Group, L.P. | 2.97%81.67K shares |
GEODE CAPITAL MANAGEMENT, LLC | 2.56%70.55K shares |
ADAR1 Capital Management, LLC | 2.46%67.72K shares |
Cable Car Capital, LP | 2.18%60K shares |
CITADEL ADVISORS LLC | 1.89%51.91K shares |
STATE STREET CORP | 1.83%50.45K shares |
BOOTHBAY FUND MANAGEMENT, LLC | 1.53%42.08K shares |
STEMPOINT CAPITAL LP | 1.50%41.39K shares |
Eversept Partners, LP | 1.45%40K shares |
Carlyle Group Inc. | 1.40%38.62K shares |
GOLDMAN SACHS GROUP INC | 1.18%32.35K shares |
Affinity Asset Advisors, LLC | 1.09%30K shares |
DIADEMA PARTNERS LP | 1.09%30K shares |
Percentages use 2.75M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
Source: SEC Form 13F ↗Updated Sep 29, 2026 · Quarterly data
Insider buys & sells
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Oct 6, 2025Form 4 | Parkman Healthcare Partners LLC +1TenPercentOwner | SellCommon Stock, $0.001 par value per share · indirect | 25 | $17.46 | $436.50 | 1.1K |
| Oct 6, 2025Form 4 | Parkman Healthcare Partners LLC +1TenPercentOwner | SellCommon Stock, $0.001 par value per share · indirect | 232 | $19.33 | $4.5K | 1.1K |
| Oct 6, 2025Form 4 | Parkman Healthcare Partners LLC +1TenPercentOwner | BuyCommon Stock, $0.001 par value per share · indirect | 256 | $17.91 | $4.6K | 1.3K |
| Oct 6, 2025Form 4 | Parkman Healthcare Partners LLCTenPercentOwner | SellCommon Stock, $0.001 par value per share · indirect | 25 | $17.46 | $436.50 | 1.1K |
| Oct 6, 2025Form 4 | Parkman Healthcare Partners LLCTenPercentOwner | SellCommon Stock, $0.001 par value per share · indirect | 232 | $19.33 | $4.5K | 1.1K |