Spero Therapeutics annual net profit margin
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
Spero Therapeutics Net Profit Margin Growth & History (SPRO)
Spero Therapeutics's net profit margin was 68.11% for fiscal 2025.
View full Spero Therapeutics company overviewSpero Therapeutics annual net profit margin history
| Fiscal year | Period ended | Net profit margin | Change (percentage points) |
|---|---|---|---|
| 2025 | 2025-12-31 | 68.11% | +18549.51 pp |
| 2024 | 2024-12-31 | −18,481.40% | −20925.77 pp |
| 2023 | 2023-12-31 | 2,444.37% | +4298.75 pp |
| 2022 | 2022-12-31 | −1,854.37% | +1070.71 pp |
| 2021 | 2021-12-31 | −2,925.08% | +27423.76 pp |
| 2020 | 2020-12-31 | −30,348.84% | −29064.57 pp |
| 2019 | 2019-12-31 | −1,284.27% | −232.83 pp |
| 2018 | 2018-12-31 | −1,051.44% | +906.27 pp |
| 2017 | 2017-12-31 | −1,957.71% | +5651.55 pp |
| 2016 | 2016-12-31 | −7,609.25% | — |
Spero Therapeutics quarterly net profit margin
Q1.17
Q2.17
Q3.17
Q4.17
Q1.18
Q2.18
Q3.18
Q4.18
Q1.19
Q2.19
Q3.19
Q4.19
Q1.20
Q2.20
Q3.20
Q1.21
Q2.21
Q3.21
Q1.22
Q2.22
Q3.22
Q4.22
Q1.23
Q2.23
Q3.23
Q4.23
Q1.24
Q2.24
Q3.24
Q4.24
Q1.25
Q4.25
| Fiscal quarter | Period ended | Net profit margin | Change (percentage points) |
|---|---|---|---|
| Q4 2025 | 2025-12-31 | 250.68% | +40419.91 pp |
| Q1 2025 | 2025-03-31 | −115,550.00% | −106500.71 pp |
| Q4 2024 | 2024-12-31 | −40,169.23% | −63131.56 pp |
| Q3 2024 | 2024-09-30 | −26,380.00% | −24912.11 pp |
| Q2 2024 | 2024-06-30 | −15,668.42% | −11244.63 pp |
| Q1 2024 | 2024-03-31 | −9,049.29% | −3085.16 pp |
| Q4 2023 | 2023-12-31 | 22,962.33% | +13327.44 pp |
| Q3 2023 | 2023-09-30 | −1,467.89% | −386.56 pp |
| Q2 2023 | 2023-06-30 | −4,423.79% | −1220.67 pp |
| Q1 2023 | 2023-03-31 | −5,964.13% | +7315.23 pp |
| Q4 2022 | 2022-12-31 | 9,634.89% | — |
| Q3 2022 | 2022-09-30 | −1,081.33% | +2096.64 pp |
| Q2 2022 | 2022-06-30 | −3,203.13% | −2319.93 pp |
| Q1 2022 | 2022-03-31 | −13,279.35% | −13013.60 pp |
| Q3 2021 | 2021-09-30 | −3,177.97% | +46558.88 pp |
| Q2 2021 | 2021-06-30 | −883.19% | +33430.53 pp |
| Q1 2021 | 2021-03-31 | −265.75% | +13521.23 pp |
| Q3 2020 | 2020-09-30 | −49,736.84% | −39446.14 pp |
| Q2 2020 | 2020-06-30 | −34,313.73% | −14612.23 pp |
| Q1 2020 | 2020-03-31 | −13,786.98% | −13653.02 pp |
| Q4 2019 | 2019-12-31 | −3,589.94% | −2963.52 pp |
| Q3 2019 | 2019-09-30 | −10,290.70% | −8700.58 pp |
| Q2 2019 | 2019-06-30 | −19,701.49% | −17551.17 pp |
| Q1 2019 | 2019-03-31 | −133.96% | +789.19 pp |
| Q4 2018 | 2018-12-31 | −626.42% | +769.55 pp |
| Q3 2018 | 2018-09-30 | −1,590.12% | +57.45 pp |
| Q2 2018 | 2018-06-30 | −2,150.32% | +1532.01 pp |
| Q1 2018 | 2018-03-31 | −923.16% | +3273.99 pp |
| Q4 2017 | 2017-12-31 | −1,395.97% | — |
| Q3 2017 | 2017-09-30 | −1,647.57% | — |
| Q2 2017 | 2017-06-30 | −3,682.33% | — |
| Q1 2017 | 2017-03-31 | −4,197.14% | — |
Spero Therapeutics net profit margin trends
Over the last five fiscal years, Spero Therapeutics's net profit margin increased from −30,348.84% to 68.11%, a change of +30416.94 percentage points. The latest reported quarter, Q4 2025, shows 250.68%.
About the metric
What net profit margin means
Net profit margin measures the percentage of revenue remaining as net income after operating costs, interest, taxes, and other expenses. It shows how much bottom-line profit or loss a company generates from each dollar of revenue.
Calculation and source
How net profit margin is calculated
TickerStat calculates net profit margin as SEC-reported net income divided by SEC-reported revenue for the same fiscal period. Changes are shown in percentage points. Fiscal periods can differ from calendar years, so exact period-end dates are included.
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