Revenue
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $40.4M | $80.0M | $250.0M | $40.9M | $37.4M | $171.1M | $104.4M | $7.6M | $10.1M | $14.2M | $17.3M | — |
| Research & development | $134.7M | $127.4M | $92.2M | $60.8M | $73.8M | $108.8M | $119.7M | $64.9M | $62.3M | $42.2M | $27.7M | $8.9M |
| Operating expenses | $172.2M | $163.3M | $128.0M | $91.7M | $111.0M | $143.7M | $156.1M | $98.7M | $82.0M | $55.5M | $37.6M | $14.4M |
| Operating income | −$131.8M | −$83.3M | $122.0M | −$50.8M | −$73.6M | $27.4M | −$51.7M | −$91.1M | −$71.9M | −$41.3M | −$20.3M | −$14.4M |
| Operating margin | −326.56% | −104.11% | 48.80% | −124.27% | −196.76% | 16.00% | −49.51% | −1,195.63% | −709.06% | −290.43% | −116.85% | — |
| EBITDA | −$127.8M | −$78.6M | $126.5M | −$44.6M | −$68.5M | $31.2M | −$48.9M | −$89.0M | −$70.3M | −$40.7M | −$19.7M | −$14.2M |
| EBITDA margin | −316.50% | −98.19% | 50.58% | −109.14% | −182.96% | 18.23% | −46.86% | −1,167.84% | −693.32% | −286.13% | −113.38% | — |
| Net income | −$119.7M | −$65.0M | $132.3M | −$46.4M | −$71.2M | $36.7M | −$43.6M | −$88.3M | −$70.7M | −$40.2M | −$29.7M | −$16.3M |
| Net profit margin | −296.53% | −81.25% | 52.93% | −113.45% | −190.29% | 21.47% | −41.76% | −1,158.79% | −697.56% | −282.65% | −171.18% | — |
| Basic EPSper basic share | -$2.04 | -$1.13 | $3.08 | -$1.21 | -$1.89 | $0.99 | -$1.21 | -$2.75 | -$2.64 | -$1.59 | $9.14 | $27.83 |
| Diluted EPSper diluted share | -$2.04 | -$1.13 | $2.97 | -$1.21 | -$1.89 | $0.98 | -$1.21 | -$2.75 | -$2.64 | -$1.59 | $9.14 | $27.83 |
Reported shareholders
| Holder | % owned |
|---|---|
BlackRock, Inc. | 8.44%5.17M shares |
MILLENNIUM MANAGEMENT LLC | 7.25%4.44M shares |
ARMISTICE CAPITAL, LLC | 5.61%3.44M shares |
Vestal Point Capital, LP | 4.28%2.63M shares |
VANGUARD CAPITAL MANAGEMENT LLC | 3.83%2.35M shares |
GEODE CAPITAL MANAGEMENT, LLC | 2.17%1.33M shares |
Opaleye Management Inc. | 1.93%1.19M shares |
STATE STREET CORP | 1.76%1.08M shares |
TWO SIGMA INVESTMENTS, LP | 1.55%948.52K shares |
DIMENSIONAL FUND ADVISORS LP | 1.37%838.18K shares |
VANGUARD PORTFOLIO MANAGEMENT LLC | 1.32%810.09K shares |
CITADEL ADVISORS LLC | 1.28%784.07K shares |
MORGAN STANLEY | 1.14%697.33K shares |
Erste Asset Management GmbH | 1.04%638.9K shares |
RENAISSANCE TECHNOLOGIES LLC | 0.81%495.24K shares |
Sandrock Alfred | ≈0.77%472.55K shares |
ACADIAN ASSET MANAGEMENT LLC | 0.70%428.67K shares |
SPHERA FUNDS MANAGEMENT LTD. | 0.70%427.55K shares |
DIADEMA PARTNERS LP | 0.68%413.64K shares |
NORTHERN TRUST CORP | 0.67%411.8K shares |
Percentages use 61.27M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Apr 2, 2026Form 4 · 10b5-1 | Sandrock AlfredPresident and CEO | SellCommon Stock | 11.5K | $3.87 | $44.5K | 472.5K |
| Feb 24, 2026Form 4 · 10b5-1 | Swartz RobinCOO & CBO | SellCommon Stock | 6.5K | $3.77 | $24.3K | 199.7K |
| Feb 24, 2026Form 4 · 10b5-1 | Sandrock AlfredPresident and CEO | SellCommon Stock | 14.2K | $3.79 | $53.8K | 484.1K |
| Feb 24, 2026Form 4 · 10b5-1 | Jorgensen Nathan D.Chief Financial Officer | SellCommon Stock | 4.7K | $3.77 | $17.6K | 151.4K |
| Feb 24, 2026Form 4 · 10b5-1 | Carter Todd AlfredChief Scientific Officer | SellCommon Stock | 4.2K | $3.76 | $15.7K | 145.7K |