Revenue
2018
2019
2020
2021
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $7.1M | $26.0M | $24.4M | $15.2M | $14.0M | $14.0M | $0 | $20.2M | — | — | — | — | — | — | — | — | — | — |
| Gross profit | $6.4M | $23.0M | $21.5M | $13.9M | $14.0M | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Gross margin | 89.36% | 88.36% | 88.47% | 91.23% | 100.00% | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Research & development | $91.0M | $51.0M | $48.9M | $32.7M | $19.7M | $15.0M | $12.8M | $17.9M | $12.1M | $11.4M | — | — | — | — | — | — | — | — |
| Operating expenses | $121.5M | $93.4M | $96.3M | $77.9M | $112.3M | $17.1M | $24.4M | $31.3M | $21.4M | $16.6M | — | — | — | — | — | — | — | — |
| Operating income | −$114.4M | −$67.5M | −$71.9M | −$62.7M | −$111.2M | −$2.5M | −$24.4M | −$11.2M | −$21.4M | −$16.6M | −$23,006 | −$23,972 | −$22,824 | −$22,391 | −$23,585 | −$20,509 | — | — |
| Operating margin | −1,601.12% | −259.62% | −295.36% | −411.94% | −794.41% | −18.21% | — | −55.47% | — | — | — | — | — | — | — | — | — | — |
| EBITDA | −$114.3M | −$67.3M | −$71.8M | −$62.5M | −$111.1M | −$2.5M | −$24.4M | −$11.1M | −$21.3M | −$16.6M | — | — | — | — | — | — | — | — |
| EBITDA margin | −1,600.01% | −258.88% | −294.67% | −410.90% | −793.66% | −18.14% | — | −55.24% | — | — | — | — | — | — | — | — | — | — |
| Net income | −$20.6M | −$63.7M | −$65.8M | −$60.5M | −$110.1M | −$3.5M | −$23.3M | −$10.4M | −$21.4M | −$17.0M | −$31,440 | −$30,799 | −$28,701 | −$27,365 | −$27,185 | −$22,395 | −$19,996 | −$33,623 |
| Net profit margin | −288.26% | −245.13% | −270.04% | −397.69% | −786.36% | −24.84% | — | −51.58% | — | — | — | — | — | — | — | — | — | — |
| Basic EPSper basic share | -$0.33 | -$2.36 | -$2.44 | -$2.69 | -$12.41 | -$1.76 | -$8.55 | -$4.65 | -$15.44 | -$367.62 | -$0.15 | -$0.15 | -$0.15 | -$0.15 | -$0.15 | $0.00 | — | — |
| Diluted EPSper diluted share | -$0.33 | -$2.36 | -$2.44 | -$2.69 | -$12.41 | -$1.76 | -$8.55 | -$4.65 | -$15.44 | -$367.62 | -$0.15 | -$0.15 | -$0.15 | -$0.15 | -$0.15 | $0.00 | — | — |
Reported shareholders
| Holder | % owned |
|---|---|
Yu Fan | 8.53%4.86M shares |
ACUTA CAPITAL PARTNERS, LLC | 8.22%4.69M shares |
QVT Financial LP | 8.10%4.62M shares |
MONTANOVA CAPITAL, LLC | 7.54%4.3M shares |
ORBIMED ADVISORS LLC | 6.90%3.93M shares |
Dalal Anupam | ≈5.98%3.41M shares |
Avoro Capital Advisors LLC | 5.00%2.85M shares |
Castelein Caley | ≈4.28%2.44M shares |
Siren, L.L.C. | 4.10%2.34M shares |
KVP Capital Advisors, LP | 3.80%2.17M shares |
BlackRock, Inc. | 3.37%1.92M shares |
Desai Neil | ≈3.18%1.81M shares |
VANGUARD CAPITAL MANAGEMENT LLC | 2.44%1.39M shares |
ADAR1 Capital Management, LLC | 2.35%1.34M shares |
Zhao Baiteng | ≈2.19%1.25M shares |
ACORN CAPITAL ADVISORS, LLC | 2.00%1.14M shares |
STEMPOINT CAPITAL LP | 1.79%1.02M shares |
GEODE CAPITAL MANAGEMENT, LLC | 1.58%899.78K shares |
Ally Bridge Group (NY) LLC | 1.43%817.94K shares |
Lennon David James | ≈1.00%569.64K shares |
Percentages use 57.01M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Apr 16, 2026Form 4 | Giacobello Scott M.CHIEF FINANCIAL OFFICER | SellCommon Stock | 141.6K | $4.13 | $584.8K | 295.2K |
| Apr 15, 2026Form 4 | Giacobello Scott M.CHIEF FINANCIAL OFFICER | SellCommon Stock | 77.0K | $3.86 | $297.2K | 436.8K |
| Apr 14, 2026Form 4 | BALL BRYANSee remarks | SellCommon Stock | 92.5K | $3.64 | $336.6K | 397.1K |
| Apr 13, 2026Form 4 | BALL BRYANSee remarks | SellCommon Stock | 26.4K | $3.46 | $91.3K | 489.6K |
| Apr 10, 2026Form 4 | BALL BRYANSee remarks | SellCommon Stock | 6.6K | $3.43 | $22.6K | 516.0K |