Zymeworks Operating Margin Growth & History (ZYME)

Zymeworks's operating margin was −87.34% for fiscal 2025.

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Zymeworks annual operating margin history

Zymeworks annual operating margin

Fiscal yearPeriod endedOperating marginChange (percentage points)
20252025-12-31−87.34%+92.35 pp
20242024-12-31−179.69%+1.93 pp
20232023-12-31−181.62%−213.26 pp
20222022-12-3131.64%+839.86 pp
20212021-12-31−808.22%−326.93 pp
20202020-12-31−481.29%

Zymeworks operating margin trends

Over the last five reported fiscal years, Zymeworks's operating margin increased from −481.29% to −87.34%, a change of +393.95 percentage points. The latest reported quarter, Q2 2026, shows −918.95%.

About the metric

What operating margin means

Operating margin measures the percentage of revenue left after operating costs and expenses. It shows how much operating profit a company generates from each dollar of revenue.

Calculation and source

How operating margin is calculated

TickerStat calculates operating margin as SEC-reported operating income divided by SEC-reported revenue for the same fiscal period. Changes are shown in percentage points. Fiscal periods can differ from calendar years, so exact period-end dates are included.

Review Zymeworks filings at SEC.gov ↗