Revenue
2010
2011
2012
2013
2014
2015
2016
2017
2018
2020
2021
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $5.8M | $0 | $3.5M | $1.4M | $3.0M | $10.0M | — | $3.0M | $837,000 | $889,000 | $1.0M | $925,000 | $2.0M | $4.4M | $1.8M | $481,000 |
| Gross profit | $4.3M | $0 | $1.9M | $964,000 | — | — | — | — | — | — | — | $925,000 | $1.9M | $4.1M | $1.7M | $341,000 |
| Gross margin | 73.68% | — | 54.14% | 68.18% | — | — | — | — | — | — | — | 100.00% | 93.88% | 93.94% | 91.95% | 70.89% |
| Research & development | $26.8M | $34.4M | $31.1M | $29.0M | $38.7M | $30.1M | $48.6M | $38.7M | $17.0M | $10.7M | $4.7M | $333,000 | $884,000 | $2.0M | $3.6M | $3.3M |
| Operating expenses | $95.3M | $64.2M | $50.6M | $52.3M | $92.8M | $91.4M | $77.1M | $61.2M | $28.7M | $24.8M | $19.6M | $4.1M | $5.8M | $8.7M | $9.7M | $8.2M |
| Operating income | −$89.4M | −$64.2M | −$47.1M | −$50.9M | −$89.8M | −$81.4M | −$77.1M | −$58.2M | −$27.8M | −$23.9M | −$18.5M | −$3.1M | −$3.8M | −$4.3M | −$7.9M | −$7.8M |
| Operating margin | −1,536.91% | — | −1,346.71% | −3,600.78% | −2,994.53% | −814.20% | — | −1,940.16% | −3,325.69% | −2,686.28% | −1,783.27% | −338.49% | −186.29% | −98.00% | −428.28% | −1,612.68% |
| EBITDA | −$86.9M | −$62.2M | −$44.8M | −$47.8M | −$86.6M | −$76.8M | −$69.3M | −$55.8M | −$27.1M | −$23.1M | −$18.0M | −$3.1M | −$3.8M | −$3.9M | −$7.6M | −$7.5M |
| EBITDA margin | −1,493.11% | — | −1,281.34% | −3,382.04% | −2,886.20% | −768.34% | — | −1,861.44% | −3,237.16% | −2,593.48% | −1,730.29% | −337.30% | −186.14% | −88.49% | −415.61% | −1,563.20% |
| Net income | $71.2M | −$63.7M | −$54.2M | −$39.7M | −$84.9M | −$84.2M | −$76.3M | −$56.7M | −$27.3M | −$21.9M | −$14.5M | −$26.8M | $4.4M | −$10.5M | −$2.5M | −$7.5M |
| Net profit margin | 1,223.08% | — | −1,548.23% | −2,807.36% | −2,831.20% | −842.34% | — | −1,890.29% | −3,263.92% | −2,460.40% | −1,396.73% | −2,894.92% | 217.87% | −239.15% | −137.68% | −1,566.94% |
| Basic EPSper basic share | $1.34 | -$1.55 | -$2.53 | -$5.53 | -$21.57 | -$22.75 | -$37.75 | -$29.75 | -$16.50 | -$16.00 | -$13.25 | -$381.50 | $76.75 | -$13.00 | -$5.50 | -$15.00 |
| Diluted EPSper diluted share | $1.01 | -$1.55 | -$2.53 | -$5.53 | -$21.50 | -$22.75 | -$37.75 | -$29.75 | -$16.50 | -$16.00 | -$13.25 | -$381.50 | $76.00 | -$13.00 | -$5.50 | -$15.00 |
Reported shareholders
| Holder | % owned |
|---|---|
Nantahala Capital Management, LLC | 17.95%10.27M shares |
BlackRock, Inc. | 5.86%3.35M shares |
Cable Car Capital, LP | 5.26%3.01M shares |
AIGH Capital Management LLC | 5.22%2.99M shares |
VANGUARD CAPITAL MANAGEMENT LLC | 3.86%2.21M shares |
OneDigital Investment Advisors LLC | 2.89%1.65M shares |
AWM Investment Company, Inc. | 2.60%1.49M shares |
Seshadri Vishwas | ≈2.40%1.37M shares |
GEODE CAPITAL MANAGEMENT, LLC | 2.20%1.26M shares |
KENNEDY CAPITAL MANAGEMENT LLC | 2.17%1.24M shares |
GOLDMAN SACHS GROUP INC | 2.14%1.22M shares |
STATE STREET CORP | 1.82%1.04M shares |
Propel Bio Management, LLC | 1.72%983.07K shares |
NAN FUNG TRINITY (HK) LTD | 1.67%956.77K shares |
Diametric Capital, LP | 1.32%755.02K shares |
J. Goldman & Co LP | 1.19%678.17K shares |
SILVERARC CAPITAL MANAGEMENT, LLC | 1.07%610.41K shares |
Rubric Capital Management LP | 1.06%608.77K shares |
Stonepine Capital Management, LLC | 0.97%557.28K shares |
NORTHERN TRUST CORP | 0.97%552.63K shares |
Percentages use 57.23M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Jun 15, 2026Form 4 | Silverstein Christine BerniDirector | SellCommon Stock | 18.2K | $5.71 | $103.7K | 119.6K |
| Jun 9, 2026Form 4 · 10b5-1 | Vazzano Joseph WalterChief Financial Officer | SellCommon Stock | 25.6K | $5.39 | $138.2K | 518.4K |
| Jun 9, 2026Form 4 · 10b5-1 | Vazzano Joseph WalterChief Financial Officer | SellCommon Stock | 13.4K | $5.30 | $71.1K | 544.1K |
| Jun 9, 2026Form 4 | Vasanthavada MadhavChief Commercial Officer | SellCommon Stock | 5.5K | $5.30 | $28.9K | 303.5K |
| Jun 9, 2026Form 4 | Seshadri VishwasChief Executive Officer | SellCommon Stock | 31.9K | $5.30 | $169.2K | 1.37M |