Revenue
2018
2019
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | — | — | $0 | $0 | — | — | — | — | — | — | — | — | — |
| Research & development | $23.0M | $22.8M | $15.8M | $30.1M | $24.0M | $6.9M | $9.7M | $5.9M | $3.1M | $286,000 | $25.1M | $46.2M | $55.3M | $39.9M | $21.6M | $18.5M | $20.2M |
| Operating expenses | $54.9M | $39.1M | $27.3M | $40.8M | — | — | $16.5M | $12.8M | — | — | $36.9M | $56.6M | $65.2M | — | — | — | — |
| Operating income | −$54.9M | −$39.1M | −$27.3M | −$40.8M | — | — | −$16.5M | −$12.8M | — | — | — | — | — | — | — | — | — |
| EBITDA | −$53.6M | −$37.4M | −$26.7M | −$40.3M | — | — | −$16.3M | −$12.6M | — | — | — | — | — | — | — | — | — |
| Net income | −$54.6M | −$39.8M | −$29.8M | −$42.4M | −$33.2M | −$14.7M | −$16.4M | −$12.7M | −$10.6M | −$1.2M | −$828,000 | −$26.2M | −$31.8M | −$21.1M | −$14.7M | −$12.6M | −$5.5M |
| Basic EPSper basic share | -$1.25 | -$1.24 | -$1.50 | -$4.00 | -$4.08 | -$5.42 | -$39.76 | -$72.29 | -$441.40 | -$11.63 | -$128.00 | -$290.00 | -$434.00 | -$312.00 | -$302.00 | -$358.00 | -$190.00 |
| Diluted EPSper diluted share | -$1.25 | -$1.24 | -$1.50 | -$4.00 | -$4.08 | -$5.42 | -$39.76 | -$72.29 | -$441.40 | -$11.63 | -$128.00 | -$290.00 | -$434.00 | -$312.00 | -$302.00 | -$358.00 | -$190.00 |
Reported shareholders
| Holder | % owned |
|---|---|
Frazier Life Sciences Management, L.P. | 7.41%7.61M shares |
TPG GP A, LLC | 6.70%6.88M shares |
venBio Partners LLC | 5.76%5.91M shares |
Logos Global Management LP | 5.28%5.43M shares |
BlackRock, Inc. | 5.13%5.27M shares |
FRANKLIN RESOURCES INC | 4.82%4.95M shares |
Paradigm Biocapital Advisors LP | 4.82%4.95M shares |
VANGUARD CAPITAL MANAGEMENT LLC | 4.03%4.14M shares |
Propel Bio Management, LLC | 3.93%4.03M shares |
MARSHALL WACE, LLP | 3.67%3.77M shares |
STATE STREET CORP | 2.87%2.95M shares |
Venrock Adviser, LLC | 2.68%2.75M shares |
Vivo Capital, LLC | 2.68%2.75M shares |
Jupiter Topco LLC | 2.68%2.75M shares |
EVENTIDE ASSET MANAGEMENT, LLC | 2.16%2.22M shares |
GEODE CAPITAL MANAGEMENT, LLC | 2.01%2.06M shares |
Alyeska Investment Group, L.P. | 1.87%1.93M shares |
Simplify Asset Management Inc. | 1.39%1.43M shares |
WELLINGTON MANAGEMENT GROUP LLP | 1.39%1.43M shares |
LPL Financial LLC | 0.88%902.26K shares |
Percentages use 102.72M shares of this listed class outstanding on Jun 30, 2026.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Sep 18, 2025Form 4 | Oki Mark KChief Financial Officer | SellCommon Stock | 50.1K | $2.92 | $146.2K | 127.9K |
| Sep 18, 2025Form 4 | Stewart Richard AlistairChief Executive Officer | SellCommon Stock | 129.5K | $2.92 | $378.1K | 228.9K |
| Sep 4, 2025Form 4 | Wan JerryPrincipal Accounting Officer | SellCommon Stock | 14.1K | $2.77 | $39.0K | 32.7K |
| Sep 4, 2025Form 4 | KING THOMAS BRAXTONDirector | SellCommon Stock | 139.9K | $2.77 | $387.4K | 315.1K |
| Sep 4, 2025Form 4 | JACOBS CINDYPresident & CMO | SellCommon Stock | 27.6K | $2.77 | $76.5K | 115.6K |