Alnylam Pharmaceuticals annual return on equity
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2025
Alnylam Pharmaceuticals Return on Equity (ROE) Growth & History (ALNY)
Alnylam Pharmaceuticals's return on equity was 73.28% for fiscal 2025.
View full Alnylam Pharmaceuticals company overviewAlnylam Pharmaceuticals annual return on equity history
| Fiscal year | Period ended | Return on equity | Change (percentage points) |
|---|---|---|---|
| 2025 | 2025-12-31 | 73.28% | — |
| 2022 | 2022-12-31 | −526.14% | −419.84 pp |
| 2021 | 2021-12-31 | −106.31% | −36.38 pp |
| 2020 | 2020-12-31 | −69.92% | −5.26 pp |
| 2019 | 2019-12-31 | −64.66% | −15.03 pp |
| 2018 | 2018-12-31 | −49.63% | −13.09 pp |
| 2017 | 2017-12-31 | −36.54% | +1.00 pp |
| 2016 | 2016-12-31 | −37.54% | −11.18 pp |
| 2015 | 2015-12-31 | −26.36% | +33.38 pp |
| 2014 | 2014-12-31 | −59.74% | −15.61 pp |
| 2013 | 2013-12-31 | −44.13% | +39.99 pp |
| 2012 | 2012-12-31 | −84.12% | −42.38 pp |
| 2011 | 2011-12-31 | −41.74% | −15.85 pp |
| 2010 | 2010-12-31 | −25.89% | −0.85 pp |
| 2009 | 2009-12-31 | −25.04% | — |
Alnylam Pharmaceuticals quarterly return on equity
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Q2.26
| Fiscal quarter | Period ended | Return on equity | Change (percentage points) |
|---|---|---|---|
| Q2 2026 | 2026-06-30 | 13.54% | +28.26 pp |
| Q1 2026 | 2026-03-31 | 22.10% | +29.50 pp |
| Q4 2025 | 2025-12-31 | 29.94% | +198.40 pp |
| Q3 2025 | 2025-09-30 | 63.63% | +825.53 pp |
| Q2 2025 | 2025-06-30 | −14.72% | — |
| Q1 2025 | 2025-03-31 | −7.40% | — |
| Q4 2024 | 2024-12-31 | −168.47% | — |
| Q3 2024 | 2024-09-30 | −761.91% | — |
| Q3 2022 | 2022-09-30 | −748.92% | −723.50 pp |
| Q2 2022 | 2022-06-30 | −96.12% | −74.81 pp |
| Q1 2022 | 2022-03-31 | −48.58% | −27.96 pp |
| Q4 2021 | 2021-12-31 | −38.46% | −16.63 pp |
| Q3 2021 | 2021-09-30 | −25.42% | −6.04 pp |
| Q2 2021 | 2021-06-30 | −21.30% | −8.27 pp |
| Q1 2021 | 2021-03-31 | −20.62% | −7.55 pp |
| Q4 2020 | 2020-12-31 | −21.83% | −3.69 pp |
| Q3 2020 | 2020-09-30 | −19.37% | −6.98 pp |
| Q2 2020 | 2020-06-30 | −13.04% | +0.25 pp |
| Q1 2020 | 2020-03-31 | −13.07% | −0.30 pp |
| Q4 2019 | 2019-12-31 | −18.14% | −2.92 pp |
| Q3 2019 | 2019-09-30 | −12.40% | +3.43 pp |
| Q2 2019 | 2019-06-30 | −13.29% | −3.59 pp |
| Q1 2019 | 2019-03-31 | −12.77% | −4.75 pp |
| Q4 2018 | 2018-12-31 | −15.21% | −5.14 pp |
| Q3 2018 | 2018-09-30 | −15.83% | −4.56 pp |
| Q2 2018 | 2018-06-30 | −9.69% | +2.43 pp |
| Q1 2018 | 2018-03-31 | −8.02% | +4.23 pp |
| Q4 2017 | 2017-12-31 | −10.07% | +1.60 pp |
| Q3 2017 | 2017-09-30 | −11.27% | −1.42 pp |
| Q2 2017 | 2017-06-30 | −12.12% | −4.24 pp |
| Q1 2017 | 2017-03-31 | −12.25% | −3.86 pp |
| Q4 2016 | 2016-12-31 | −11.67% | −4.66 pp |
| Q3 2016 | 2016-09-30 | −9.85% | −4.22 pp |
| Q2 2016 | 2016-06-30 | −7.88% | −2.94 pp |
| Q1 2016 | 2016-03-31 | −8.39% | −4.22 pp |
| Q4 2015 | 2015-12-31 | −7.02% | −4.69 pp |
| Q3 2015 | 2015-09-30 | −5.63% | −0.86 pp |
| Q2 2015 | 2015-06-30 | −4.94% | −0.30 pp |
| Q1 2015 | 2015-03-31 | −4.17% | +36.79 pp |
| Q4 2014 | 2014-12-31 | −2.32% | +9.07 pp |
| Q3 2014 | 2014-09-30 | −4.76% | +5.04 pp |
| Q2 2014 | 2014-06-30 | −4.65% | +1.22 pp |
| Q1 2014 | 2014-03-31 | −40.96% | −36.91 pp |
| Q4 2013 | 2013-12-31 | −11.39% | +28.57 pp |
| Q3 2013 | 2013-09-30 | −9.80% | +0.87 pp |
| Q2 2013 | 2013-06-30 | −5.86% | +0.86 pp |
| Q1 2013 | 2013-03-31 | −4.05% | +3.16 pp |
| Q4 2012 | 2012-12-31 | −39.96% | −28.33 pp |
| Q3 2012 | 2012-09-30 | −10.67% | −0.66 pp |
| Q2 2012 | 2012-06-30 | −6.72% | +3.08 pp |
| Q1 2012 | 2012-03-31 | −7.21% | +3.51 pp |
| Q4 2011 | 2011-12-31 | −11.63% | −7.29 pp |
| Q3 2011 | 2011-09-30 | −10.01% | −4.11 pp |
| Q2 2011 | 2011-06-30 | −9.80% | −1.28 pp |
| Q1 2011 | 2011-03-31 | −10.72% | — |
| Q4 2010 | 2010-12-31 | −4.35% | — |
| Q3 2010 | 2010-09-30 | −5.91% | — |
| Q2 2010 | 2010-06-30 | −8.52% | — |
Alnylam Pharmaceuticals return on equity trends
Over the last five fiscal years, Alnylam Pharmaceuticals's return on equity increased from −69.92% to 73.28%, a change of +143.21 percentage points. The latest reported quarter, Q2 2026, shows 13.54%.
About the metric
What return on equity (ROE) means
Return on equity (ROE) measures how much net income a company generates relative to shareholders’ equity. It can help evaluate how efficiently equity capital is used, but unusually high or negative values may reflect leverage, losses, or a small equity base.
Calculation and source
How return on equity is calculated
TickerStat calculates ROE as SEC-reported net income divided by average stockholders’ equity at the beginning and end of the fiscal period. Periods with missing or non-positive average equity are omitted. Quarterly ROE uses quarterly net income and is not annualized. Fiscal periods can differ from calendar years, so exact period-end dates are included.
Review Alnylam Pharmaceuticals source filings ↗