Revenue
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $593.8M | $573.4M | $551.5M | $555.5M | $513.7M | $388.5M | $334.2M | $631.6M | $527.5M | $434.0M | $552.7M | $482.8M | $422.4M | $489.0M | $688.1M | $593.0M | $218.7M |
| Gross profit | $270.3M | $254.6M | $239.2M | $255.6M | $243.8M | $172.1M | $134.6M | $246.1M | $198.9M | $156.7M | $189.1M | $167.3M | $132.3M | $159.5M | $223.0M | $166.3M | −$6.0M |
| Gross margin | 45.52% | 44.40% | 43.38% | 46.01% | 47.46% | 44.31% | 40.28% | 38.96% | 37.70% | 36.10% | 34.21% | 34.66% | 31.32% | 32.61% | 32.41% | 28.04% | −2.74% |
| Research & development | $30.4M | $31.5M | $32.1M | $27.5M | $22.4M | $17.8M | $17.3M | $46.9M | $39.9M | $44.2M | $52.2M | $52.6M | $46.2M | $44.7M | $39.8M | $31.2M | $31.6M |
| Operating expenses | $297.1M | $305.9M | $300.5M | $280.3M | $274.9M | $208.7M | $182.0M | $214.7M | $184.6M | $173.7M | $172.2M | $170.0M | $149.1M | $157.8M | $143.4M | $119.3M | $222.0M |
| Operating income | −$26.8M | −$51.3M | −$61.2M | −$24.7M | −$31.1M | −$36.6M | −$47.4M | $31.4M | $14.3M | −$17.1M | $16.9M | −$2.7M | −$16.8M | $1.6M | $79.6M | $47.0M | −$228.0M |
| Operating margin | −4.52% | −8.94% | −11.11% | −4.45% | −6.05% | −9.42% | −14.19% | 4.97% | 2.71% | −3.93% | 3.06% | −0.56% | −3.98% | 0.34% | 11.57% | 7.93% | −104.26% |
| EBITDA | $34.4M | $39.5M | $24.3M | $29.0M | $34.2M | $28.9M | $7.0M | $68.8M | $42.5M | $11.0M | $42.0M | $20.8M | $7.4M | $23.3M | $96.8M | $65.4M | −$202.2M |
| EBITDA margin | 5.79% | 6.88% | 4.41% | 5.21% | 6.67% | 7.44% | 2.10% | 10.90% | 8.05% | 2.53% | 7.61% | 4.30% | 1.74% | 4.76% | 14.07% | 11.03% | −92.44% |
| Net income | −$55.8M | −$164.9M | −$14.6M | $2.13B | $110.7M | $64.9M | $437.4M | $116.6M | $62.6M | −$69.5M | $14.2M | $31.4M | −$2.2M | $136.8M | $130.4M | $59.8M | −$227.9M |
| Net profit margin | −9.39% | −28.76% | −2.65% | 383.95% | 21.56% | 16.69% | 130.89% | 18.46% | 11.87% | −16.01% | 2.57% | 6.50% | −0.52% | 27.97% | 18.95% | 10.09% | −104.18% |
| Basic EPSper basic share | -$1.22 | -$3.10 | -$0.22 | $28.48 | $1.49 | $0.88 | $6.08 | $1.65 | $0.90 | -$1.01 | $0.21 | $0.47 | -$0.03 | $2.10 | $2.02 | $0.94 | -$3.62 |
| Diluted EPSper diluted share | -$1.22 | -$3.10 | -$0.22 | $28.48 | $1.49 | $0.88 | $6.04 | $1.64 | $0.89 | -$1.01 | $0.21 | $0.46 | -$0.03 | $2.08 | $2.01 | $0.93 | -$3.62 |
Reported shareholders
| Holder | % owned |
|---|---|
BlackRock, Inc. | 17.20%7.53M shares |
Politan Capital Management LP | 10.56%4.62M shares |
Koffey Quentin | ≈10.56%4.62M shares |
VANGUARD PORTFOLIO MANAGEMENT LLC | 5.70%2.49M shares |
VANGUARD CAPITAL MANAGEMENT LLC | 4.27%1.87M shares |
STATE STREET CORP | 4.25%1.86M shares |
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 3.25%1.42M shares |
D. E. Shaw & Co., Inc. | 3.06%1.34M shares |
MORGAN STANLEY | 3.04%1.33M shares |
Front Street Capital Management, Inc. | 2.97%1.3M shares |
DIMENSIONAL FUND ADVISORS LP | 2.82%1.23M shares |
Allspring Global Investments Holdings, LLC | 2.72%1.19M shares |
NEUBERGER BERMAN GROUP LLC | 2.59%1.13M shares |
GEODE CAPITAL MANAGEMENT, LLC | 2.52%1.1M shares |
AMERICAN CAPITAL MANAGEMENT INC | 2.43%1.06M shares |
GW&K Investment Management, LLC | 2.26%988.43K shares |
ROYCE & ASSOCIATES LP | 2.04%891.42K shares |
SNYDER CAPITAL MANAGEMENT L P | 1.99%872.54K shares |
VICTORY CAPITAL MANAGEMENT INC | 1.95%854.01K shares |
AMERIPRISE FINANCIAL INC | 1.75%768.05K shares |
Percentages use 43.76M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| May 18, 2026Form 4 | Cornog William LDirector | BuyCommon · indirect | 10.0K | $16.38 | $163.8K | 19.7K |
| Sep 10, 2025Form 4 | Marotta JohnPresident and CEO | SellCommon | 316 | $29.41 | $9.3K | 106.0K |
| Aug 12, 2025Form 4/A | Pirogova OlgaSVP and CHRO | SellCommon | 1.1K | $28.54 | $31.0K | 18.3K |
| Aug 12, 2025Form 4/A | Zhou GingerSVP and GM, Multiomics | SellCommon | 1.1K | $28.54 | $31.0K | 26.8K |
| Aug 11, 2025Form 4 | Lin Lawrence Y.EVP, CFO and Treasurer | BuyCommon | 2.5K | $27.96 | $69.9K | 46.0K |