C4 Therapeutics annual operating margin
2021
2022
2023
2024
2025
C4 Therapeutics Operating Margin Growth & History (CCCC)
C4 Therapeutics's operating margin was −320.53% for fiscal 2025.
View full C4 Therapeutics company overviewC4 Therapeutics annual operating margin history
| Fiscal year | Period ended | Operating margin | Change (percentage points) |
|---|---|---|---|
| 2025 | 2025-12-31 | −320.53% | +15.61 pp |
| 2024 | 2024-12-31 | −336.15% | +333.69 pp |
| 2023 | 2023-12-31 | −669.84% | −253.27 pp |
| 2022 | 2022-12-31 | −416.56% | −237.17 pp |
| 2021 | 2021-12-31 | −179.39% | — |
C4 Therapeutics quarterly operating margin
Q2.21
Q3.21
Q1.22
Q2.22
Q3.22
Q4.22
Q1.23
Q2.23
Q3.23
Q4.23
Q1.24
Q2.24
Q3.24
Q4.24
Q1.25
Q2.25
Q3.25
Q4.25
Q1.26
Q2.26
| Fiscal quarter | Period ended | Operating margin | Change (percentage points) |
|---|---|---|---|
| Q2 2026 | 2026-06-30 | −397.88% | +43.11 pp |
| Q1 2026 | 2026-03-31 | −451.64% | −48.71 pp |
| Q4 2025 | 2025-12-31 | −210.10% | +518.29 pp |
| Q3 2025 | 2025-09-30 | −306.43% | −122.57 pp |
| Q2 2025 | 2025-06-30 | −440.99% | −262.39 pp |
| Q1 2025 | 2025-03-31 | −402.93% | +657.26 pp |
| Q4 2024 | 2024-12-31 | −728.39% | +419.32 pp |
| Q3 2024 | 2024-09-30 | −183.86% | +67.30 pp |
| Q2 2024 | 2024-06-30 | −178.59% | +1231.62 pp |
| Q1 2024 | 2024-03-31 | −1,060.18% | −96.42 pp |
| Q4 2023 | 2023-12-31 | −1,147.72% | +194.02 pp |
| Q3 2023 | 2023-09-30 | −251.16% | +229.86 pp |
| Q2 2023 | 2023-06-30 | −1,410.21% | −1212.26 pp |
| Q1 2023 | 2023-03-31 | −963.77% | −553.93 pp |
| Q4 2022 | 2022-12-31 | −1,341.73% | −1056.39 pp |
| Q3 2022 | 2022-09-30 | −481.02% | −254.91 pp |
| Q2 2022 | 2022-06-30 | −197.95% | — |
| Q1 2022 | 2022-03-31 | −409.84% | — |
| Q3 2021 | 2021-09-30 | −285.34% | — |
| Q2 2021 | 2021-06-30 | −226.11% | — |
C4 Therapeutics operating margin trends
Across the available reported history, C4 Therapeutics's operating margin increased from −336.15% to −320.53%, a change of +15.61 percentage points. The latest reported quarter, Q2 2026, shows −397.88%.
About the metric
What operating margin means
Operating margin measures the percentage of revenue left after operating costs and expenses. It shows how much operating profit a company generates from each dollar of revenue.
Calculation and source
How operating margin is calculated
TickerStat calculates operating margin as SEC-reported operating income divided by SEC-reported revenue for the same fiscal period. Changes are shown in percentage points. Fiscal periods can differ from calendar years, so exact period-end dates are included.
Review C4 Therapeutics filings at SEC.gov ↗