Cyclerion Therapeutics Net Profit Margin Growth & History (CYCN)
Cyclerion Therapeutics's net profit margin was −170.11% for fiscal 2025.
View full Cyclerion Therapeutics company overviewCyclerion Therapeutics annual net profit margin history
| Fiscal year | Period ended | Net profit margin | Change (percentage points) |
|---|---|---|---|
| 2025 | 2025-12-31 | −170.11% | −17.26 pp |
| 2024 | 2024-12-31 | −152.85% | — |
| 2022 | 2022-12-31 | −14,841.08% | −13530.90 pp |
| 2021 | 2021-12-31 | −1,310.17% | +2078.42 pp |
| 2020 | 2020-12-31 | −3,388.59% | −659.32 pp |
| 2019 | 2019-12-31 | −2,729.27% | — |
Cyclerion Therapeutics quarterly net profit margin
| Fiscal quarter | Period ended | Net profit margin | Change (percentage points) |
|---|---|---|---|
| Q4 2025 | 2025-12-31 | −77.95% | −107.30 pp |
| Q3 2025 | 2025-09-30 | −111.54% | +261.14 pp |
| Q2 2025 | 2025-06-30 | −348.39% | — |
| Q1 2025 | 2025-03-31 | −1,764.20% | — |
| Q4 2024 | 2024-12-31 | 29.35% | — |
| Q3 2024 | 2024-09-30 | −372.68% | — |
| Q2 2022 | 2022-06-30 | −4,375.16% | −3835.76 pp |
| Q1 2022 | 2022-03-31 | −1,825.32% | +9390.81 pp |
| Q4 2021 | 2021-12-31 | −3,237.03% | +11220.11 pp |
| Q3 2021 | 2021-09-30 | −3,244.25% | +1458.75 pp |
| Q2 2021 | 2021-06-30 | −539.40% | +2068.61 pp |
| Q1 2021 | 2021-03-31 | −11,216.13% | −9221.26 pp |
| Q4 2020 | 2020-12-31 | −14,457.14% | — |
| Q3 2020 | 2020-09-30 | −4,703.00% | −2748.99 pp |
| Q2 2020 | 2020-06-30 | −2,608.01% | −626.81 pp |
| Q1 2020 | 2020-03-31 | −1,994.87% | — |
| Q3 2019 | 2019-09-30 | −1,954.01% | — |
| Q2 2019 | 2019-06-30 | −1,981.20% | — |
Cyclerion Therapeutics net profit margin trends
Over the last five fiscal years, Cyclerion Therapeutics's net profit margin increased from −3,388.59% to −170.11%, a change of +3218.48 percentage points. The latest reported quarter, Q4 2025, shows −77.95%.
What net profit margin means
Net profit margin measures the percentage of revenue remaining as net income after operating costs, interest, taxes, and other expenses. It shows how much bottom-line profit or loss a company generates from each dollar of revenue.
How net profit margin is calculated
TickerStat calculates net profit margin as SEC-reported net income divided by SEC-reported revenue for the same fiscal period. Changes are shown in percentage points. Fiscal periods can differ from calendar years, so exact period-end dates are included.
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