Cyclerion Therapeutics annual operating margin
2019
2020
2021
2022
2024
2025
Cyclerion Therapeutics Operating Margin Growth & History (CYCN)
Cyclerion Therapeutics's operating margin was −239.78% for fiscal 2025.
View full Cyclerion Therapeutics company overviewCyclerion Therapeutics annual operating margin history
| Fiscal year | Period ended | Operating margin | Change (percentage points) |
|---|---|---|---|
| 2025 | 2025-12-31 | −239.78% | −58.38 pp |
| 2024 | 2024-12-31 | −181.40% | — |
| 2022 | 2022-12-31 | −6,242.42% | −4842.25 pp |
| 2021 | 2021-12-31 | −1,400.18% | +2139.24 pp |
| 2020 | 2020-12-31 | −3,539.42% | −765.13 pp |
| 2019 | 2019-12-31 | −2,774.28% | — |
Cyclerion Therapeutics quarterly operating margin
Q2.19
Q3.19
Q1.20
Q2.20
Q3.20
Q4.20
Q1.21
Q2.21
Q3.21
Q4.21
Q1.22
Q2.22
Q3.24
Q4.24
Q1.25
Q2.25
Q3.25
Q4.25
| Fiscal quarter | Period ended | Operating margin | Change (percentage points) |
|---|---|---|---|
| Q4 2025 | 2025-12-31 | −81.76% | −109.55 pp |
| Q3 2025 | 2025-09-30 | −114.97% | +466.47 pp |
| Q2 2025 | 2025-06-30 | −1,797.85% | — |
| Q1 2025 | 2025-03-31 | −1,798.77% | — |
| Q4 2024 | 2024-12-31 | 27.80% | — |
| Q3 2024 | 2024-09-30 | −581.44% | — |
| Q2 2022 | 2022-06-30 | −4,389.87% | −3850.67 pp |
| Q1 2022 | 2022-03-31 | −1,826.16% | +19778.68 pp |
| Q4 2021 | 2021-12-31 | −2,695.30% | +11758.83 pp |
| Q3 2021 | 2021-09-30 | −3,242.82% | +2202.18 pp |
| Q2 2021 | 2021-06-30 | −539.20% | +2087.24 pp |
| Q1 2021 | 2021-03-31 | −21,604.84% | −19574.37 pp |
| Q4 2020 | 2020-12-31 | −14,454.14% | — |
| Q3 2020 | 2020-09-30 | −5,445.00% | −3440.99 pp |
| Q2 2020 | 2020-06-30 | −2,626.44% | −596.09 pp |
| Q1 2020 | 2020-03-31 | −2,030.47% | — |
| Q3 2019 | 2019-09-30 | −2,004.01% | — |
| Q2 2019 | 2019-06-30 | −2,030.34% | — |
Cyclerion Therapeutics operating margin trends
Over the last five fiscal years, Cyclerion Therapeutics's operating margin increased from −3,539.42% to −239.78%, a change of +3299.64 percentage points. The latest reported quarter, Q4 2025, shows −81.76%.
About the metric
What operating margin means
Operating margin measures the percentage of revenue left after operating costs and expenses. It shows how much operating profit a company generates from each dollar of revenue.
Calculation and source
How operating margin is calculated
TickerStat calculates operating margin as SEC-reported operating income divided by SEC-reported revenue for the same fiscal period. Changes are shown in percentage points. Fiscal periods can differ from calendar years, so exact period-end dates are included.
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