Denali Therapeutics annual r&d spending
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
Denali Therapeutics R&D Spending Growth & History (DNLI)
Denali Therapeutics's r&d spending was $418.8M for fiscal 2025.
View full Denali Therapeutics company overviewDenali Therapeutics annual r&d spending history
| Fiscal year | Period ended | R&D spending | Change | Growth |
|---|---|---|---|---|
| 2025 | 2025-12-31 | $418.8M | $22.3M | +5.63% |
| 2024 | 2024-12-31 | $396.4M | −$27.4M | −6.47% |
| 2023 | 2023-12-31 | $423.9M | $65.1M | +18.16% |
| 2022 | 2022-12-31 | $358.7M | $93.4M | +35.19% |
| 2021 | 2021-12-31 | $265.4M | $52.7M | +24.80% |
| 2020 | 2020-12-31 | $212.6M | $19.2M | +9.95% |
| 2019 | 2019-12-31 | $193.4M | $50.2M | +35.06% |
| 2018 | 2018-12-31 | $143.2M | $68.7M | +92.30% |
| 2017 | 2017-12-31 | $74.5M | −$1.2M | −1.64% |
| 2016 | 2016-12-31 | $75.7M | — | — |
Denali Therapeutics quarterly r&d spending
Q1.17
Q2.17
Q3.17
Q4.17
Q1.18
Q2.18
Q3.18
Q4.18
Q1.19
Q2.19
Q3.19
Q4.19
Q1.20
Q2.20
Q3.20
Q4.20
Q1.21
Q2.21
Q3.21
Q4.21
Q1.22
Q2.22
Q3.22
Q4.22
Q1.23
Q2.23
Q3.23
Q4.23
Q1.24
Q2.24
Q3.24
Q4.24
Q1.25
Q2.25
Q3.25
Q4.25
Q1.26
Q2.26
| Fiscal quarter | Period ended | R&D spending | Change | YoY change |
|---|---|---|---|---|
| Q2 2026 | 2026-06-30 | $97.0M | −$5.7M | −5.53% |
| Q1 2026 | 2026-03-31 | $103.8M | −$12.4M | −10.65% |
| Q4 2025 | 2025-12-31 | $97.9M | −$1.9M | −1.89% |
| Q3 2025 | 2025-09-30 | $102.0M | $3.7M | +3.78% |
| Q2 2025 | 2025-06-30 | $102.7M | $11.3M | +12.36% |
| Q1 2025 | 2025-03-31 | $116.2M | $9.2M | +8.61% |
| Q4 2024 | 2024-12-31 | $99.8M | −$8.0M | −7.44% |
| Q3 2024 | 2024-09-30 | $98.2M | $8.5M | +9.47% |
| Q2 2024 | 2024-06-30 | $91.4M | −$6.1M | −6.28% |
| Q1 2024 | 2024-03-31 | $107.0M | −$21.8M | −16.92% |
| Q4 2023 | 2023-12-31 | $107.8M | $15.7M | +17.04% |
| Q3 2023 | 2023-09-30 | $89.7M | $2.0M | +2.22% |
| Q2 2023 | 2023-06-30 | $97.5M | $4.8M | +5.16% |
| Q1 2023 | 2023-03-31 | $128.8M | $42.7M | +49.62% |
| Q4 2022 | 2022-12-31 | $92.1M | $24.2M | +35.70% |
| Q3 2022 | 2022-09-30 | $87.8M | $16.2M | +22.68% |
| Q2 2022 | 2022-06-30 | $92.7M | $27.0M | +41.13% |
| Q1 2022 | 2022-03-31 | $86.1M | $25.9M | +43.00% |
| Q4 2021 | 2021-12-31 | $67.9M | $13.1M | +23.99% |
| Q3 2021 | 2021-09-30 | $71.6M | $17.9M | +33.25% |
| Q2 2021 | 2021-06-30 | $65.7M | $12.6M | +23.63% |
| Q1 2021 | 2021-03-31 | $60.2M | $9.2M | +18.02% |
| Q4 2020 | 2020-12-31 | $54.7M | $3.2M | +6.19% |
| Q3 2020 | 2020-09-30 | $53.7M | $1.2M | +2.21% |
| Q2 2020 | 2020-06-30 | $53.2M | $1.3M | +2.44% |
| Q1 2020 | 2020-03-31 | $51.0M | $13.6M | +36.40% |
| Q4 2019 | 2019-12-31 | $51.6M | $11.6M | +29.17% |
| Q3 2019 | 2019-09-30 | $52.5M | $22.2M | +73.29% |
| Q2 2019 | 2019-06-30 | $51.9M | −$250,000 | −0.48% |
| Q1 2019 | 2019-03-31 | $37.4M | $16.6M | +79.66% |
| Q4 2018 | 2018-12-31 | $39.9M | $21.4M | +116.06% |
| Q3 2018 | 2018-09-30 | $30.3M | $11.8M | +63.76% |
| Q2 2018 | 2018-06-30 | $52.1M | $33.1M | +174.33% |
| Q1 2018 | 2018-03-31 | $20.8M | $2.3M | +12.72% |
| Q4 2017 | 2017-12-31 | $18.5M | — | — |
| Q3 2017 | 2017-09-30 | $18.5M | — | — |
| Q2 2017 | 2017-06-30 | $19.0M | — | — |
| Q1 2017 | 2017-03-31 | $18.5M | — | — |
Denali Therapeutics r&d spending trends
Over the last five fiscal years, Denali Therapeutics's r&d spending increased from $212.6M to $418.8M, a change of $206.2M. The latest reported quarter, Q2 2026, shows $97.0M.
About the metric
What research and development spending means
Research and development (R&D) spending covers the costs of creating and improving products, services, software, technologies, and processes. Higher R&D spending may support future innovation, but the amount alone does not show whether those investments will generate returns.
Calculation and source
SEC-reported R&D expense
TickerStat standardizes research and development expense reported in company SEC filings, including the software-specific US-GAAP R&D concept when it is the filer’s primary R&D expense line. It is historical company-reported spending, not an estimate or forecast. Fiscal periods can differ from calendar years, so exact period-end dates are included.
Review Denali Therapeutics source filings ↗