Revenue
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $65.3M | $67.6M | $79.2M | $86.2M | $97.1M | $122.5M | $205.2M | $206.6M | $102.8M | $88.3M | $160.9M | $47.7M | $32.1M | $41.7M | $41.9M |
| Research & development | $106.7M | $131.5M | $163.5M | $164.5M | $174.1M | $136.8M | $142.2M | $94.9M | $57.5M | $40.5M | $23.2M | $18.7M | $16.8M | $15.1M | $11.5M |
| Operating expenses | $150.7M | $189.3M | $216.4M | $210.0M | $206.6M | $164.1M | $168.5M | $118.3M | $78.2M | $57.4M | $36.7M | $28.8M | $23.0M | $20.4M | $16.6M |
| Operating income | −$85.3M | −$121.7M | −$137.2M | −$123.8M | −$109.6M | −$41.6M | $36.7M | $88.3M | $24.6M | $30.8M | $124.1M | $19.0M | $9.0M | $21.3M | $25.3M |
| Operating margin | −130.65% | −179.92% | −173.23% | −143.74% | −112.88% | −34.00% | 17.90% | 42.75% | 23.94% | 34.94% | 77.17% | 39.77% | 28.17% | 51.05% | 60.41% |
| EBITDA | −$80.8M | −$119.4M | −$134.8M | −$120.9M | −$106.2M | −$38.0M | $40.0M | $90.8M | $26.8M | $32.5M | $124.8M | $19.3M | $9.3M | $21.5M | $25.8M |
| EBITDA margin | −123.63% | −176.47% | −170.24% | −140.29% | −109.44% | −31.02% | 19.49% | 43.97% | 26.02% | 36.82% | 77.57% | 40.50% | 28.86% | 51.46% | 61.60% |
| Net income | −$81.9M | −$116.0M | −$133.8M | −$121.8M | −$79.0M | −$36.2M | $46.4M | $72.0M | $17.7M | $21.7M | $79.0M | $34.4M | $9.6M | $21.4M | $23.3M |
| Net profit margin | −125.36% | −171.58% | −168.95% | −141.31% | −81.38% | −29.53% | 22.60% | 34.82% | 17.23% | 24.55% | 49.10% | 72.14% | 30.03% | 51.31% | 55.66% |
| Basic EPSper basic share | -$3.84 | -$5.48 | -$6.38 | -$5.91 | -$3.92 | -$1.81 | $2.37 | $3.74 | $0.93 | $1.14 | $4.23 | $1.88 | -$0.67 | $1.26 | $1.40 |
| Diluted EPSper diluted share | -$3.84 | -$5.48 | -$6.38 | -$5.91 | -$3.92 | -$1.81 | $2.21 | $3.48 | $0.91 | $1.13 | $4.09 | $1.80 | -$0.67 | $1.13 | $1.32 |
Reported shareholders
| Holder | % owned |
|---|---|
Jupiter Topco LLC | 12.55%3.65M shares |
BlackRock, Inc. | 11.14%3.24M shares |
Krensavage Asset Management, LLC | 9.84%2.87M shares |
FARALLON CAPITAL MANAGEMENT, L.L.C. | 8.30%2.42M shares |
Deep Track Capital, LP | 4.96%1.44M shares |
ADAR1 Capital Management, LLC | 4.62%1.34M shares |
VANGUARD CAPITAL MANAGEMENT LLC | 4.16%1.21M shares |
Spruce Street Capital LP | 3.74%1.09M shares |
ACADIAN ASSET MANAGEMENT LLC | 3.70%1.08M shares |
VANGUARD PORTFOLIO MANAGEMENT LLC | 3.47%1.01M shares |
Luly Jay R. | ≈2.99%871.87K shares |
GEODE CAPITAL MANAGEMENT, LLC | 2.67%776.63K shares |
MILLENNIUM MANAGEMENT LLC | 2.21%643.97K shares |
STATE STREET CORP | 1.98%576.12K shares |
RENAISSANCE TECHNOLOGIES LLC | 1.91%557.6K shares |
Hillsdale Investment Management Inc. | 1.61%468K shares |
GOLDMAN SACHS GROUP INC | 1.60%464.65K shares |
Or Yat Sun | ≈1.29%374.85K shares |
MORGAN STANLEY | 1.08%315.73K shares |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.03%301.15K shares |
Percentages use 29.12M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Dec 5, 2025Form 4 | Capps Kathleen S.See Remarks | SellCommon Stock | 323 | $14.23 | $4.6K | 8.4K |
| Dec 5, 2025Form 4 | Trout Harry R. IIISee Remarks | SellCommon Stock | 542 | $14.23 | $7.7K | 16.3K |
| Dec 5, 2025Form 4 | Rottinghaus Scott T.Chief Medical Officer | SellCommon Stock | 798 | $14.23 | $11.4K | 21.8K |
| Dec 5, 2025Form 4 | Luu BrendanChief Business Officer | SellCommon Stock | 1.4K | $14.23 | $19.8K | 38.3K |
| Dec 5, 2025Form 4 | Kieffer Tara LynnChief Product Strategy Officer | SellCommon Stock | 2.1K | $14.23 | $30.0K | 30.6K |