Revenue
2018
2019
2020
2021
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $4.27B | $4.07B | $3.83B | $3.66B | $3.09B | $2.36B | $2.16B | $1.89B | $1.62B | $1.49B | $1.32B | $1.17B | $872.4M | $586.0M | $272.3M | $173.8M | $128.4M |
| Research & development | $782.7M | $884.0M | $849.7M | $590.5M | $505.7M | $335.4M | $299.7M | $226.6M | $198.4M | $162.3M | $135.3M | $85.2M | $41.6M | $20.5M | $14.1M | $25.6M | $36.6M |
| Operating expenses | — | — | — | — | — | — | — | $1.28B | $1.09B | $896.3M | $816.6M | $977.3M | $532.1M | $388.1M | $144.4M | $116.0M | $112.5M |
| Operating income | −$430.2M | $716.6M | $578.6M | −$65.5M | $170.3M | $378.1M | $532.4M | $614.8M | $528.8M | $591.7M | $508.2M | $195.6M | $340.3M | $197.8M | $127.8M | $57.8M | $15.9M |
| EBITDAderived | −$388.6M | $749.4M | $609.0M | −$35.2M | $197.0M | $396.8M | $547.7M | $630.0M | $541.9M | $603.5M | $518.1M | $329.3M | $422.4M | $272.1M | $135.7M | $66.5M | $25.0M |
| Net income | −$356.1M | $560.1M | $414.8M | −$224.1M | −$329.7M | $238.6M | $523.4M | $447.1M | $487.8M | $396.8M | $329.5M | $58.4M | $216.3M | $288.6M | $125.0M | $32.8M | −$6.8M |
| Basic EPSper diluted share | -$5.84 | $9.06 | $6.55 | -$3.58 | -$5.52 | $4.28 | $9.22 | $7.45 | $8.13 | $6.56 | $5.38 | $0.98 | $3.71 | $5.09 | $3.01 | $0.90 | -$0.23 |
| Diluted EPSper diluted share | -$5.84 | $8.65 | $6.10 | -$3.58 | -$5.52 | $4.22 | $9.09 | $7.30 | $7.96 | $6.41 | $5.23 | $0.93 | $3.51 | $4.79 | $2.67 | $0.83 | -$0.23 |
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Jun 15, 2026Form 4 · 10b5-1 | Smith Mark DouglasDirector | SellOrdinary Shares | 1.2K | $230.55 | $266.7K | 9.7K |
| Jun 10, 2026Form 4 · 10b5-1 | Patil Neena MEVP & Chief Legal Officer | SellOrdinary Shares | 1.2K | $231.83 | $278.2K | 51.5K |
| Jun 1, 2026Form 4 · 10b5-1 | COZADD BRUCE CDirector | SellOrdinary Shares | 6.0K | $235.12 | $1.41M | 372.7K |
| May 28, 2026Form 4 | Pearce SamanthaEVP, Chief Commercial Officer | SellOrdinary Shares | 6.9K | $235.41 | $1.63M | 50.3K |
| May 28, 2026Form 4 · 10b5-1 | Patil Neena MEVP & Chief Legal Officer | SellOrdinary Shares | 1.2K | $236.97 | $282.5K | 52.6K |