Revenue
2012
2013
2014
2015
2016
2017
2018
2019
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | — | — | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Research & development | $154.2M | $73.3M | $27.7M | $24.3M | $38.4M | $31.4M | $20.8M | $47.9M | $40.8M | $39.9M | $54.6M | $27.4M | $9.6M | $11.5M |
| Operating expenses | $172.5M | $90.9M | $41.8M | $36.5M | $50.5M | $42.8M | $23.2M | $61.1M | $53.0M | $58.2M | $73.8M | $35.5M | $13.8M | $13.8M |
| Operating income | −$172.5M | −$90.9M | −$41.8M | −$36.5M | −$50.5M | −$42.8M | −$23.2M | −$61.1M | −$53.0M | −$58.2M | −$73.8M | −$35.5M | −$13.8M | −$13.8M |
| EBITDA | −$172.1M | −$90.6M | −$41.4M | −$36.2M | −$50.1M | −$42.6M | −$23.1M | −$60.9M | −$52.8M | −$58.0M | −$73.7M | −$35.5M | −$13.8M | −$13.8M |
| Net income | −$165.7M | −$80.6M | −$36.9M | −$35.4M | −$50.6M | −$42.5M | −$23.1M | −$61.4M | −$52.0M | −$57.9M | −$74.3M | −$36.5M | −$14.0M | −$13.9M |
| Basic EPSper basic share | -$2.27 | -$1.32 | -$0.84 | -$1.37 | -$2.95 | -$3.57 | -$3.80 | -$1.90 | -$1.90 | -$2.12 | -$2.78 | -$3.00 | -$19.53 | -$19.65 |
| Diluted EPSper diluted share | -$2.27 | -$1.32 | -$0.84 | -$1.37 | -$2.95 | -$3.57 | -$3.80 | -$1.90 | -$1.90 | -$2.12 | -$2.78 | -$3.00 | -$19.53 | -$19.65 |
Reported shareholders
| Holder | % owned |
|---|---|
DEERFIELD MANAGEMENT COMPANY, L.P. | 34.28%35.61M shares |
Blue Owl Capital Holdings LP | 8.82%9.16M shares |
BlackRock, Inc. | 5.47%5.68M shares |
Defilade Capital Management, L.P. | 3.53%3.67M shares |
Driehaus Capital Management LLC | 3.05%3.16M shares |
VANGUARD CAPITAL MANAGEMENT LLC | 2.86%2.97M shares |
RTW INVESTMENTS, LP | 2.47%2.57M shares |
AQR CAPITAL MANAGEMENT LLC | 2.28%2.37M shares |
MARSHALL WACE, LLP | 1.94%2.01M shares |
DAFNA Capital Management LLC | 1.93%2.01M shares |
GOLDMAN SACHS GROUP INC | 1.69%1.75M shares |
GEODE CAPITAL MANAGEMENT, LLC | 1.62%1.68M shares |
Qube Research & Technologies Ltd | 1.58%1.64M shares |
CITADEL ADVISORS LLC | 1.40%1.46M shares |
STATE STREET CORP | 1.36%1.41M shares |
VANGUARD PORTFOLIO MANAGEMENT LLC | 1.35%1.4M shares |
Woodline Partners LP | 1.35%1.4M shares |
MILLENNIUM MANAGEMENT LLC | 1.28%1.33M shares |
DIMENSIONAL FUND ADVISORS LP | 0.93%961.08K shares |
FMR LLC | 0.90%937.37K shares |
Percentages use 103.88M shares of this listed class outstanding on Jun 30, 2026.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Feb 27, 2026Form 4 | Deerfield Mgmt HIF, L.P. +9Director,TenPercentOwner,Other | BuyCommon Stock · indirect | 2.00M | $5.00 | $10.00M | 6.21M |
| Feb 27, 2026Form 4 | Deerfield Mgmt HIF, L.P. +9Director,TenPercentOwner,Other | BuyCommon Stock · indirect | 832.0K | $5.00 | $4.16M | 8.15M |
| Feb 27, 2026Form 4 | Deerfield Mgmt HIF, L.P. +9Director,TenPercentOwner,Other | BuyCommon Stock · indirect | 1.08M | $5.00 | $5.42M | 10.62M |
| Feb 27, 2026Form 4 | Deerfield Mgmt HIF, L.P. +9Director,TenPercentOwner,Other | BuyCommon Stock · indirect | 1.08M | $5.00 | $5.42M | 10.62M |
| Feb 27, 2026Form 4 | Hamilton Thomas EdwardDirector | BuyCommon Stock | 100.0K | $5.00 | $500.0K | 664.8K |