Lyell Immunopharma, Inc. (LYEL)

Price$14.37Cached quote
LYELNasdaq
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Financial charts

Revenue

Total cash / debt

CashTotal debt

Financial statements

7 annual periodsNewest to oldest
2025202420232022202120202019
Revenue$36,000$61,000$130,000$84.7M$10.7M$7.8M$657,000
Research & development$158.7M$171.6M$182.9M$159.2M$138.7M$182.2M$63.6M
Operating expenses$269.4M$358.8M$247.1M$271.7M$225.4M$219.7M$102.7M
Operating income−$269.4M−$358.8M−$247.0M−$187.1M−$214.8M−$211.9M−$102.1M
Operating margin−748,344.44%−588,122.95%−190,006.15%−220.89%−2,016.68%−2,732.56%−15,538.66%
EBITDA−$257.9M−$339.1M−$226.8M−$169.0M−$201.2M−$207.6M−$100.8M
EBITDA margin−716,291.67%−555,940.98%−174,429.23%−199.61%−1,888.75%−2,677.19%−15,347.49%
Net income−$274.4M−$343.0M−$234.6M−$183.1M−$250.2M−$204.5M−$129.4M
Net profit margin−762,355.56%−562,285.25%−180,486.15%−216.24%−2,349.47%−2,636.31%−19,692.09%
Basic EPSper basic share-$16.06-$26.23-$18.70-$14.80-$36.80-$313.80-$480.80
Diluted EPSper diluted share-$16.06-$26.23-$18.70-$14.80-$36.80-$313.80-$480.80

Owners

Reported shareholders

Reference date Jun 30, 2026
BERNS PAUL L / Burow Kristina / ARCH Venture Partners XIII, LLC / ARCH Venture Partners XIII, L.P. / BYBEE CLINTON / GILLIS STEVEN / NELSEN ROBERT / ARCH Venture Fund XIII, L.P. / CRANDELL KEITH · ≈13.88% of listed sharesARCH Venture Management, LLC · 13.88% of listed sharesARCH Venture Partners IX Overage, L.P. / ARCH Venture Partners IX, L.P. / ARCH Venture Partners IX, LLC / ARCH Venture Fund IX, L.P. / ARCH Venture Fund IX Overage, L.P. · ≈13.88% of listed sharesInnovative Cellular Therapeutics Holdings Ltd · ≈12.54% of listed sharesGSK plc · 6.47% of listed sharesVANGUARD CAPITAL MANAGEMENT LLC · 3.36% of listed sharesOrland Properties Ltd · 3.23% of listed sharesBlackRock, Inc. · 3.10% of listed sharesAlmitas Capital LLC · 2.48% of listed sharesForesite Capital Management V, LLC · 2.04% of listed sharesMILLENNIUM MANAGEMENT LLC · 1.57% of listed sharesOpaleye Management Inc. · 1.47% of listed sharesvenBio Partners LLC · 1.44% of listed sharesGEODE CAPITAL MANAGEMENT, LLC · 1.33% of listed sharesAlphabet Inc. · 1.25% of listed sharesSTATE STREET CORP · 0.79% of listed sharesLang Matthew · ≈0.69% of listed sharesHSG Holding Ltd · 0.65% of listed sharesRENAISSANCE TECHNOLOGIES LLC · 0.56% of listed shares
≈13.88%of listed shares
BERNS PAUL L / Burow Kristina / ARCH Venture Partners XIII, LLC / ARCH Venture Partners XIII, L.P. / BYBEE CLINTON / GILLIS STEVEN / NELSEN ROBERT / ARCH Venture Fund XIII, L.P. / CRANDELL KEITH3.25M shares · Mar 6, 2026
View holders
Top 20 reported holders of LYEL
Holder% owned
BERNS PAUL L / Burow Kristina / ARCH Venture Partners XIII, LLC / ARCH Venture Partners XIII, L.P. / BYBEE CLINTON / GILLIS STEVEN / NELSEN ROBERT / ARCH Venture Fund XIII, L.P. / CRANDELL KEITH
≈13.88%3.25M shares
ARCH Venture Management, LLC
13.88%3.25M shares
ARCH Venture Partners IX Overage, L.P. / ARCH Venture Partners IX, L.P. / ARCH Venture Partners IX, LLC / ARCH Venture Fund IX, L.P. / ARCH Venture Fund IX Overage, L.P.
≈13.88%3.25M shares
Innovative Cellular Therapeutics Holdings Ltd
≈12.54%2.93M shares
GSK plc
6.47%1.51M shares
VANGUARD CAPITAL MANAGEMENT LLC
3.36%786.77K shares
Orland Properties Ltd
3.23%754.7K shares
BlackRock, Inc.
3.10%724.34K shares
Almitas Capital LLC
2.48%581.41K shares
Foresite Capital Management V, LLC
2.04%476.39K shares
MILLENNIUM MANAGEMENT LLC
1.57%367.47K shares
Opaleye Management Inc.
1.47%344.03K shares
venBio Partners LLC
1.44%337.7K shares
GEODE CAPITAL MANAGEMENT, LLC
1.33%310.64K shares
Alphabet Inc.
1.25%293.26K shares
Klausner Richard
—190.56K shares
STATE STREET CORP
0.79%185.32K shares
Lang Matthew
≈0.69%162.5K shares
HSG Holding Ltd
0.65%152.3K shares
RENAISSANCE TECHNOLOGIES LLC
0.56%130.19K shares

Percentages use 23.4M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.

Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.

Source: SEC Form 4 ↗Updated Sep 29, 2026 · Quarterly data

Insider buys & sells

Jul 1, 2024–Jun 30, 2026
Buys7$25.45M disclosed value
Sells (SEC code S)30$526.8K disclosed value
37 recent transactions
TransactionInsiderTypeSharesPriceValueOwned after
Jun 10, 2026Form 4Shook DavidChief Medical OfficerSellCommon Stock2.0K$12.64$25.0K20.9K
May 11, 2026Form 4Bulis Veronica SanchezVP, Corporate ControllerSellCommon Stock217$18.91$4.1K15.4K
May 11, 2026Form 4Lee Gary K.Chief Scientific OfficerSellCommon Stock130$18.92$2.5K17.8K
May 11, 2026Form 4Hill Stephen J.Chief Operating OfficerSellCommon Stock89$18.92$1.7K17.9K
May 11, 2026Form 4Seely LynnPresident and CEOSellCommon Stock388$18.91$7.3K73.9K

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