Revenue
2009
2010
2011
2012
2013
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 · Dec 31 | 2013 · Jun 30 | 2012 | 2011 | 2010 | 2009 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $9.0M | $7.0M | $6.2M | $5.2M | $4.5M | $2.5M | $3.7M | $3.6M | $2.8M | $1.9M | $2.3M | $2.8M | $3.1M | $4.9M | $5.3M | $6.0M | $4.9M | $3.4M |
| Gross profit | $2.6M | $1.5M | $1.8M | $1.1M | $754,000 | $83,000 | $756,000 | $995,000 | $585,000 | $102,000 | −$296,000 | $784,000 | $1.7M | $2.6M | $2.5M | $3.0M | $2.3M | $1.1M |
| Gross margin | 29.50% | 21.49% | 29.12% | 21.60% | 16.77% | 3.34% | 20.32% | 27.63% | 21.19% | 5.39% | −12.81% | 27.82% | 53.56% | 53.15% | 46.74% | 49.85% | 45.52% | 32.83% |
| Research & development | $15.0M | $13.6M | $8.0M | $7.8M | $5.2M | $2.2M | $3.0M | $1.5M | $1.3M | $1.3M | $3.6M | $8.7M | $3.3M | $4.2M | $4.0M | $2.5M | $1.3M | $1.3M |
| Operating expenses | $52.3M | $35.0M | $22.9M | $19.8M | $15.5M | $10.5M | $10.6M | $8.6M | $8.8M | $7.8M | $14.2M | $24.5M | $10.5M | $17.7M | $20.0M | $16.7M | $5.5M | $3.8M |
| Operating income | −$49.6M | −$33.5M | −$21.1M | −$18.7M | −$14.7M | −$10.4M | −$9.8M | −$7.6M | −$8.2M | −$7.6M | −$14.5M | −$23.7M | −$8.8M | −$15.1M | −$17.5M | −$13.7M | −$3.2M | −$2.7M |
| Operating margin | −552.56% | −478.00% | −340.74% | −361.88% | −327.39% | −417.71% | −263.80% | −211.36% | −298.15% | −403.80% | −627.06% | −840.95% | −284.28% | −309.32% | −328.01% | −228.66% | −65.04% | −79.65% |
| EBITDA | $426.4M | $246.5M | $210.9M | $169.3M | −$14.6M | −$10.2M | −$9.7M | −$7.5M | −$8.1M | −$7.5M | −$14.3M | −$23.4M | −$8.7M | −$14.9M | −$17.4M | −$13.6M | −$3.1M | −$2.6M |
| EBITDA margin | 4,748.70% | 3,516.86% | 3,398.18% | 3,273.78% | −323.80% | −411.63% | −259.55% | −207.50% | −292.61% | −396.30% | −620.48% | −831.62% | −280.74% | −305.05% | −325.76% | −227.18% | −63.20% | −77.04% |
| Net income | −$48.8M | −$32.0M | −$19.9M | −$18.5M | −$14.9M | −$10.5M | −$10.0M | −$7.2M | −$8.4M | −$8.5M | −$15.6M | −$25.1M | −$9.3M | −$29.3M | −$17.6M | −$14.7M | −$3.4M | −$2.7M |
| Net profit margin | −543.33% | −456.63% | −320.97% | −357.59% | −331.88% | −424.31% | −269.82% | −201.06% | −305.61% | −446.73% | −674.68% | −890.53% | −300.68% | −600.41% | −328.98% | −244.25% | −69.10% | −79.86% |
| Basic EPSper basic share | -$0.76 | -$0.76 | -$0.82 | -$2.35 | -$2.03 | -$6.97 | -$72.00 | -$250.05 | -$524.70 | -$3,115.80 | -$837.75 | -$2,658.75 | -$1,012.50 | -$5,212.50 | -$3,900.00 | -$3,600.00 | -$1,050.00 | -$900.00 |
| Diluted EPSper diluted share | -$0.76 | -$0.76 | -$0.82 | -$2.35 | -$2.03 | -$6.97 | -$72.00 | -$250.05 | -$524.70 | -$3,115.80 | -$837.75 | -$2,658.75 | -$1,012.50 | -$5,212.50 | -$3,900.00 | -$3,600.00 | -$1,050.00 | -$900.00 |
Reported shareholders
| Holder | % owned |
|---|---|
Nantahala Capital Management, LLC | 14.39%6.75M shares |
Rosalind Advisors, Inc. | 8.32%3.91M shares |
Aberdeen Group plc | 7.88%3.7M shares |
Slosman Marvin | ≈7.58%3.56M shares |
ORBIMED ADVISORS LLC | 6.68%3.13M shares |
Parkman Healthcare Partners LLC | 5.15%2.42M shares |
MARSHALL WACE, LLP | 3.96%1.86M shares |
Shore Craig | ≈2.37%1.11M shares |
Stuka Paul | ≈2.33%1.09M shares |
Gleason Shane Thomas | ≈2.25%1.05M shares |
Soleus Capital Management, L.P. | 2.23%1.05M shares |
Tommasoli Andrea | ≈2.03%954.39K shares |
ROUBIN GARY S | ≈1.78%834.48K shares |
Lawless Michael A | ≈1.47%691.7K shares |
BERMAN MICHAEL | ≈1.27%597.58K shares |
Kester Thomas J | ≈0.98%458.57K shares |
PURA VIDA INVESTMENTS, LLC | 0.96%450.52K shares |
INGALLS & SNYDER LLC | 0.79%368.8K shares |
Verta Patrick | ≈0.66%311.53K shares |
Arnold Kathryn | ≈0.65%303.09K shares |
Percentages use 46.92M shares of this listed class outstanding on Jun 30, 2026. ≈ compares the latest reported holding with a share total from a different date; it is not a confirmed current stake.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| May 27, 2026Form 4 | Stuka PaulDirector | BuyCommon Stock | 20.0K | $0.88 | $17.6K | 667.9K |
| May 19, 2026Form 4 | Gleason Shane ThomasChief Commercial Officer | SellCommon Stock | 22.8K | $1.01 | $23.0K | 1.05M |
| May 14, 2026Form 4 | Stuka PaulDirector | BuyCommon Stock | 5.0K | $1.15 | $5.8K | 647.9K |
| May 13, 2026Form 4 | Stuka PaulDirector | BuyCommon Stock | 10.0K | $1.16 | $11.6K | 642.9K |
| May 12, 2026Form 4 | Slosman MarvinCEO and President | BuyCommon Stock | 21.0K | $1.20 | $25.2K | 3.56M |