Revenue
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $250,000 | $0 | — | $13,520 | $15,394 | $260,000 | $260,000 | $16,246 | $10,417 | $18,833 | $110,000 | $407,708 | $390,625 | $733,438 | — |
| Research & development | $10.2M | $9.1M | $6.9M | $6.5M | $2.4M | $3.1M | $4.1M | $4.0M | $8.1M | $13.2M | $12.6M | $8.4M | $7.3M | $6.1M | $7.4M | $9.2M | $5.3M |
| Operating expenses | $18.1M | $14.9M | $13.3M | $15.7M | $41.9M | $9.3M | $8.6M | $8.5M | $13.6M | $20.7M | $19.2M | $17.5M | $12.6M | $10.6M | $13.4M | $15.9M | $10.5M |
| Operating income | −$18.1M | −$14.9M | −$13.1M | −$15.7M | −$41.9M | −$9.3M | −$8.6M | −$8.3M | −$13.3M | −$20.6M | −$19.2M | −$17.4M | −$12.5M | −$10.2M | −$13.0M | −$15.2M | −$10.5M |
| Operating margin | — | — | −5,228.00% | — | — | −68,764.79% | −56,071.81% | −3,176.71% | −5,118.12% | −127,027.23% | −183,896.78% | −92,581.37% | −11,385.40% | −2,491.11% | −3,325.56% | −2,070.37% | — |
| EBITDA | −$18.1M | −$14.9M | −$13.1M | −$15.7M | −$41.9M | −$9.3M | −$8.5M | −$8.1M | −$13.0M | −$20.3M | −$18.8M | −$17.1M | −$12.3M | −$9.9M | −$12.8M | −$15.1M | −$10.4M |
| EBITDA margin | — | — | −5,226.40% | — | — | −68,742.60% | −55,137.29% | −3,105.25% | −5,006.88% | −124,949.74% | −180,580.47% | −90,730.20% | −11,162.92% | −2,439.32% | −3,277.68% | −2,052.54% | — |
| Net income | −$16.8M | −$14.4M | −$12.3M | −$14.3M | −$26.6M | −$10.3M | −$8.4M | −$4.9M | −$15.7M | −$21.1M | −$20.9M | −$22.6M | −$19.8M | −$10.1M | −$12.5M | −$18.4M | −$10.4M |
| Net profit margin | — | — | −4,920.00% | — | — | −76,346.15% | −54,252.64% | −1,894.08% | −6,025.38% | −129,721.85% | −200,671.03% | −120,154.75% | −18,028.97% | −2,482.54% | −3,204.74% | −2,507.00% | — |
| Basic EPSper basic share | -$0.30 | -$10.19 | -$27.01 | -$247.95 | -$2,144.25 | -$2,790.00 | -$17,100.00 | -$33,930.00 | -$108,000.00 | -$227,700.00 | -$269,100.00 | -$304,200.00 | -$315,900.00 | -$198,900.00 | -$304,200.00 | -$491,400.00 | -$351,000.00 |
| Diluted EPSper diluted share | -$0.30 | -$10.19 | -$27.01 | -$247.95 | -$2,546.10 | -$2,790.00 | -$17,100.00 | -$33,930.00 | -$108,000.00 | -$227,700.00 | -$269,100.00 | -$304,200.00 | -$315,900.00 | -$198,900.00 | -$304,200.00 | -$491,400.00 | -$351,000.00 |
Reported shareholders
| Holder | % owned |
|---|---|
Soleus Capital Management, L.P. | 7.53%13.06M shares |
B Group, Inc. | 6.58%11.41M shares |
AMERIPRISE FINANCIAL INC | 6.38%11.08M shares |
Jupiter Topco LLC | 6.16%10.69M shares |
BlackRock, Inc. | 6.01%10.44M shares |
Octagon Capital Advisors LP | 5.92%10.28M shares |
PERCEPTIVE ADVISORS LLC | 4.85%8.43M shares |
RA CAPITAL MANAGEMENT, L.P. | 4.10%7.12M shares |
FRANKLIN RESOURCES INC | 3.33%5.79M shares |
Point72 Asset Management, L.P. | 3.03%5.25M shares |
Boxer Capital Management, LLC | 2.76%4.8M shares |
ADAGE CAPITAL PARTNERS GP, L.L.C. | 2.59%4.5M shares |
Eversept Partners, LP | 2.41%4.18M shares |
GEODE CAPITAL MANAGEMENT, LLC | 2.17%3.76M shares |
WELLINGTON MANAGEMENT GROUP LLP | 2.13%3.7M shares |
GOLDMAN SACHS GROUP INC | 2.06%3.58M shares |
FEDERATED HERMES, INC. | 1.81%3.14M shares |
Squadron Capital Management LLC | 1.73%3M shares |
Propel Bio Management, LLC | 1.49%2.58M shares |
Vestal Point Capital, LP | 1.44%2.5M shares |
Percentages use 173.6M shares of this listed class outstanding on Jun 30, 2026.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Feb 12, 2026Form 4 | Jones Mitchell LawrenceChief Medical Officer | SellCommon Stock | 2.0K | $1.75 | $3.5K | 13.3K |
| Feb 12, 2026Form 4 | Finley John DavidCEO, CFO | SellCommon Stock | 3.9K | $1.75 | $6.8K | 27.4K |
| Jan 16, 2026Form 4 | Williams Donald AllenDirector | BuyCommon Stock | 5.0K | $1.67 | $8.3K | 10.7K |
| Jan 9, 2026Form 4 | Williams Donald AllenDirector | BuyCommon Stock | 5.0K | $1.88 | $9.4K | 5.7K |